Protein Alignment Ir60a and grin2da

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_009292354.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1916
• Species: Danio rerio
• Alignment Length: 640
• Identity: 109/640 - (17%)
• Similarity: 217/640 - (33%)
• Gaps: 154/640 - (24%)

  Fly    89 PADQIQEGFSKLINEAVTNPGPPDREELFQMRVASDYNITNGTEDKGELILADNYVIVVDSVDRL 153
            |..:|.:|.|.|.:.|              |.:..:|....||...|..::..|....|
Zfish   336 PRRRIAKGVSVLTHGA--------------MALRREYGGARGTSFAGNCMMDGNQTQRV------ 380

  Fly   154 KELMKKKIVEMRSWNPG-ARFLVLFHNATCRNRPL-----GVASNIFKDLMEM----------FY 202
                           || .||   |.|.|...|..     |..:|...|::..          ::
Zfish   381 ---------------PGRIRF---FSNITLSGRDYSFNNDGYLANPLLDVISYTAGRGWEEVGWW 427

  Fly   203 VHRVALLYANSTMNYNLLVNDYYSNVNCRILNVQ------------SVGQC-HDG---KLYPNNA 251
            .:.|..|.......|...:.....:.:.|::.::            ..|.| .|.   :|..||:
Zfish   428 ENGVLRLRYPPWSRYGPFLKPLDDSQHLRVVTLEERPFVIVEPADPGTGSCIRDSVPCRLPLNNS 492

  Fly   252 VVKASMQDYVSGFSPRNCTFFACSSISAPFVEADCILGLE--MRILGFMKNRLKFDVNQTCSLES 314
            :|...:|      |.::|    |...        ||..|:  .:|:||     .:|:....:...
Zfish   493 MVVEGIQ------SMKHC----CKGF--------CIDVLKRLAKIVGF-----TYDLYLVTNGRH 534

  Fly   315 RGEMDGPANWTGLLGKVQNNECDFVFGGYYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQA 379
            ...:||  .|.|::|:|.:...|...|....:.|.::....|..:::...:..:..::...:..|
Zfish   535 GKNIDG--QWNGMVGEVVSKRADMAIGSLTINEERSEVVEFSVPFVETGISVMVSRSNGTVSPSA 597

  Fly   380 LVGIFEAYTWI-GFILILIISWLFWFTLVMILP--------------EPKYYQQLSLTAINALAV 429
            .:..:....|: .|::.|.:..:..|......|              ..|:....|:..:.||..
Zfish   598 FLEPYSPAVWVMMFVMCLSVVAVTVFIFEFFSPVGYNRSLQSGKTAGGSKFTIGKSIWLLWALVF 662

  Fly   430 TISIAVQERPICETTRLFFMALTLYGLNVVATYTSKM------------IATFQDPGYLHQLDEL 482
            ..|:.| |.|...|:::..:....:.:..:|:||:.:            ::...|..:.|..::.
Zfish   663 NNSVPV-ENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYIDTVSGLSDKKFQHPTEQY 726

  Fly   483 TEVVAAGIPFGGHEES-RDWFENDDDMWIFNGYNISPEFIPQSK--NLEAVKWGQRCILSNRMYT 544
            ..:....:|.|..||: |..:.|.....:.|......:.|...|  .|:|..:....:  |.| .
Zfish   727 PPLRFGTVPNGSTEENIRSNYPNMHQYMVRNNQRGVEDAIENLKTGKLDAFIYDAAVL--NYM-A 788

  Fly   545 MQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMRDVGIFQKIDAD--------FRY 601
            .:.....|:......||::       .|:......||..:...|:.:.|.:..|        :..
Zfish   789 RKDEGCKVMTIGSGKVFAT-------TGYGVALHKNSRWKRPLDLALLQLVGDDEIDMLERLWLS 846

  Fly   602 NNTYLNRINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTFIGELIIHRWR 656
            ...:.::|..|..:       |..:::.|.|::|:|....:.|.|..|.::: |:
Zfish   847 GICHNDKIEVMSSK-------LDIDNMAGVFYMLLVAMGLSLLVFAWEHLVY-WK 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grin2da	XP_009292354.1	PBP1_iGluR_NMDA_NR2	42..441	CDD:107373	26/142 (18%)
		PBP2_iGluR_NMDA_Nr2	452..851	CDD:270436	71/434 (16%)
		HisJ	<507..>590	CDD:223904	17/97 (18%)
		Lig_chan	605..877	CDD:278489	48/289 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591617
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830