Protein Alignment Ir60a and gria4a

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_999971.1
• Gene: gria4a / 407735
• ZFINID: ZDB-GENE-020125-7
• Length: 898
• Species: Danio rerio
• Alignment Length: 892
• Identity: 159/892 - (17%)
• Similarity: 262/892 - (29%)
• Gaps: 356/892 - (39%)

  Fly    46 PDVWKAGVGCLDSFAQI--FFFRNPKERFTRAYNLMLVH---------AFHLSSPADQIQEGFSK 99
            |.:|..|.|...|..||  .|.||..:.:|.....:.:|         .|:|....|.|:...|.
Zfish     8 PLLWGLGEGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNATEAPFNLVPHVDNIETANSF 72

  Fly   100 LINEA-----------------------------------VTNPGPPDREELFQMRVASDYNITN 129
            .:..|                                   ||...|.:.|..|.:::....
Zfish    73 AVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLVTPSFPAEGETQFVLQLRPSI---- 133

  Fly   130 GTEDKGELI-LADNY-----VIVVDSVDR----LKELMKKKIVEMRSWNPGARFLVLFHNATCRN 184
                :|.|: |.|:|     |.:.|: ||    |:.:|:|  .....|...|..:..|::|:.|
Zfish   134 ----RGALLSLLDHYDWSRFVFLYDT-DRGYAVLQAIMEK--AGQNGWQVSAICVENFNDASYR- 190

  Fly   185 RPLGVASNIFKDLMEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNVQSVGQCHDGKLY-- 247
                   .:.:||........|..|.|....|.              :..:.|||:...|..|
Zfish   191 -------RLLEDLDRRQEKKFVIDLEAERLQNI--------------LEQIVSVGKHVKGYHYIV 234

  Fly   248 PNNAVVKASMQDYVSGFSPRNCTFFACSSISAPFV------------------------------ 282
            .|......|::.::.|.:  |.|.|.....|.|.|
Zfish   235 ANLGFKDISLERFMHGGA--NVTGFQLVDFSKPMVIKLMQRWNKLDQREYPGSESPPRYTSSLTY 297

  Fly   283 -------EA------------------DCIL--------GLEM-------RILGFMKNRLKFD-- 305
                   ||                  ||:.        |::|       ||.|...| ::||
Zfish   298 DGVLVMAEAFRNLRRQKIDISRRGNAGDCLANPAAPWNQGIDMERTLKQVRIQGLTGN-IQFDHY 361

  Fly   306 ---VNQTC---SLESRGE-------------------------------------MDGP-----A 322
               ||.|.   .|:|.|.                                     |:||     .
Zfish   362 GRRVNYTMDVFELKSNGPRKIGYWNDLDKLVLVQNELSMGNDSAMENRTVIVTTIMEGPYVMLKK 426

  Fly   323 NWTGLLGKVQNNECDFVFGGYYPD--NEVADHF-------------WGSDTYLQDAHT--WY--- 367
            ||....|..|       |.||..|  :|||.|.             :|:    :|..|  |.
Zfish   427 NWEMYEGNEQ-------FEGYCVDLASEVAKHIGIKYKISIVLDGKYGA----RDPETKIWNGMV 480

  Fly   368 -----------------------------------IKMADRRP--------------AWQALVGI 383
                                               |.:..::|              |::..:.|
Zfish   481 GELVYGKAEIAVAPLAITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 545

  Fly   384 FEAYTWIGFILILI--ISWLFWFTLVMILPE------PKYYQQLSLTAINALAVTISIAVQERPI 440
            ..||..:..:|.|:  .|...|.|..   ||      |...........|:|..::...:|:.
Zfish   546 VFAYIGVSVVLFLVSRFSPYEWHTEE---PEEGSDGPPSDQPPNEFGIFNSLWFSLGAFMQQG-- 605

  Fly   441 CETT------RLFFMALTLYGLNVVATYTS---------KMIATFQDPGYLHQLDELTEVVAAGI 490
            |:.|      |:.......:.|.::::||:         :|::..:.   ...|.:.||:....:
Zfish   606 CDFTPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES---AEDLAKQTEIAYGTL 667

  Fly   491 PFGGHEESRDWFEND-----DDMWIFNGYNISPEFIPQSK-NLEAV------KWGQRCILSNRM- 542
            ..|   .::::|...     :.||   .|..|.|....:| ..|.|      |.....:|.:.|
Zfish   668 DSG---STKEFFRRSKIAVYEKMW---SYMKSAEPTVFTKTTAEGVARVRKSKGKYAFLLESTMN 726

  Fly   543 -YTMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMRDVGIFQKIDADFRYNNTYL 606
             ||.|....|.: ....|:.|....:....|......:|..:..:.:.|:..|:...:.|:.
Zfish   727 EYTEQRKPCDTM-KVGGNLDSKGYGVATPKGSQLGTPVNLAVLKLSEAGVLDKLKNKWWYDK--- 787

  Fly   607 NRINKMRPQ----FPETAIVLTTEHLKGPFFILVVGSCWAALTFIGE 649
               .:..|:    ..:::..|:..::.|.|:|||.|...|.|..:.|
Zfish   788 ---GECGPKDSGSKDKSSQALSLSNVAGVFYILVGGLGLAMLVALVE 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
gria4a	NP_999971.1	PBP1_iGluR_AMPA_GluR4	23..393	CDD:107383	73/405 (18%)
		ANF_receptor	34..375	CDD:279440	65/376 (17%)
		PBP2_iGluR_AMPA_GluR4	408..790	CDD:270445	70/413 (17%)
		Lig_chan	540..821	CDD:278489	55/301 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930