Protein Alignment Ir60a and Nmdar1

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 727
• Identity: 136/727 - (18%)
• Similarity: 248/727 - (34%)
• Gaps: 179/727 - (24%)

  Fly    78 LMLVHAF----HLSSPADQIQEGFSKLINEAVTNPGPPD----------REELFQMRVASDYNIT 128
            |.|.||.    |:......:.....::|:.......|.|          .:.|||  .....|||
  Fly   285 LQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQ--YLKSRNIT 347

  Fly   129 NGT-----EDKGELILADNYVIVVDSVDRLKELMKKKIV------EMRS------------WNPG 170
            ..|     :|.|:.|.|...||      .::|..||.:|      .||:            | ||
  Fly   348 GETGQVAFDDNGDRIYAGYDVI------NIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIW-PG 405

  Fly   171 ARFLVLFHNATCRNRPLGVASNIFKDLMEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNV 235
            .:          |.:|.|:          |...|                         .|:|.:
  Fly   406 KQ----------RRKPEGI----------MIPTH-------------------------LRLLTI 425

  Fly   236 QSVGQCHDGKLYPNNAVVKASMQDYVSGFSPRNCTFFACSSISAPFVEADCILGLEMRILGFMKN 300
            :.         .|...|.:....::......|.|..|..|..:|   ...|..|..:.:|..:..
  Fly   426 EE---------KPFVYVRRMGDDEFRCEPDERPCPLFNNSDATA---NEFCCRGYCIDLLIELSK 478

  Fly   301 RLKFDVNQTCSLESR----------GEMDGPANWTGLLGKVQNNECDFVFGGYYPDNEVADHFWG 355
            |:.|..:...|.:.:          |.|.....||||:|::.|...|.:......:.|.|::...
  Fly   479 RINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEF 543

  Fly   356 SDTYLQDAHTWYIKMADRRPAWQA-LVGIFEAYT---WIGFILILIISWLFWFTLVMILPEPKYY 416
            |..:....    |.:.:::|:..: ||...:.::   ||..::.:.:..|..:.|....|..::
  Fly   544 SKPFKYQG----ITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRF- 603

  Fly   417 QQLSLTAIN-ALAVTISIAV-------------QERPICETTRLFFMALTLYGLNVVATYTSKM- 466
             :||.:..| ..|:.:|.||             :..|...:.|:..|....:.:.:||:||:.:
  Fly   604 -KLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLA 667

  Fly   467 -----------IATFQDPGYLHQLDELTEVVAAG----IPFGGHEESRDWFENDDDMWIFNGYNI 516
                       ::...|....:.::.||.....|    :.|....|..:.:...:    .|.|..
  Fly   668 AFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTME----ANNYAT 728

  Fly   517 SPEFIPQSK--NLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFS-SPVQMIMKAGFPFLFE 578
            :.:.|...|  .|.|..|.     |:|:....|...:::.|  ..:|. |...:.::.|.|:...
  Fly   729 AEQAIQDVKKGKLMAFIWD-----SSRLEYEASKDCELVTA--GELFGRSGYGIGLQKGSPWTDA 786

  Fly   579 MNSIIRLMRDVGIFQKIDADFRYNNTYLNRINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAA 643
            :...|....:.|..:|:|..:.::    ..:.:....|.:|...|..:::.|.|.::.||.....
  Fly   787 VTLAILEFHESGFMEKLDKQWIFH----GHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGV 847

  Fly   644 LTFIGELIIHRWRTQLVSTSEQQDRRSDKRRRRRRRRKPEKDN-RWQRQVQV------AP-VVRF 700
            ...|.|:|..:.:.:.....:.....:||.|....:||..:.: ..|||..|      || .:..
  Fly   848 GLIIIEVIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISL 912

  Fly   701 TPVKRRKVFQGQ 712
            ...|||....||
  Fly   913 AVDKRRYPRLGQ 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	28/128 (22%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	76/458 (17%)
		CaM_bdg_C0	854..882	CDD:402271	4/27 (15%)