Protein Alignment Ir60a and clumsy

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001036373.1
• Gene: clumsy / 35394
• FlyBaseID: FBgn0026255
• Length: 1002
• Species: Drosophila melanogaster
• Alignment Length: 653
• Identity: 120/653 - (18%)
• Similarity: 203/653 - (31%)
• Gaps: 184/653 - (28%)

  Fly   123 SDYNITNGTEDKGELILADNYVIVVDSVDRLKELMKKKIVEMRSW--NPGARFLVLFHNAT---- 181
            ||:::.|...|..|....:.....||. :|:|..|  .::....|  :.|...|.:|...|
  Fly   269 SDFHVKNVVHDWEEREKREGRYFKVDP-NRVKSQM--ILLNDAVWLFSKGLTELGIFEELTAPDL 330

  Fly   182 -CRNR---PLGVASNIFKDLMEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNVQSVGQCH 242
             ||.:   |.|      |.::|..    .|.....||...:...|...|....|.:.:.|.|...
  Fly   331 ECRRKKPWPFG------KRIIEFI----KARSEETSTGRIDFNENGQRSFFTLRFMELNSDGFLD 385

  Fly   243 DGKLYPNNAVVKASMQDYVS---------GFSPRNCTFFACSSISAPFV------EADCIL---- 288
            .....|.|.:      |.::         |....|.||...|.:.|||:      |.:.:.
  Fly   386 LATWDPVNGL------DVLNDDEESEKRVGQKLSNKTFIVSSRLGAPFLTLREPQEGEILTGNSR 444

  Fly   289 --GLEMRILGFMKNRLKFDVNQTCSLESRGEMDG--------PANWTGLL-----GKVQNNECDF 338
              |..:.::..:...|.|      ..|.|...||        ...|.|::     |......||.
  Fly   445 YEGYSIDLINEIAKMLNF------KFEFRMSPDGKYGALNKVTQTWDGIVRQLIDGNADLGICDL 503

  Fly   339 VFGGYYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQ-----ALVGIFEAYTWIGFILILII 398
            ....  ...:..|       :.....|..|.:...:|...     :.:..|....||......:.
  Fly   504 TMTS--SRRQAVD-------FTPPFMTLGISILFSKPPTPPTDLFSFLSPFSLDVWIYMGSAYLF 559

  Fly   399 SWLFWFTLVMILP----------EPKYYQQLSLTAINALAVTISIAVQE----RPICETTRLFFM 449
            ..|..|.|..:.|          ||:..:.: .:.:|...::|...:.:    .|...:|||...
  Fly   560 ISLLLFALARMAPDDWENPHPCKEPEEVENI-WSIMNTTWLSIGSLMGQGCDILPKAASTRLVTG 623

  Fly   450 ALTLYGLNVVATYTSKMIATFQDPGYLHQLDELTEV----------VAAGIPFGGHEESRDWFEN 504
            ....:.|.::.:||:.:.|...:....:.::...::          :|.|...|...:|.  |..
  Fly   624 MWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFFRDSN--FST 686

  Fly   505 DDDMW---------IFNGYN-ISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPL--------AD 551
            ...||         :|...| ...|.:.:.|||.|             :.|:|..        .|
  Fly   687 YQKMWTAMESASPSVFTKTNDEGVERVQKGKNLYA-------------FLMESTTLEYNVERKCD 738

  Fly   552 VI------------YAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRL-------MRDVGIFQKIDA 597
            ::            .|.|   |:||.:..:.|....|.|:..:..|       |...|..:|.|.
  Fly   739 LVQIGGWLDYKSYGIAMP---FNSPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGGNCEKSDE 800

  Fly   598 DFRYNNTYLNRINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTFIGELIIHRWRTQLVST 662
            |              ....||    |..|::.|.|.:|.:|...|.:....|.:   |..:.|:.
  Fly   801 D--------------GGDTPE----LGLENVGGVFLVLGLGLLSAMVLGCTEFL---WNVKSVAI 844

  Fly   663 SEQ 665
            .|:
  Fly   845 EEK 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
clumsy	NP_001036373.1	PBP1_iGluR_Kainate	26..396	CDD:107377	31/145 (21%)
		ANF_receptor	39..379	CDD:279440	27/122 (22%)
		PBP2_iGluR_Kainate	414..787	CDD:270432	69/406 (17%)
		Lig_chan	548..812	CDD:278489	52/300 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462630
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830