Protein Alignment Ir60a and GluRIIA

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_523484.2
• Gene: GluRIIA / 33788
• FlyBaseID: FBgn0004620
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 834
• Identity: 145/834 - (17%)
• Similarity: 246/834 - (29%)
• Gaps: 351/834 - (42%)

  Fly    95 EGFSK---LINEAVTNPGPPDREELFQMRVASDYNITNGTEDKGELILADNYVIVVDSVDR---- 152
            ||.::   |:|....|      .:..::|..:||              ||:|.|:....|.
  Fly   174 EGLARLQDLMNIQALN------SDYVKLRNLADY--------------ADDYRILWKETDETFHE 218

  Fly   153 -----------LKELMKKKI-----VEMRSWNPGARFLVLF--HNATCRN-------------RP 186
                       ||||:|..|     ...|:|     ||...  ||:..|:             |.
  Fly   219 QRIILDCEPKTLKELLKVSIDFKLQGPFRNW-----FLTHLDTHNSGLRDIYNEDFKANITSVRL 278

  Fly   187 LGVASNIFK---------------DLMEMFYVHRVALLYANSTMNYNLLVNDYY-SNVNCR---- 231
            ..|.:|.|:               ..|....::...:|:|:|..|....:..:: .|.:|.
  Fly   279 KVVDANPFERKKTRLTKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSSSP 343

  Fly   232 ------ILN--------------------VQSVGQCHDGKLYPNNAVVKASMQDYVSGFSPRNCT 270
                  |:|                    :...||    :::.|..:.|.::.:.:..::|.|
  Fly   344 WMLGAFIVNEMKTISEDDVEPHFKTENMKLDEYGQ----RIHFNLEIYKPTVNEPMMVWTPDN-- 402

  Fly   271 FFACSSISAPFVEADCILGLEMRILG-----------FMKNRLKFDV------------NQTCSL 312
                              |::.|:|.           |.:.|..:.|            ....:.
  Fly   403 ------------------GIKKRLLNLELESAGTTQDFSEQRKVYTVVTHYEEPYFMMKEDHENF 449

  Fly   313 ESRGEMDGPANWTGLLGKVQN-NECDFVF------GGYYPDNEVADHFWGSDTYLQDAHTWYIKM 370
            ..|.:.:|.|  ..|:.|:.. .|.|:.|      |.|.|:.:..|   |....|.|.|. .|.:
  Fly   450 RGREKYEGYA--VDLISKLSELMEFDYEFMIVNGNGKYNPETKQWD---GIIRKLIDHHA-QIGV 508

  Fly   371 AD------RR-------PAWQALVGI------------------FEAYTWI-----------GFI 393
            .|      ||       |..|..:.|                  |....||           .|:
  Fly   509 CDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLEPFAVEVWIYMIFAQLIMTLAFV 573

  Fly   394 LILIISWLFWFTLVMILPEPKYYQQLSLTAI----NALAVTISIAVQERPICE-----------T 443
            .|..:|:..|     :.|.|.......|..|    |:..:.:...:|:.  |:           |
  Fly   574 FIARLSYREW-----LPPNPAIQDPDELENIWNVNNSTWLMVGSIMQQG--CDILPRGPHMRILT 631

  Fly   444 TRLFFMALTLYGLNVVATYTSKMIATFQDPGYLHQLDELTEVVAAG-IPFG---GHEESRDWFEN 504
            ...:|.||.:     ::|||:.:.|......:...:..|.:::... :.||   |...|. :|..
  Fly   632 GMWWFFALMM-----LSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSL-FFSE 690

  Fly   505 DDDMWIFNGYNISPEFIPQ---SKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQ 566
            .:|......:|...:|.|.   |.|.|.|...::
  Fly   691 SNDTDYQRAWNQMKDFNPSAFTSTNKEGVARVRK------------------------------- 724

  Fly   567 MIMKAGFPFLFEMNSIIRLM---------------RDVGIFQKIDADFRYNNTY-------LNRI 609
              .|.|:.||.|..|:...:               :..|:...:.:|:|.|.:.       ...:
  Fly   725 --EKGGYAFLMETTSLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGEL 787

  Fly   610 NKMRPQF----------------PETAIVLTTEHLKGPFFILVVG-------------------- 638
            .||:.::                .|.:|:    .|.|.|.:|..|
  Fly   788 QKMKNKWWKNHNVTCDSYHEVDGDELSII----ELGGVFLVLAGGVLIGVILGIFEFLWNVQNVA 848

  Fly   639 -----SCWAALTFIGELI--IHRW-RTQLVSTSEQQDRRSDKRRRRRRRRKPEK 684
                 :.|.|  |..|||  :..| |.:.:..|...|:.|.:|....||...||
  Fly   849 VEERVTPWQA--FKAELIFALKFWVRKKPMRISSSSDKSSSRRSSGSRRSSKEK 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
GluRIIA	NP_523484.2	PBP1_iGluR_Kainate	33..404	CDD:107377	45/278 (16%)
		ANF_receptor	46..386	CDD:279440	42/240 (18%)
		PBP2_iGluR_Kainate	426..796	CDD:270432	73/421 (17%)
		Lig_chan	556..828	CDD:278489	53/321 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462628
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830