Protein Alignment Ir60a and Ir25a

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 743
• Identity: 139/743 - (18%)
• Similarity: 264/743 - (35%)
• Gaps: 212/743 - (28%)

  Fly    56 LDSFAQIFFFRNPKERFTRAYNLMLVHAFHLSSPADQIQEGFSKLINEAVTNPGPPDREELFQMR 120
            |:|....:|.||      .|::.:..:...:||..|.....|.|.:  |.|.    .|:.|..:|
  Fly   247 LESVKPAYFERN------FAWHAITQNEGEISSQRDNATIMFMKPM--AYTQ----YRDRLGLLR 299

  Fly   121 VASDYNITNGTEDKGELILADNYVIVVDSVDRLKELMKKKIVEMRSWNPGARFLVL--FHNATCR 183
              :.||:    .::.:|..|..:.:.:.|...:||::     :..:|.....:|..  |......
  Fly   300 --TTYNL----NEEPQLSSAFYFDLALRSFLTIKEML-----QSGAWPKDMEYLNCDDFQGGNTP 353

  Fly   184 NRPLGVASNIFK----------DLM----EMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILN 234
            .|.|.:.....|          ||:    :.|..|.    :....|:.|:|.....|:||.:
  Fly   354 QRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFNGHS----FMKFEMDINVLQIRGGSSVNSK--- 411

  Fly   235 VQSVGQCHDGKLYPNNAVVKASMQDYVSGFSPRNCT----FFACSSISAPFVEAD---------- 285
              |:|:...|  ..:..:||...|       .:|.|    :...:.:.|||:..|
  Fly   412 --SIGKWISG--LNSELIVKDEEQ-------MKNLTADTVYRIFTVVQAPFIMRDETAPKGYKGY 465

  Fly   286 CILGLEMRILGFMKNRLKFDVN-QTCSLESRGEMDGPANWTGLLGKVQNNECDFVFG--GYYPDN 347
            ||     .::..:...:.||.. |.......|.||....|.|::.|:.:.:.|...|  ....:.
  Fly   466 CI-----DLINEIAAIVHFDYTIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAER 525

  Fly   348 EVADHFWGSDTYLQDAHTWY----IKMADRRPAWQA----LVGIFEAYTWI----GFILILIISW 400
            |:...|         ...:|    |.:..:||:..:    .:.:.|...|:    .:.....:.|
  Fly   526 EIVIDF---------TVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMW 581

  Fly   401 LF--WFTLVMILPEPKYYQ-------------QLSLTAINALAVTISIAVQ---ERPICETTRLF 447
            :|  |        .|..||             :.:|.......:| |:..|   |.|...:.||.
  Fly   582 IFDRW--------SPYSYQNNREKYKDDEEKREFNLKECLWFCMT-SLTPQGGGEAPKNLSGRLV 637

  Fly   448 FMALTLYGLNVVATYTSKM-----IATFQDPGYLHQLDELT---EVVAAGIPFGGHEESRDWFE- 503
            .....|:|..::|:||:.:     ::....|  :..||:|.   :::.|  |..| ..:..:||
  Fly   638 AATWWLFGFIIIASYTANLAAFLTVSRLDTP--VESLDDLAKQYKILYA--PLNG-SSAMTYFER 697

  Fly   504 --NDDDMWIFNGYNISPEFIPQSKNLEAVKWGQRCI----LSNRMYT----------MQSPLADV 552
              |.:.|:    |.|..: :..:.:|.||:..:..:    :|:: ||          :.:.|.:.
  Fly   698 MSNIEQMF----YEIWKD-LSLNDSLTAVERSKLAVWDYPVSDK-YTKMWQAMQEAKLPATLDEA 756

  Fly   553 IYAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMRDVGIFQKIDADF-----------------R 600
            :....|:..::        ||.||.:...|..|.......|.:..:|                 :
  Fly   757 VARVRNSTAAT--------GFAFLGDATDIRYLQLTNCDLQVVGEEFSRKPYAIAVQQGSHLKDQ 813

  Fly   601 YNNTYLNRINKM--------------------RPQFPETAIVLTTEHLKGPFFILVVGSCWAALT 645
            :||..|..:||.                    :|:.....|  :.:::.|.|.::.||...|.:|
  Fly   814 FNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPEDQSDGI--SIQNIGGVFIVIFVGIGMACIT 876

  Fly   646 FIGELIIHRWR--TQLVSTSEQQDRRSD 671
            .:.|...:|:|  .:::..:|....||:
  Fly   877 LVFEYWWYRYRKNPRIIDVAEANAERSN 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	42/212 (20%)
		PBP2_iGluR_putative	438..836	CDD:270435	78/439 (18%)
		Lig_chan	565..870	CDD:278489	59/334 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463016
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830