Protein Alignment Ir60a and gria4b

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 676
• Identity: 120/676 - (17%)
• Similarity: 202/676 - (29%)
• Gaps: 279/676 - (41%)

  Fly    48 VWKAGVGCLDSFAQI--FFFRNPKERFTRAYNLMLVH---------AFHLSSPADQIQEGFSKLI 101
            ||...:|...|..||  .|.||..:.:|.....:.:|         .|:|....|.|:...|..:
Zfish    15 VWGLTMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAV 79

  Fly   102 NEA-----------------------------------VTNPGPPDREELFQMRVASDYNITNGT 131
            ..|                                   :|...|.:.|..|.:::....
Zfish    80 TNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCGALHISLITPSFPTEGESQFVLQLRPSI------ 138

  Fly   132 EDKGELI-LADNY-----VIVVDSVDR----LKELMKKKIVEMRSWNPGARFLVLFHNATCRNRP 186
              :|.|: |.|:|     |.:.|: ||    |:.:|:|  .....|...|..:..|::|:.|
Zfish   139 --RGALLSLLDHYDWNRFVFLYDT-DRGYSILQAIMEK--AGQNGWQVSAICVENFNDASYR--- 195

  Fly   187 LGVASNIFKDL---MEMFYVHRVALLYANSTMNYNLLVNDY-------YSNVNCRILNVQSVGQC 241
                 .:.:||   .|..:|..:.....|:.:...:.|..:       .:|:..:.:|::..  .
Zfish   196 -----QLLEDLDRRQEKTFVIDLEAERLNNMLEQIVSVGKHVKGYHYIMANLGFKDINLERF--M 253

  Fly   242 HDGKL--------YPNNAVV-------KASMQDYVSGFSPRNCTFFAC----------------- 274
            |.|..        :.|..|:       |...::|....:|...|....
Zfish   254 HGGANVTGFQLVDFSNPMVIKLMQRWNKLDQREYPGSDAPPKYTSALTYDGVMVMAEAFRNLRRQ 318

  Fly   275 -SSISAPFVEADCIL--------GLEM-------------------------------------- 292
             ..||...:..||:.        |::|
Zfish   319 KVDISRRGIAGDCLANPAAPWNQGIDMERTLKQVHLQGLTGNVQFDHYGRRVNYTMDVFELKSNG 383

  Fly   293 -RILGFMKNRLKFDV--------NQTCSLESRGE-----MDGP-----ANWTGLLGKVQNNECDF 338
             |.:|:..:..|..:        |:|..:|:|..     |:||     .||....|..|
Zfish   384 PRRIGYWNDADKLVLTQDHALLPNETSGMENRTVIVTTIMEGPYVMLKKNWEMYEGNEQ------ 442

  Fly   339 VFGGYYPD--NEVADH--FWGSDTYLQDAHTWYIKMADRRPAWQALVGIFEAYTWIGFILILIIS 399
             :.||..|  :|:|.|  |....:.:.|.     |...|.|         |...|.|.:..|:
Zfish   443 -YEGYCVDLASEIAKHIGFKYKISIVPDG-----KYGARDP---------ETKIWNGMVGELV-- 490

  Fly   400 WLFWFTLVMILPEPKYYQQLSLTAINALAVTISIAVQERPICETTRLFFMALTLYGLNVVATYTS 464
              :....:.:.|       |::|.:....:..|     :|        ||:|   |::::.....
Zfish   491 --YGKAEIAVAP-------LTITLVREEVIDFS-----KP--------FMSL---GISIMIKKPQ 530

  Fly   465 KMIATFQDPGYLHQLDELTE-----VVAAGI-------------PFGGH----EESRDWFEND-- 505
            |     ..||....||.|..     :|.|.|             |:..|    ||..|...:|
Zfish   531 K-----SKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEEGTDGLPSDQP 590

  Fly   506 -DDMWIFN------------GYNISP 518
             ::..|||            |.:|||
Zfish   591 PNEFGIFNSLWFSLGAFMQQGCDISP 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
gria4b	NP_997917.2	Periplasmic_Binding_Protein_Type_1	28..398	CDD:324556	59/390 (15%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	54/256 (21%)
		Lig_chan	546..827	CDD:306551	16/71 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830