Protein Alignment Ir60a and GluRIIE

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 838
• Identity: 159/838 - (18%)
• Similarity: 286/838 - (34%)
• Gaps: 249/838 - (29%)

  Fly    25 VNLSNETANTVIFMLPEKDLGPDVWKA-GVGC--LDS-FAQIFFFRNPKERFTRAYNLMLVHAF- 84
            ::::|:...|.:..|.|:....|.::: |..|  |:: .|.:|   .|..|.|..:.:.:..|.
  Fly    60 IDVANQEVGTSLTSLKEEVNYGDAYQSYGKLCRMLETGIAGVF---GPSSRHTAVHLMSICDAMD 121

  Fly    85 --HLSSPADQIQEGFSKLINEAVTNPGPPDREE--------------LFQMRVASDYNITNGTE- 132
              |:.|...:..|||:       .:|.|.|..:              :|....|...||.|...
  Fly   122 IPHIYSYMSENAEGFN-------LHPHPADLAKALYSLITEFNWTRFIFLYESAEYLNILNELTT 179

  Fly   133 ---DKGELIL----------------------ADNYVIVVDSVDRLKELMKK------------- 159
               ..|.:|.                      .||.::||.|.:.:.|.:.:
  Fly   180 MLGKSGTVITVLRYDMQLNGNYKQVLRRVRKSVDNRIVVVGSSETMPEFLNQAQQVGIINEDYKY 244

  Fly   160 --------------------KIVEMRSWNP---GARFLVL----------FHNATCRNRPLGVAS 191
                                .|..:|.::|   ..:.|::          |.|.:|   |:.|..
  Fly   245 IIGNLDFHSFDLEEYKYSEANITGLRLFSPEKMAVKELLMKLGYPTDQDEFRNGSC---PITVEM 306

  Fly   192 NIFKDLMEMFYVHRVALLY-----------------ANSTMNY--------NLLVNDYYSNVNCR 231
            .:..|.:::|......|.:                 .:|..||        .||....|...|.|
  Fly   307 ALTYDAVQLFAQTLKNLPFKPMPQNCSQRTESVRDDGSSFKNYMRTLRLTDRLLTGPIYFEGNVR 371

  Fly   232 ------ILNVQ-----SVGQCHDGKLY-PNNAVVKASMQDYVSGFSPRNCTFFACSSIS----AP 280
                  ::.:|     .||...:.:.| |.......:..|.|.. |..|.||....|:.    |.
  Fly   372 KGYHLDVIELQPSGIVKVGTWDEDRQYRPQRLAPTTAQFDSVDN-SLANKTFIILLSVPNKPYAQ 435

  Fly   281 FVEADCIL-------GLEMRILGFMKNRLKFDVNQTCSLESRGEMDGPAN-WTGLLGKVQNNECD 337
            .||....|       |..:.::..:.::|.|:..........|..:...| .||:|.::.....|
  Fly   436 LVETYKQLEGNSQYEGYGVDLIKELADKLGFNFTFVNGGNDYGSYNKSTNESTGMLREIMTGRAD 500

  Fly   338 FVFGG--YYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQALVGIFEAYTW--IGFILILII 398
            .....  ...:.|.|..|......|..| ..|:|.....|.....:..|....|  :||..:.:.
  Fly   501 LAITDLTITSEREQALDFTIPFMNLGIA-ILYLKPQKATPELFTFMDPFSEEVWWFLGFSFLGVS 564

  Fly   399 SWLFWFTLVMILP-----------EPKYYQQLSLTAINALAVTISIAVQE----RPICETTRLFF 448
              |.:|.|..:.|           ||:..:. ..|..|::..|....:|:    .|...:||...
  Fly   565 --LSFFILGRLSPSEWDNPYPCIEEPEELEN-QFTLGNSIWFTTGALLQQGSEIGPKALSTRTVA 626

  Fly   449 MALTLYGLNVVATYTSKMIA--TFQDP-GYLHQLDELTEVVAAGIPFGGHE--ESRDWF-----E 503
            .....:.|.||::||:.:.|  |.:.| ..::.:|:|.: ...|:.:|..:  .:|::|     |
  Fly   627 SFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLAD-NKDGVVYGAKKTGSTRNFFMTSAEE 690

  Fly   504 NDDDMWIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQ-- 566
            ....|..|...|  |:::.:. |:|.|         ||:.|      :..|||  .:.|:.::
  Fly   691 RYKKMNKFMSEN--PQYLTED-NMEGV---------NRVKT------NTHYAF--LMESTSIEYN 735

  Fly   567 --------------------MIMKAGFPFLFEMNSIIRLMRDVGIFQKIDADFRYNNTYLNRIN- 610
                                :.|:..:|...:.|:.:..:::.|:.:|:      .|.:.|.:.
  Fly   736 TKRECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKM------KNKWWNEVGT 794

  Fly   611 ---KMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTFIGELII------HRWRTQL 659
               ..:...|: |..|...:|:|.||:|:||||.|.|..|...::      |.:|..|
  Fly   795 GICATKEDAPD-ATPLDMNNLEGVFFVLLVGSCCALLYGIISWVLFVMKKAHHYRVPL 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	42..396	CDD:107377	58/348 (17%)
		ANF_receptor	51..382	CDD:279440	55/334 (16%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	77/401 (19%)
		Lig_chan	551..824	CDD:278489	60/303 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740