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Protein Alignment Ir60a and Grik1

DIOPT Version :9

Sequence 1:	NP_611901.1	Gene:	Ir60a / 37881	FlyBaseID:	FBgn0034994	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus

Alignment Length:	970	Identity:	171/970 - (17%)
Similarity:	299/970 - (30%)	Gaps:	372/970 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWCNNPGLIIIIFL--------GQILNLCQGIVNLSNETANT--VIF------------MLPEKD 43
            :|..:....::.||        .|:|.:......:.||..|.  :.|            ::|...
  Rat    12 LWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTT 76

  Fly    44 LGPDVWKAGVGCLDSFAQIFFFRNPKERFTRAYNLMLVHAFHLSSPADQIQEGFSKLINEAVTNP 108
            |..|:.:  :...|||          |...||.:.:.:....|..|:........:.|..|:..|
  Rat    77 LTYDIQR--INLFDSF----------EASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVP 129

  Fly   109 --------GPPDREELFQMRVASDY-NITNGTEDKGELILADNY----VIVVDSVD--RLKELMK 158
                    ...|..:||.:.:..|| .|:....|   |:|..|:    |:..||..  ||:||:|
  Rat   130 HIQTRWKHPSVDSRDLFYINLYPDYAAISRAVLD---LVLYYNWKTVTVVYEDSTGLIRLQELIK 191

  Fly   159 K--------KIVEMRSWNPGAR-----------FLVLFHNATCRNRPLGVASNIFKDLMEM---- 200
            .        ||.::...|..|:           |.|:|   .|.:.   .|:.|.|.::.|
  Rat   192 APSRYNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIF---DCSHE---TAAEILKQILFMGMMT 250

  Fly   201 FYVHRVALLYANSTMN-YNLLVNDY-YSNVNC---RILNV-----------------QSVGQCHD 243
            .|.|     |..:|:: :.|.:..| ||.||.   |:||:                 |:..:...
  Rat   251 EYYH-----YFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPET 310

  Fly   244 GKLYPNNAVVKASMQD--YVSGFSPRNCTFFACSSISA----PFVEADCILGLEMRILGFMKNRL 302
            |.|........|.|.|  |:...:....:....||:..    |:       .|..|.:..:|.
  Rat   311 GLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPW-------RLGPRFMNLIKE-- 366

  Fly   303 KFDVNQTCSLESRGEMDGPANWTGLLGKVQNNECDFVFGGYYPD-------------NEVADH-- 352
                               |.|.||.|::..|:.|.:...:..|             .||:.|
  Rat   367 -------------------ARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLY 412

  Fly   353 -------FWGSD----------------------------TYLQDAHTWYIKMADRRPAWQALVG 382
                   .|.|:                            |.|::.:..|      |.:.:.|.|
  Rat   413 KVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMY------RKSDKPLYG 471

  Fly   383 --IFEAYTWIGFILILIISWLFWFTL-VMILPEPKYYQQLSLTAINALAVTISIAVQERPICETT 444
              .||.|.   ..|:..:|.:..|.. |.::|:.||..|......|.:...:        |....
  Rat   472 NDRFEGYC---LDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKEL--------IDHRA 525

  Fly   445 RLFFMALTLYGLNVVATYTSKMIATFQ------------------DPGYLHQLDELTE------- 484
            .|....||:       ||..:.:..|.                  :||....|:.|:.
  Rat   526 DLAVAPLTI-------TYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVL 583

  Fly   485 -----------VVAAGIPFGGHEESRDWFE----NDDDMWIFNGYNI--------------SPEF 520
                       |:|...|:       :|:.    |.|...:.|.:.:              ..|.
  Rat   584 LACLGVSCVLFVIARFTPY-------EWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSEL 641

  Fly   521 IPQSKNLEAVK--WGQRCILSNRMYT-----------MQSPL--AD------------------- 551
            :|::.:...|.  |....::....||           |:||:  ||
  Rat   642 MPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTM 706

  Fly   552 ------------VIYAFPNNVFSSP--------VQMIMKAGFPFLFEMNSIIRL----------- 585
                        .::||.::...|.        :|.::...:..|.|..||..:
  Rat   707 TFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIG 771

  Fly   586 ----MRDVGIFQKIDADFRYNNTYL-------NRINKMRPQF------PE----TAIVLTTEHLK 629
                .:..|:...|.:.:|...|..       .:::.|:.::      ||    .|..|..|::.
  Rat   772 GLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIG 836

  Fly   630 GPFFILVVGSCWAALTFIGELIIHRWRTQLVSTSEQQDRRSDKR---RRRRRRRKPEKDN 686
            |.|.:|..|...:....|||.:   ::::..:..||:.:.|..|   |.:.|....:|::
  Rat   837 GIFIVLAAGLVLSVFVAIGEFL---YKSRKNNDVEQKGKSSRLRFYFRNKVRFHGSKKES 893

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.