Protein Alignment Ir60a and GRID2

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_011530195.2
• Gene: GRID2 / 2895
• HGNCID: 4576
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 676
• Identity: 127/676 - (18%)
• Similarity: 237/676 - (35%)
• Gaps: 182/676 - (26%)

  Fly   101 INEAVTNPGPPDREELFQMRVASDYNITNGTEDKGELILADNYVIVVDSVDRLKELMKKKIVEMR 165
            |:..:.:|..|         .|.:..|:|              :.:.|:|..|.....||: |.|
Human   317 ISSTLCDPKDP---------FAQNMEISN--------------LYIYDTVLLLANAFHKKL-EDR 357

  Fly   166 SWNPGARFLVLFHNATCRNRPLGVASNIFKDLMEMFYVHRVALLY---------ANSTMNYNLLV 221
            .|:..|....:..|    ::|....    :.::|......|:.|.         .|..:::.:|.
Human   358 KWHSMASLSCIRKN----SKPWQGG----RSMLETIKKGGVSGLTGELEFGENGGNPNVHFEILG 414

  Fly   222 NDYYSNVNCRILNVQSV-GQCHDGKLYP-----------NNAVVKASMQDYVSGFSPRNCTFFAC 274
            .:|...:...:...:.: .|...||::|           |.::....:::.:.|...|..|.
Human   415 TNYGEELGRGVRKNERIRPQGSTGKIWPQLGCWNPVTGLNGSLTDKKLENNMRGVVLRVVTV--- 476

  Fly   275 SSISAPFV-EADCILGLEMRILGF-------MKNRLKFDVNQTCSLESR-GEMDGPANWTGLLGK 330
              :..||| .::.:||...:..||       :.|.|.|:.....:.:.: |.......|.||:|:
Human   477 --LEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGE 539

  Fly   331 VQNNECDFVFGG--YYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQALVGIFEAYTW---- 389
            :.....|.....  ..||.|....|  :..|:..:....::.|::.....|.:..|:...|
Human   540 LVFKRADIGISALTITPDRENVVDF--TTRYMDYSVGVLLRRAEKTVDMFACLAPFDLSLWACIA 602

  Fly   390 -----IGFILILIISWLFWFTLVMILPEPKYYQQLSLTA---INALAVTISIAVQ---ERPICE- 442
                 :| :|:.:::||          .|...|..|:|:   .|::.......||   |.|...
Human   603 GTVLLVG-LLVYLLNWL----------NPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTL 656

  Fly   443 TTRLFFMALTLYGLNVVATYTSKMIA---------TFQDPGYLHQLDELTEVVAAGIPFGGHEES 498
            .||:...|..|:.|.|:::||:.:.|         :.|.   |..|.:.||     ||:|...:|
Human   657 ATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQS---LQDLSKQTE-----IPYGTVLDS 713

  Fly   499 RDW----------FEND---DDMW-IFNGYNISPEFIPQSK-NLEAVKWGQRCILSNRMYTMQSP 548
            ..:          ||.|   ..|| :.|..|.|...:.:|: .::.||:|      |..:...:.
Human   714 AVYEHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYG------NYAFVWDAA 772

  Fly   549 LADVI---------YAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMRDVGIFQKIDADFRYNNT 604
            :.:.:         |...|.|......:.::.|.|:           |||  |.:...:.:.|..
Human   773 VLEYVAINDPDCSFYTIGNTVADRGYGIALQHGSPY-----------RDV--FSQRILELQQNGD 824

  Fly   605 YLNRINKMRPQFPETAI-----------VLTTEHLKGPFFILVVG---SCWAALTFIGELIIHRW 655
            .....:|..|:..:..:           .|..:...|.|.||..|   ||:.|:       :..|
Human   825 MDILKHKWWPKNGQCDLYSSVDTKQKGGALDIKSFAGVFCILAAGIVLSCFIAM-------LETW 882

  Fly   656 RTQLVST---SEQQDRRSDKRRRRRR 678
            ..:...:   |::.|:..|.....||
Human   883 WNKRKGSRVPSKEDDKEIDLEHLHRR 908

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156070
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740