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Protein Alignment Ir60a and Grin2b

DIOPT Version :9

Sequence 1:	NP_611901.1	Gene:	Ir60a / 37881	FlyBaseID:	FBgn0034994	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_036706.1	Gene:	Grin2b / 24410	RGDID:	2738	Length:	1482	Species:	Rattus norvegicus

Alignment Length:	487	Identity:	82/487 - (16%)
Similarity:	168/487 - (34%)	Gaps:	125/487 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 VQSV----GQCHDGKLYPNNAVVKASMQDYVSGFSPRNCTFFACSSISAPFVEADCILGLEMRIL 295
            |:||    |.|....:.....::..:..|...|:..:.|..|             ||     .||
  Rat   419 VESVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGF-------------CI-----DIL 465

  Fly   296 GFMKNRLKFDVNQTCSLESRGEMDGPAN--WTGLLGKVQNNECDFVFGGYYPDNEVADHFWGSDT 358
            ..:...:||..:  ..|.:.|:.....|  |.|::|:|.........|....:.|.::....|..
  Rat   466 KKISKSVKFTYD--LYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVP 528

  Fly   359 YLQDAHTWYIKMADRRPAWQALVGIFEAYTWI-GFILILIISWLFWFTLVMILP----------- 411
            :::...:..:..::...:..|.:..|.|..|: .|:::||:|.:..|......|
  Rat   529 FIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGR 593

  Fly   412 ---EPKYYQQLSLTAINALAVTISIAVQERPICETTRLFFMALTLYGLNVVATYTSKMIATFQDP 473
               .|.:....::..:..|....|:.|| .|...|:::.......:.:..:|:||:.:.|.....
  Rat   594 EPGGPSFTIGKAIWLLWGLVFNNSVPVQ-NPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQE 657

  Fly   474 GYLHQLDELTEVVAAGIPFGGHEESRDWFENDDDMWIFNGYNISPEF----IPQSKNLEAV---- 530
            .|:.|:..|::               ..|:..:|        .||.|    :|.......:
  Rat   658 EYVDQVSGLSD---------------KKFQRPND--------FSPPFRFGTVPNGSTERNIRNNY 699

  Fly   531 --------KWGQR----CILSNRMYTMQSPLAD---------------VIYAFPNNVFSSPVQMI 568
                    |:.||    .:||.:...:.:.:.|               ::......||:|
  Rat   700 AEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFAS----- 759

  Fly   569 MKAGFPFLFEMNS---------IIRLMRDVGIFQKIDADFRYNNTYLNRINKMRPQFPETAIVLT 624
              .|:....:.:|         |::|..| |..::::|.:.....:..:...|..|       |.
  Rat   760 --TGYGIAIQKDSGWKRQVDLAILQLFGD-GEMEELEALWLTGICHNEKNEVMSSQ-------LD 814

  Fly   625 TEHLKGPFFILVVGSCWAALTFIGELIIHRWR 656
            .:::.|.|::|......:.:|||.|.:.: |:
  Rat   815 IDNMAGVFYMLGAAMALSLITFICEHLFY-WQ 845

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.