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Protein Alignment Ir60a and Grin2a

DIOPT Version :9

Sequence 1:	NP_611901.1	Gene:	Ir60a / 37881	FlyBaseID:	FBgn0034994	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_036705.3	Gene:	Grin2a / 24409	RGDID:	2737	Length:	1464	Species:	Rattus norvegicus

Alignment Length:	678	Identity:	112/678 - (16%)
Similarity:	232/678 - (34%)	Gaps:	193/678 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 TEDKGELILA----------DNYVIVVDSVDRLKELMKKKI------VEMRSWNPGARFLVLFHN 179
            ::|:..|||:          |.:.||...|....||:.|:.      |....|:         ::
  Rat   232 SKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWD---------YS 287

  Fly   180 ATCRNRP-LGVASNIFKDLMEMF-YV------------------HRVALLYANSTMN-YNLLVND 223
            ...|.|. ||:.:.....::|.| |:                  |.:.....|.|.: .:|...:
  Rat   288 LEARVRDGLGILTTAASSMLEKFSYIPEAKASCYGQAEKPETPLHTLHQFMVNVTWDGKDLSFTE 352

  Fly   224 YYSNVNCRILNV--------QSVGQCHDGKLYPNNAVVKASMQDYVSGFSPRNCTFFACS----- 275
            ....|:.|::.:        :.||:..:..|...:||            .||..:|..|.
  Rat   353 EGYQVHPRLVVIVLNKDREWEKVGKWENQTLSLRHAV------------WPRYKSFSDCEPDDNH 405

  Fly   276 -SI----SAPFVEAD----------------------------------CILGLEMRILGFMKNR 301
             ||    .||||..:                                  |..|..:.||..:...
  Rat   406 LSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRT 470

  Fly   302 LKFDVNQTCSLESRGEMDGPAN--WTGLLGKVQNNECDFVFGGYYPDNEVADHFWGSDTYLQDAH 364
            :||..:  ..|.:.|:.....|  |.|::|:|.........|....:.|.::....|..:::...
  Rat   471 VKFTYD--LYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGI 533

  Fly   365 TWYIKMADRRPAWQALVGIFEAYTWI-GFILILIISWLFWFTLVMILP--------------EPK 414
            :..:..::...:..|.:..|.|..|: .|:::||:|.:..|......|              .|.
  Rat   534 SVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPS 598

  Fly   415 YYQQLSLTAINALAVTISIAVQERPICETTRLFFMALTLYGLNVVATYTSKMIATFQDPGYLHQL 479
            :....::..:..|....|:.|| .|...|:::.......:.:..:|:||:.:.|......::.|:
  Rat   599 FTIGKAIWLLWGLVFNNSVPVQ-NPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQV 662

  Fly   480 DELTE------------VVAAGIPFGGHEESRDWFENDDDMWIFNGYNISPEFIPQSKN------ 526
            ..|::            .....:|.|..|.:           |.|.|....:::.:...
  Rat   663 TGLSDKKFQRPHDYSPPFRFGTVPNGSTERN-----------IRNNYPYMHQYMTRFNQRGVEDA 716

  Fly   527 LEAVKWGQ-------RCILSN--------RMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFL 576
            |.::|.|:       ..:|:.        ::.|:.|.     |.|....:.    :.::.|.|:.
  Rat   717 LVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSG-----YIFATTGYG----IALQKGSPWK 772

  Fly   577 FEMN-SIIRLMRDVGIFQKIDADFRYNNTYLNRINKMRPQFPETAIVLTTEHLKGPFFILVVGSC 640
            .::: ::::.:.| |..::::..:.....:..:...|..|       |..:::.|.|::|.....
  Rat   773 RQIDLALLQFVGD-GEMEELETLWLTGICHNEKNEVMSSQ-------LDIDNMAGVFYMLAAAMA 829

  Fly   641 WAALTFIGELIIHRWRTQLVSTSEQQDR 668
            .:.:|||.|.:.: |:.:...|....||
  Rat   830 LSLITFIWEHLFY-WKLRFCFTGVCSDR 856

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.