DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir60a and W02A2.5

DIOPT Version :9

Sequence 1:	NP_611901.1	Gene:	Ir60a / 37881	FlyBaseID:	FBgn0034994	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_502564.2	Gene:	W02A2.5 / 189098	WormBaseID:	WBGene00012190	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	507	Identity:	90/507 - (17%)
Similarity:	159/507 - (31%)	Gaps:	152/507 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 NCTFFACSSI--SAPFVEADCILGLEMRILGFMKNRLKFDVNQTCSLESRGEMD-----GPANWT 325
            ||..|....:  ..||.      |..|.:|..:.:.||:::....:....|.:|     ....|:
Worm    21 NCPLFPTLDVILQCPFP------GWTMEVLKMITDSLKWEIIPVVTPTIVGGLDWGTLQKNGTWS 79

  Fly   326 GLLGKVQNNECDFVFGGYYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQALVGIFEAYT-- 388
            |:||.:||...|.| ...|...:..:.::.....:.:....::...........|...|:.::
Worm    80 GVLGYLQNGTADAV-ALMYQKTDTRNEYFEYSYPVTNVQPVFVARKKTETLGSVLWNAFKPFSVE 143

  Fly   389 -WIGFILILIIS----------------------W-LFWFTLVMILPEPKYYQQLSLTAINALAV 429
             |:..:..|:::                      | :.|..:.:.|.| |....|..|....:.:
Worm   144 VWLCLLASLVLNLLIMIAISGIEFKLLFRSRFRPWEMLWHVVQLQLDE-KSDDMLFYTLSGNIVL 207

  Fly   430 TISIAVQERPICETTRLFFMALTLYGLNVVATYTSKMIATFQDPGYLHQLDELTEVVAAGIPFGG 494
            .:...:|...:.|..:         |:.:.|..||.....|.:      .||:.:::.
Worm   208 FVFALLQSGILIEVYK---------GMLLTALITSNGDNPFAN------ADEMIKLIG------- 250

  Fly   495 HEESRDWFENDDDMWIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPL---------A 550
             |:......|....|.|:....|               .|:..:|.|..|..:|:         .
Worm   251 -EKKYHLTTNYMGNWYFDDLQHS---------------DQQHFVSLRAATASNPVIPAASVSAAL 299

  Fly   551 DVI----YAFPNNVFSSPVQM--------IMKAGFP-----FLFEMNSIIRLMRDVGIFQKIDAD 598
            |::    |.:|....|..:||        .:..|.|     |:|..|           |..| |:
Worm   300 DLVDSGKYIYPIQQDSLAMQMSKERCNYVYVSDGMPQVSSFFVFTKN-----------FSGI-AE 352

  Fly   599 F------------RYNNTYLNRINKM---------RPQFPETAIVLTTEHLKGPFFILVVGSCWA 642
            |            |..|.|.|...|:         .|...:....|..|.:.|.|.|..:|...:
Worm   353 FNTQIIMNQAFIQRTFNKYFNEGFKLGFIPKCEVTEPTASDATKPLDIESVIGVFTIGALGVAAS 417

  Fly   643 ALTFIGELIIHRWRTQLVSTSEQQDRRSDKRRRRRRRRKPEKDNRWQRQVQV 694
            .:.|:.| |.|.|..::::             ||.|.|.|.......|..|:
Worm   418 LMVFVFE-IYHYWHVRILA-------------RRARMRDPWNVRNLARIAQI 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
W02A2.5	NP_502564.2	Lig_chan-Glu_bd	<36..86	CDD:214911	12/55 (22%)
W02A2.5	NP_502564.2	Periplasmic_Binding_Protein_Type_2	<74..>124	CDD:304360	9/50 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900