Protein Alignment Ir60a and Grin2c

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 587
• Identity: 98/587 - (16%)
• Similarity: 198/587 - (33%)
• Gaps: 144/587 - (24%)

  Fly   182 CRNRPLGVASNIFKDLMEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNV------QSVGQ 240
            ||:.|..|:     ...|.||.|.:.:.:.....:::  ...|.......::.:      :.||:
Mouse   379 CRSHPGPVS-----PAREAFYRHLLNVTWEGRDFSFS--PGGYLVQPTMVVIALNRHRLWEMVGR 436

  Fly   241 CHDGKLYPNNAV---VKASMQDYV-------------------------SGFSPR--------NC 269
            ...|.||....|   ...|:|..|                         .|..|.        |.
Mouse   437 WDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPNTVPCRRQSNH 501

  Fly   270 TFFACSSISAPFVEADCILGLEMRILGFMKNRLKFD------VNQTCSLESRGEMDGPANWTGLL 328
            ||  .|....|:.:. |..|..:.||..:...:||.      .|.......||.      |.|::
Mouse   502 TF--SSGDITPYTKL-CCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRVRGV------WNGMI 557

  Fly   329 GKVQNNECDFVFGGYYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQALVGIFEAYTWI-GF 392
            |:|.....|...|....:.|.::....|..:::...:..:..::...:..|.:..:....|: .|
Mouse   558 GEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMF 622

  Fly   393 ILILIISWLFWFTLVMILPEPKYYQQL---------------SLTAINALAVTISIAVQERPICE 442
            ::.|.:..:..|......| ..|.|.|               |:..:.||....|:.: |.|...
Mouse   623 VMCLTVVAITVFMFEYFSP-VSYNQNLTKGKKSGGPSFTIGKSVWLLWALVFNNSVPI-ENPRGT 685

  Fly   443 TTRLFFMALTLYGLNVVATYTSKMIATFQDPGYLHQLDELTEVVAAGIPFGGHEESRDWFENDDD 507
            |:::..:....:.:..:|:||:.:.|......|:..:..|::               ..|:...|
Mouse   686 TSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSD---------------KKFQRPQD 735

  Fly   508 MW-------IFNG---YNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFS 562
            .:       :.||   .||...:  :..:...||:.||.: .:.:.:::.....|.......::.
Mouse   736 QYPPFRFGTVPNGSTERNIRSNY--RDMHTHMVKFNQRSV-EDALTSLKMGARHVSRKLDAFIYD 797

  Fly   563 SPV-------------------QMIMKAGFPFLFEMNSIIRLMRDVGIFQKI-DADFRYNNTYL- 606
            :.|                   ::....|:....:.:|..:...|:.:.|.: |.:.:...|..
Mouse   798 AAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWL 862

  Fly   607 -----NRINKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTFIGELIIHRWRTQ-LVSTSEQ 665
                 |..|::      .:..|..:::.|.|::|:|....|.|.|..|.::: |:.: .|.:|.|
Mouse   863 SGICHNEKNEV------MSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVY-WKLRHSVPSSSQ 920

  Fly   666 QD 667
            .|
Mouse   921 LD 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	14/73 (19%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	64/434 (15%)
		NMDAR2_C	905..>980	CDD:371139	5/19 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830