Protein Alignment Ir60a and Grik5

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 722
• Identity: 136/722 - (18%)
• Similarity: 235/722 - (32%)
• Gaps: 222/722 - (30%)

  Fly    77 NLMLVHAFHLSSPADQIQEGFSKLIN-------EAVTNPGPPDREELFQMRVASDYNITNGTEDK 134
            |::....|:.|.|   ....|.:.:|       ||.|.|||.                      .
Mouse   286 NILGFSMFNTSHP---FYPEFVRSLNMSWRENCEASTYPGPA----------------------L 325

  Fly   135 GELILADNYVIVVDSVDRLKELMKKKIVEMRSWNPGARFLVLFHNATCRNRPLGVAS-NIFKDLM 198
            ...::.|...:||.:|..|.          ||...|.             :||...| ||:.
Mouse   326 SAALMFDAVHVVVSAVRELN----------RSQEIGV-------------KPLACTSANIWP--- 364

  Fly   199 EMFYVHRVALLYANSTMNYNLLVNDY--------------YSNVNCRILNVQSVGQCHDGKLYPN 249
                       :..|.|||..:| :|              .:|...|||.....|....|..|.|
Mouse   365 -----------HGTSLMNYLRMV-EYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSN 417

  Fly   250 NAV-VKASMQDYVSGFSPRNCTFFACSSISAPFV----EADCILGLEMRILGFMKNRLKFDVNQT 309
            ..: :.|:..|.....:..|.|....:.:..|:|    ....:.|.| |..||..:.|: ::.:.
Mouse   418 RTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNE-RFEGFCVDMLR-ELAEL 480

  Fly   310 CSLESR---------GEMDGPANWTGLLGKVQNNE-CDFVFGGY--YPDNEVADHFWGSDTYLQD 362
            .....|         |..:...:|||::|::.|.: .|.....:  ..:.|....|......|..
Mouse   481 LRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRQKADLAVAAFTITAEREKVIDFSKPFMTLGI 545

  Fly   363 AHTWYIKMADRRPAWQALVGIFEAYTWIGFILI--LIISWLF----------WFTLVMILPEPKY 415
            :..:.:.|. |:|.:.:.:..|....|: |:|:  |.:|.:.          |:.....|....:
Mouse   546 SILYRVHMG-RKPGYFSFLDPFSPAVWL-FMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPH 608

  Fly   416 YQQLSLTAINALAVTISIAVQE----RPICETTRLFFMALTLYGLNVVATYTSKMIA-----TFQ 471
            ..:...|..|:|...:...:|:    .|...:||........:.|.::::||:.:.|     ..:
Mouse   609 ILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRME 673

  Fly   472 DPGYLHQLDELTE-------VVAAGIPFGGHEESRDWFENDDDMWIFNGYNISPEFIPQSKNLEA 529
            .|  :...|:|.:       .:.||......:.||  ::....||.:
Mouse   674 VP--VESADDLADQTNIEYGTIHAGSTMTFFQNSR--YQTYQRMWNY------------------ 716

  Fly   530 VKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFE--MNSIIRLM------ 586
                           |||....|   |..:. ...:..::.:.:.||.|  ||...|.:
Mouse   717 ---------------MQSKQPSV---FVKST-EEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQ 762

  Fly   587 -------RDVGIFQKIDADFRYNNTYL-------NRINKMRPQFPE----------TAIVLTTEH 627
                   :..||...:.:.||...|..       ||:..::.::.|          .|..|..|:
Mouse   763 IGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWWEGGRCPKEEDHRAKGLGMEN 827

  Fly   628 LKGPFFILVVGSCWAALTFIGELIIHRWRTQLVSTSEQ--------QDRR----SDKRRRRRRRR 680
            :.|.|.:|:.|...|....:.|.|   |.|:..:.||:        |:.|    ..|..|.||||
Mouse   828 IGGIFVVLICGLIIAVFVAVMEFI---WSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRR 889

  Fly   681 KPEKDNR 687
            :|...:|
Mouse   890 RPGGPSR 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	39/200 (20%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:473866	70/415 (17%)