Protein Alignment Ir60a and Grik3

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001074566.1
• Gene: Grik3 / 14807
• MGIID: 95816
• Length: 919
• Species: Mus musculus
• Alignment Length: 865
• Identity: 153/865 - (17%)
• Similarity: 283/865 - (32%)
• Gaps: 315/865 - (36%)

  Fly    73 TRAYNLMLVHAFHLSSPA-----DQIQEGFSKLIN----------EAVTNP------------GP 110
            |..|::..:| ||.|..|     ||:..|...:..          :::.|.            .|
Mouse    78 TLTYDIQRIH-FHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHIQLRWKHHP 141

  Fly   111 PDREELFQMRVASDY-NITNGTEDKGELILADNYVIVVD---SVDRLKEL--------MKKKIVE 163
            .|.::.|.:.:..|| ::::...|..:.:...:..:|.|   .:.||:||        ::.||.:
Mouse   142 LDNKDTFYVNLYPDYASLSHAILDLVQSLKWRSATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQ 206

  Fly   164 -----------MRSWNPGARFLVLFHNATCRNRPLGVASNIFKDLMEM----FYVHRVALLYANS 213
                       ::....|..|.::|   .|.:.   :|:.|.|..|.|    .|.|     :..:
Mouse   207 LPIDSDDSRPLLKEMKRGREFRIIF---DCSHT---MAAQILKQAMAMGMMTEYYH-----FIFT 260

  Fly   214 TMN-YNLLVNDY-YSNVNC---RILNVQSVG---------------------------------- 239
            |:: |.|.:..| ||.||.   |||||.:..
Mouse   261 TLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWAMERLQAAPRAESGLLDGVMMTDAAL 325

  Fly   240 -----------------------QCHDGKLYP-----NNAVVKASMQ------------------ 258
                                   |||..|.:.     .|.:.:|..:
Mouse   326 LYDAVHIVSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDF 390

  Fly   259 --DYVS-------------------------GFSPR------NCTFFACSSISAPFV-------- 282
              |.:|                         |..|.      |.:....:.:..|||
Mouse   391 DLDIISLKEDGLEKVGVWSPADGLNITEVAKGRGPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRT 455

  Fly   283 -------EADCILGLE--MRILGFMKNRLKFDVNQTCSLESR-------GEMDGPANWTGLLGKV 331
                   |..||..|:  ..||||             |.|.|       |..|....|.|::.::
Mouse   456 LYGNDRFEGYCIDLLKELAHILGF-------------SYEIRLVEDGKYGAQDDKGQWNGMVKEL 507

  Fly   332 QNNECDFVFGGYYPDN--EVADHFWGSDTYLQDAHTWYIKMADRRP-----------------AW 377
            .:::.|.........:  |.|..|  |..::    |..:.:..|:|                 .|
Mouse   508 IDHKADLAVAPLTITHVREKAIDF--SKPFM----TLGVSILYRKPNGTNPSVFSFLNPLSPDIW 566

  Fly   378 QALVGIFEAYTWIGFILILI--ISWLFWFTLVMILPEPKYYQQLSLTAINALAVTISIAVQE--- 437
               :.:..||..:..:|.:|  .|...|:......|..:..:. :.|.:|:....:...:|:
Mouse   567 ---MYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVEN-NFTLLNSFWFGMGSLMQQGSE 627

  Fly   438 -RPICETTRLFFMALTLYGLNVVATYTSKMIA-----TFQDPGYLHQLDELTEVVAAGIPFGGHE 496
             .|...:||:.......:.|.::::||:.:.|     ..:.|  :...|:|.:  ...|.:|..:
Mouse   628 LMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESP--IDSADDLAK--QTKIEYGAVK 688

  Fly   497 E--SRDWFEND-----DDMWIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIY 554
            :  :..:|:..     :.||.|  .:..|..:.:: |.|.:   ||.:.::....|:|  ..:.|
Mouse   689 DGATMTFFKKSKISTFEKMWAF--MSSKPSALVKN-NEEGI---QRTLTADYALLMES--TTIEY 745

  Fly   555 AFPNNVFSSPV-QMIMKAGFPFLFEMNSIIRLMRDVGIFQKIDADFRYNNTYLNRINKMRPQF-- 616
            ....|...:.: .:|...|:.....|.|..|....:.|.|..:.|         :::.|:.::
Mouse   746 ITQRNCNLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEED---------KLHIMKEKWWR 801

  Fly   617 ----PE----TAIVLTTEHLKGPFFILVVGSCWAALTFIGELIIHRWRTQLVSTSEQQDRR---- 669
                ||    .|..|..:.:.|.|.:|..|...:.|..:||.|.     :|..|:|::.|.
Mouse   802 GSGCPEEENKEASALGIQKIGGIFIVLAAGLVLSVLVAVGEFIY-----KLRKTAEREQRSFCST 861

  Fly   670 -SDKRR-----RRRRRRKPE 683
             :|:.|     :||.:.||:
Mouse   862 VADEIRFSLTCQRRLKHKPQ 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Grik3	NP_001074566.1	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388	57/350 (16%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	72/411 (18%)
		Glutamate binding. /evidence=ECO:0000250	690..692		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846577
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830