Protein Alignment Ir60a and Gria4

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_006509904.1
• Gene: Gria4 / 14802
• MGIID: 95811
• Length: 912
• Species: Mus musculus
• Alignment Length: 708
• Identity: 124/708 - (17%)
• Similarity: 196/708 - (27%)
• Gaps: 346/708 - (48%)

  Fly    49 WKAGVGCLDSFAQI--FFFRNPKERFTRAYNLMLVH---------AFHLSSPADQIQEGFSKLIN 102
            |...:|...|..||  .|.||..:.:|.....:.:|         .|:|....|.|:...|..:.
Mouse    16 WGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVT 80

  Fly   103 EA-----------------------------------VTNPGPPDREELFQMRVASDYNITNGTE 132
            .|                                   :|...|.:.|..|.:::....
Mouse    81 NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFVLQLRPSL------- 138

  Fly   133 DKGELI-LADNY-----VIVVDSVDR----LKELMKKKIVEMRSWNPGARFLVLFHNATCRNRPL 187
             :|.|: |.|:|     |.:.|: ||    |:.:|:|  .....|:..|..:..|::.:.|
Mouse   139 -RGALLSLLDHYEWNCFVFLYDT-DRGYSILQAIMEK--AGQNGWHVSAICVENFNDVSYR---- 195

  Fly   188 GVASNIFKDL---MEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNVQ-------SVGQCH 242
                .:.::|   .|..:|                        ::|.|..:|       |||:..
Mouse   196 ----QLLEELDRRQEKKFV------------------------IDCEIERLQNILEQIVSVGKHV 232

  Fly   243 DGKLY--PNNAVVKASMQDYVSGFSPRNCTFFACSSISAPFV----------------------- 282
            .|..|  .|......|::.::.|.:  |.|.|.....:.|.|
Mouse   233 KGYHYIIANLGFKDISLERFIHGGA--NVTGFQLVDFNTPMVTKLMDRWKKLDQREYPGSETPPK 295

  Fly   283 --------------------------------EADCIL--------GLEM-------RILGFMKN 300
                                            ..||:.        |::|       ||.|...|
Mouse   296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360

  Fly   301 RLKFD-----VNQTC---SLESRGE---------------MDGPANWTGLLGK----VQNN---- 334
             ::||     ||.|.   .|:|.|.               .|.|.     ||.    ::|.
Mouse   361 -VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDAPT-----LGNDTAAIENRTVVV 419

  Fly   335 ----ECDFV--------------FGGYYPD--NEVADHF-------------WGSDTYLQDAHTW 366
                |..:|              :.||..|  :|:|.|.             :|:    :||.|
Mouse   420 TTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA----RDADT- 479

  Fly   367 YIKMADRRPAWQALVGIFEAYTWIGFILILIISWLFWFTLVMILPEPKYYQQLSLTAINALAVTI 431
                    ..|..:||                ..::....:.|.|       |::|.:....:..
Mouse   480 --------KIWNGMVG----------------ELVYGKAEIAIAP-------LTITLVREEVIDF 513

  Fly   432 SIAVQERPICETTRLFFMALTLYGLNVVATYTSKMIATFQDPGYLHQLDELTE-----VVAAGI- 490
            |     :|        ||:|   |::::.....|     ..||....||.|..     :|.|.|
Mouse   514 S-----KP--------FMSL---GISIMIKKPQK-----SKPGVFSFLDPLAYEIWMCIVFAYIG 557

  Fly   491 ------------PFGGH-EESRDWFENDDD-----MWIFN------------GYNISP 518
                        |:..| ||..|..|...|     ..|||            |.:|||
Mouse   558 VSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Gria4	XP_006509904.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	68/417 (16%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	49/259 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846575
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830