Protein Alignment Ir60a and GRIN3B

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_619635.1
• Gene: GRIN3B / 116444
• HGNCID: 16768
• Length: 1043
• Species: Homo sapiens
• Alignment Length: 559
• Identity: 106/559 - (18%)
• Similarity: 186/559 - (33%)
• Gaps: 150/559 - (26%)

  Fly   239 GQCHDGKL-----YPNNAVVKASMQDYVSGFSP---RNCTFFACSSISAPFVEADCILGLEMRIL 295
            |||..|:|     ..::|.:.|......:|.:|   |.|.:..|..:.....| |.....|:.::
Human   437 GQCPAGQLCLDPGTNDSATLDALFAALANGSAPRALRKCCYGYCIDLLERLAE-DTPFDFELYLV 500

  Fly   296 GFMKNRLKFDVNQTCSLESRGEM-DGPANWTGLLGKVQNNECDFVFGGYYPD---NEVADHFWGS 356
            |..|               .|.: ||  .||||:|.:...........:..:   ::|.|.   :
Human   501 GDGK---------------YGALRDG--RWTGLVGDLLAGRAHMAVTSFSINSARSQVVDF---T 545

  Fly   357 DTYLQDAHTWYIKMADRRPAWQALVGIFEAYTWIGFILILIISWLF-----WFTLVMILPEPK-- 414
            ..:...:....::..|......|.:......||:|....|.::.||     |.:...:.|..:
Human   546 SPFFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSPYGLTPRGRNR 610

  Fly   415 -----YYQQLSLTAINALAVTISIAVQERPICETTRLFFMALTLYGLNVVATYTSKMIA------ 468
                 |...|:|........|:|   .:.|.|.|.||......::.|.|:::||:.:.|
Human   611 STVFSYSSALNLCYAILFRRTVS---SKTPKCPTGRLLMNLWAIFCLLVLSSYTANLAAVMVGDK 672

  Fly   469 TFQDPGYLHQLDELTEVVAAGIPFGGHEESRDWFENDDDMWIFNGYNISPEFIPQSKNLEA--VK 531
            ||::...:|  |......|.|..||     ..| |:..:.:|...:   |:.....:...|  ..
Human   673 TFEELSGIH--DPKLHHPAQGFRFG-----TVW-ESSAEAYIKKSF---PDMHAHMRRHSAPTTP 726

  Fly   532 WGQRCILSN----RMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFE-------------- 578
            .|...:.|:    ..:.|...|.|...:...:.      .::..|.||..|
Human   727 RGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADC------KLLTVGKPFAIEGYGIGLPQNSPLTS 785

  Fly   579 -MNSIIRLMRDVGIFQKIDADFRYNNTYLNRINKMRP----QFPET-AIVLTTEHLKGPFFILVV 637
             ::..|...:..|..     |..::..|     ||.|    .|..| .:.::..|..|.|.:|.:
Human   786 NLSEFISRYKSSGFI-----DLLHDKWY-----KMVPCGKRVFAVTETLQMSIYHFAGLFVLLCL 840

  Fly   638 GSCWAALTFIGE-----LIIHRWR--------------------------------------TQL 659
            |...|.|:.:||     |.:.|.|                                      .::
Human   841 GLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQKIHRALNTEPPEGSKEETAEAEPSGPEV 905

  Fly   660 VSTSEQQDRRSDKRRRRRRRRKPEKDNRWQRQVQVAPVV 698
            ....:|||:.:.....:|.||..:|:.|.:..::.|.||
Human   906 EQQQQQQDQPTAPEGWKRARRAVDKERRVRFLLEPAVVV 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
GRIN3B	NP_619635.1	PBP1_iGluR_NMDA_NR3	19..405	CDD:107372
		PBP2_iGluR_NMDA_Nr3	415..808	CDD:270438	77/416 (19%)
		Lig_chan	576..842	CDD:278489	58/295 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156154
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.830