Protein Alignment Ir60a and Grik4

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_780690.2
• Gene: Grik4 / 110637
• MGIID: 95817
• Length: 956
• Species: Mus musculus
• Alignment Length: 626
• Identity: 134/626 - (21%)
• Similarity: 217/626 - (34%)
• Gaps: 162/626 - (25%)

  Fly   210 YANSTMNYNLLV-------------NDYYSNVNCRIL-----NVQSVGQCH-------DGKLYPN 249
            :..|.|||..:|             ....||...:||     ..|.:||.|       |.:||.:
Mouse   343 HGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFQQIGQWHVAEGLSMDSRLYAS 407

  Fly   250 NAVVKASMQDYVSGFSPRNCTFFACSSISAPFVEADCILG--LEM----RILGFMKNRLK----- 303
            |      :.|     |..|.|....:.:..|::   .:.|  .||    |..||..:.||
Mouse   408 N------ISD-----SLFNTTLVVTTILENPYL---MLKGNHQEMEGNDRYEGFCVDMLKELAEI 458

  Fly   304 FDVNQTCSLESRGEMDGP-AN--WTGLLGKVQNNECDFVFGG--YYPDNEVADHFWGSDTYLQDA 363
            ...|....|...|....| ||  |||::|::...:.|....|  ...:.|....|......|..:
Mouse   459 LRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGIS 523

  Fly   364 HTWYIKMADRRPAWQALVGIFEAYTWIGFILILIISWLFWFTLVMILPEPKY------------- 415
            ..:.:.|. |||.:.:.:..|....|:..:|..:......|.:..:.|...|
Mouse   524 ILYRVHMG-RRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLL 587

  Fly   416 YQQLSLTAINALAVTISIAVQE----RPICETTRLFFMALTLYGLNVVATYTSKMIA-----TFQ 471
            ..|.||.  |:|...:...:|:    .|...:||........:.|.::::||:.:.|     ..:
Mouse   588 VNQYSLG--NSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRME 650

  Fly   472 DPGYLHQLDELTEVVAA--GIPFGGHEESRDWFEND-----DDMWIFNGYNISPEFIPQSKNLEA 529
            .|  :..:|:|.:..|.  |...||  .|..:|:|.     ..||.:. |:..|....:|.. |.
Mouse   651 VP--IESVDDLADQTAIEYGTIHGG--SSMTFFQNSRYQTYQRMWNYM-YSKQPSVFVKSTE-EG 709

  Fly   530 VKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFEMNSIIRLMRDVGIFQK 594
            :   .|.:.||..:.::|.:.: .|...|...:....::...|:.....:.|:.|...|:.|.|
Mouse   710 I---ARVLNSNYAFLLESTMNE-YYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQ- 769

  Fly   595 IDADFRYNNTYLNRINKMRPQFPE----------TAIVLTTEHLKGPFFILVVGSC----WAALT 645
                .:.|    ||:..::.::.|          .|..|..|::.|.|.:|:.|..    .|.|.
Mouse   770 ----LQEN----NRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLE 826

  Fly   646 FIGEL---------IIHRWRTQLVSTSEQQDRRSDKRRRR---------RRRRKP---------- 682
            |:..|         :.....|:|.:....||....:|||.         ...|:|
Mouse   827 FLWTLRHSEASEVSVCQEMVTELRNIILCQDNIHPRRRRSGGLPPQPPVLEERRPRGTATLSNGK 891

  Fly   683 -----EKDNRWQRQVQVAPVV-------RFTPVKRRKVFQG 711
                 |.|...||..|.|.:|       |..|..||  |||
Mouse   892 LCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRR--FQG 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
Grik4	NP_780690.2	Periplasmic_Binding_Protein_type1	24..402	CDD:385651	13/58 (22%)
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	80/394 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956		134/626 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846211
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830