Protein Alignment Ir60a and grik5

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 582
• Identity: 110/582 - (18%)
• Similarity: 199/582 - (34%)
• Gaps: 164/582 - (28%)

  Fly   210 YANSTMNYNLLVNDY--------------YSNVNCRILNVQSVGQCHDGKLYPNNAV-VKASMQD 259
            :..|.|||..:| :|              .:|...|||.....|....|..|.|..: :.|:..|
 Frog   346 HGTSLMNYLRMV-EYDGLTGRVEFNSKGQRTNYTLRILEKAGDGHREIGVWYSNRTLAMNATSLD 409

  Fly   260 YVSGFSPRNCTFFACSSISAPFV---------------EADCI-LGLEMRILGFMKNRLKFDVNQ 308
            ..:..:..|.|....:.:..|::               |..|. :.:|:..|      |:|  |.
 Frog   410 LSTSETLENKTLVVTTILENPYMMRKSNYRSLSGNDQYEGFCAEMLMELAAL------LRF--NY 466

  Fly   309 TCSLESRGEMDGP---ANWTGLLGKVQNNECDFVFGGY--YPDNEVADHFWGSDTYLQDAHTWYI 368
            ...|...|....|   .:|||::|::.|.:.|.....:  ..:.|....|......|..:..:.:
 Frog   467 KIKLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRV 531

  Fly   369 KMADRRPAWQALVGIFEAYTWIGFILI--LIISWLF----------WFTLVMILPEPKYYQQLSL 421
            :|. |:|.:.:.:..|....|: |:|:  |.:|.:.          |:.....|.|..:..:...
 Frog   532 QMG-RKPGYFSFLDPFSPAVWL-FMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRERHHILENQY 594

  Fly   422 TAINALAVTISIAVQE----RPICETTRLFFMALTLYGLNVVATYTSKMIA-----TFQDPGYLH 477
            |..|:|...:...:|:    .|...:||........:.|.::::||:.:.|     ..:.|  :.
 Frog   595 TLGNSLWFPVGGFMQQGSEVMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVP--IE 657

  Fly   478 QLDELTEV--VAAGIPFGGHEESRDWFEND-----DDMWIFNGYNISPEFIPQSKNLEAVKWGQR 535
            ..|:|.:.  :..|...||  .:..:|:|.     ..||.:........|:..::.      |..
 Frog   658 SADDLADQTNIEYGTIHGG--STMTFFQNSRYQTYQRMWNYMNSKQPSVFVKSTEE------GIA 714

  Fly   536 CILSNRMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGFPFLFE--MNSIIRLM------------ 586
            .:|::|                               :.||.|  ||...|.:
 Frog   715 RVLNSR-------------------------------YAFLLESTMNEYHRRLNCNLTQIGGLLD 748

  Fly   587 -RDVGIFQKIDADFRYNNTYL-------NRINKMRPQFPE----------TAIVLTTEHLKGPFF 633
             :..||...:.:.:|...|..       ||:..::.::.|          .|..|..|::.|.|.
 Frog   749 TKGYGIGMPLGSPYRDEITLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFV 813

  Fly   634 ILVVGSCWAALTFIGELIIHRWRTQLVSTSEQ----QDRRSDKR---------RRRRRRRKP 682
            :|:.|...|....|.|.:   |.|:....:|:    |:..|:.|         |.|.|||.|
 Frog   814 VLICGLIIAVFVAIMEFV---WSTRRSVDNEEISVCQEMLSELRSAVSCKKTSRSRHRRRPP 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	14/59 (24%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:473866	71/420 (17%)