Protein Alignment Ir60a and grin2c

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: XP_012808364.2
• Gene: grin2c / 100496638
• XenbaseID: XB-GENE-993386
• Length: 1189
• Species: Xenopus tropicalis
• Alignment Length: 763
• Identity: 133/763 - (17%)
• Similarity: 257/763 - (33%)
• Gaps: 204/763 - (26%)

  Fly    28 SNETANTVIF-MLPEKDLGPDVWKAGVGCLDSFAQIFFFRNPKERFTRAYNLMLVHAFHLSSP-- 89
            |.|...|||. :|.|.||||            |:.|          |..|.   .|...||:.
 Frog   144 SLEQQLTVILKVLEEYDLGP------------FSVI----------TSHYP---GHRLFLSAVRA 183

  Fly    90 -ADQIQEGFSKLINEAVTNPGPP--------------------DREELFQMRVASDY-------- 125
             .:.:|.|:... :|....||..                    .|:|..:|.:|:..
 Frog   184 LCEALQPGWGPQ-DELTVEPGAGPKGTQRVLRQVSAPVLLLFCSRDEAEEMFIAAGEAGLLGPSH 247

  Fly   126 -----NITNGTEDKGELILADNYVIVVDSVDRLKELMKKKIVE-MRSWNPGARFLVLFH------ 178
                 :.|.|:.|:.........|.||  .|..:..:::|:.: :.....||:..:..|
 Frog   248 IWVVPSFTIGSPDRPAPFFPVGLVSVV--TDGWRRSLRQKVQDGIAVIAAGAKNYLQRHGELPQP 310

  Fly   179 NATCRNRP-LGVASNIFKDLMEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNV------Q 236
            ..:|...| |.....:::.:|...:.||        .:::|  ...|..:.:..::.:      :
 Frog   311 RGSCLAPPHLHGNDTLYRHMMNTVWKHR--------EVSFN--SQGYLLDPSMLVITLTPHRAWE 365

  Fly   237 SVGQCHDGKL---YP-------NNAVVKASMQ-----------------DYVSGFSPRN---C-- 269
            .||:...|.:   ||       .|.:|..|..                 |..:|...||   |
 Frog   366 EVGRWESGIIRMKYPVWPRYGAGNQLVTDSRHLTVATLEERPFVIVESTDPATGDCIRNTVPCRK 430

  Fly   270 -TFFACSSISAPFVEADCILGLEMRILGFMKNRLKFDVNQTCSLESRGEMDGPAN--WTGLLGKV 331
             :....||...|:.:. |..|..:.||..:...:||..:  ..|.:.|:......  |.|::|:|
 Frog   431 QSNLTLSSSGEPYTKL-CCKGFCIDILKKLARTVKFSYD--LYLVTNGKHGKLVRGVWNGMIGEV 492

  Fly   332 QNNECDFVFGGYYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQALVGIFEAYTW-IGFILI 395
            .........|....:.|.::....|..:::...:..:..::...:..|.:..:....| :.|::.
 Frog   493 YYRRAHLAIGSLTINEERSEIVDFSVPFVETGISVLVSRSNGTVSPSAFLEPYSPAVWMMMFVMC 557

  Fly   396 LIISWLFWFTLVMILP--------------EPKYYQQLSLTAINALAVTISIAVQERPICETTRL 446
            |.:..:..|......|              .|.:....||..:.||....|:.:| .|...|:::
 Frog   558 LSVVAVTVFIFEYFSPMGYDQDLSNGKRLGGPSFTIGKSLWLLWALVFNNSVPIQ-NPRGTTSKI 621

  Fly   447 FFMALTLYGLNVVATYTSKMIATFQDPGYLHQLDELTE------------VVAAGIPFGGHEESR 499
            ..:....:.:..:|:||:.:.|......|:..:..|::            .....:|.|..|  |
 Frog   622 MVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDRKFQKPQEQYPPFRFGTVPNGSTE--R 684

  Fly   500 DWFENDDDMWIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSP 564
            :...|..||..:                 .|::.||.:..    .:.|..|..:.||   ::.:.
 Frog   685 NIRTNYPDMHSY-----------------MVRYNQRSVED----ALASLKAGKLDAF---IYDAA 725

  Fly   565 V-------------------QMIMKAGFPFLFEMNSIIRLMRDVGIFQKI-DADF-RYNNTYLNR 608
            |                   ::....|:....:.||..:...|:.:.|.: |.|. |....:|:.
 Frog   726 VLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKNSRWKRPIDLALLQFLGDGDTQRLETVWLSG 790

  Fly   609 INKMRPQFPETAIVLTTEHLKGPFFILVVGSCWAALTFIGELIIHRWR 656
            |.: ..:....:..|..:::.|.|::|:|....:.|.|..|.::: ||
 Frog   791 ICQ-NEKNEAVSSKLDIDNMAGVFYMLLVAMGLSLLVFSWEHLVY-WR 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grin2c	XP_012808364.2	Periplasmic_Binding_Protein_type1	30..379	CDD:471960	49/272 (18%)
		PBP2_iGluR_NMDA_Nr2	395..794	CDD:270436	70/429 (16%)
		NMDAR2_C	831..>906	CDD:463148	2/7 (29%)