DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir60a and grid2

DIOPT Version :9

Sequence 1:	NP_611901.1	Gene:	Ir60a / 37881	FlyBaseID:	FBgn0034994	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	XP_031759030.1	Gene:	grid2 / 100487676	XenbaseID:	XB-GENE-955038	Length:	1007	Species:	Xenopus tropicalis

Alignment Length:	511	Identity:	100/511 - (19%)
Similarity:	181/511 - (35%)	Gaps:	137/511 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 NNAVVKASMQDYVSGFSPRNCTFFACSSISAPFV-EADCILGLEMRILGFMKNRL---------K 303
            |.::....:::.:.|...|..|.     :..||| .::.:||...:..||..:.|         |
Frog   426 NGSLTDRKLENNMRGVVLRVATV-----LEEPFVMVSENVLGKPKKYQGFSIDVLDALSSYLGFK 485

  Fly   304 FDVNQTCSLESRGEMDGPANWTGLLGKVQNNECDFVFGG--YYPDNEVADHFWGSDTYLQDAHTW 366
            ::: ...|....|......:|.||:|::.....|.....  ..||.|....|  :..|:..:...
Frog   486 YEI-YVASDHKYGSPQADGSWNGLIGELLLKRADMGISALTITPDRENVVDF--TTRYMDYSVGV 547

  Fly   367 YIKMADRRPAWQALVGIFEAYTW---------IGFILILIISWLFWFTLVMILPEPKYYQQLSLT 422
            .::.|::.....|.:..|:...|         :| :|:.:::||          .|...|..|:|
Frog   548 LLRKAEKTVDMFACLAPFDLSLWACIAGTVLLVG-LLVYLLNWL----------NPPRLQMGSMT 601

  Fly   423 A---INALAVTISIAVQ---ERPICE-TTRLFFMALTLYGLNVVATYTSKMIATF---QDPGYLH 477
            :   .|::.......||   |.|... .||:...|..|:.|.|:::||:.:.|..   :....:.
Frog   602 STTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTISRIESSIQ 666

  Fly   478 QLDELTEVVAAGIPFGGHEESRDW----------FEND---DDMW-IFNGYNISPEFIPQS-KNL 527
            .|.:|:.  ...||:|...:|..:          ||.|   ..|| :.|..|.|...:.:| :.:
Frog   667 SLQDLSR--QTDIPYGTVFDSAVYEHVRVKGMNPFERDSMYSQMWRMINRSNGSENNVQESLEGI 729

  Fly   528 EAVKWG------------------QRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGFP 574
            :.||.|                  |.|    ..||:.:.:||..|.           :.::.|.|
Frog   730 QKVKHGNYAFVWDAAVLEYIAINDQDC----SFYTVGNTIADRGYG-----------IALQHGSP 779

  Fly   575 FLFEMNSIIRLMRDVGIFQKIDADFRYNNTYLNRINKMRPQFPETAI-----------VLTTEHL 628
            :           ||  ||.:...:.:.|.......:|..|:..:..:           .|..:..
Frog   780 Y-----------RD--IFSQRILELQQNGDMDILKHKWWPRNGQCELHSSMDTKQKGSSLDIKSF 831

  Fly   629 KGPFFILVVG---SCWAALTFIGELIIHRWRTQLVST---SEQQDRRSDKRRRRRR 678
            .|.|.||..|   ||:.|:       :..|..:...:   |::.|:..|.....||
Frog   832 SGVFCILAAGIVLSCFIAM-------VETWWNKKKGSRVPSKEDDKEIDLEHLHRR 880

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:415822	1/2 (50%)
grid2	XP_031759030.1	PBP2_iGluR_delta_2	440..806	CDD:270449	83/414 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910