Protein Alignment Ir60a and grid1

DIOPT Version :10

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 780
• Identity: 149/780 - (19%)
• Similarity: 254/780 - (32%)
• Gaps: 220/780 - (28%)

  Fly    58 SFAQIF--FFRNPKERFTRAYNLMLVHAFHLSSPADQIQEGFSKLINEAVTNPGPPDREELFQMR 120
            :.:::|  .|.:.|......|...|..|..|.||     .|....|:|||.
 Frog   200 NISRVFATLFTSMKTEELNRYRDTLRRAILLLSP-----RGAQSFISEAVE-------------- 245

  Fly   121 VASDYNITNGTEDKGELILADNYVIVVDSVDRLKELMKKKIVEMRSWNPGARFLVLFHNATCRNR 185
                   ||       |...|::.:.|:     :|:...:|||            |.|:|..|
 Frog   246 -------TN-------LASKDSHWVYVN-----EEINDAEIVE------------LVHSALGR-- 277

  Fly   186 PLGVASNIFKDLME-----MFYVHRVALLYANSTMNY-------NL--------LVNDYY----- 225
             :.|...||..|.:     :...||:|.|..:....|       ||        |.|.::
 Frog   278 -ITVIRQIFPSLKDNNIRCVRNNHRIASLPCDPQEGYLQMLQVSNLYLYDSVLMLANAFHRKLED 341

  Fly   226 ------SNVNC---------------------RILNVQSVGQCHDGKLYPN-------------- 249
                  :::||                     ||..:..:.:..:....|:
 Frog   342 RKWHSMASLNCMRKSTKPWNGGRSMLDTIKKGRITGLTGIMEFKEAGANPHVQFEILGTSYSETF 406

  Fly   250 -NAVVKASMQDYVSGFS------PRN-----CTFFACSSISAPFV-EADCILGLEMRILGF---- 297
             ..|.:.:..|.:.||:      |.|     .|....:.:..||| .|:.|||...|..||
 Frog   407 GKDVRRLATWDSMKGFNGSLQEKPLNNDLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIEI 471

  Fly   298 ---MKNRL--KFDVNQTCSLESRGEMDGPANWTGLLGKVQNNECDFVFGG--YYPDNEVADHFWG 355
               :.|||  |:::.|... ...|......:|.|::|::.|...|.....  ..|:.|....|
 Frog   472 LDELSNRLGFKYEIYQAPD-GKYGHQLSNGSWNGMIGELINKRADIAISAITITPERENVVDF-- 533

  Fly   356 SDTYLQDAHTWYIKMADRRPAWQALVGIFEAYTWIGFILILIISWLFWFTL-----VMILPEPKY 415
            :..||..:....||..:.|....:|...|:...|.....::.:..:..|.|     |......:.
 Frog   534 TKRYLDYSVGILIKKPEERINIFSLFAPFDFAVWACIAAVIPVVGVLIFVLNRIQAVRAQNSSQT 598

  Fly   416 YQQLSLTAINALAVTISIAVQE----RPICETTRLFFMALTLYGLNVVATYTSKM---------- 466
            .|..|.|..:|:.:.....||:    .......|:...:..|:.|.|.::||:.:
 Frog   599 SQSTSSTLHSAIWIVYGAFVQQGGESAANSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMD 663

  Fly   467 --IATFQDPGYLHQLDELTEVVAAGIPFGGHEESR--DWFENDD-----------DMWIFNGYN- 515
              |.||||  ...|:|         :|:|..::|.  ::|::..           ::|...|.|
 Frog   664 NPIRTFQD--LAKQVD---------LPYGTVKDSSVYEYFKSKGTNTLVQDRTFAELWRTIGKNN 717

  Fly   516 ------ISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLAD---VIYAFPNNVFSSPVQMIMKA 571
                  .||     |:.:...|.|....|.:......:.|.|   .:....|.:.|....:.::.
 Frog   718 GSDNCVSSP-----SEGIRKAKRGNYAFLWDVTVVEYAALTDDECSVAVTGNTISSKGYGIALQH 777

  Fly   572 GFPFLFEMNSIIRLMRDVGIFQKIDADF--RYNNTYLNRINKMRPQFPETAIVLTTEHLKGPFFI 634
            |.|:....:..|...:|.|....:...:  |.....||..|..:    .....|......|.|.|
 Frog   778 GSPYRDIFSQRILEFQDSGRLDVLKEKWWPRTGRCDLNSHNNAQ----NDGKALKLHSFAGVFCI 838

  Fly   635 LVVGSCWAALTFIGELIIHRW--RTQLVSTSEQQDRRSDKRRRRRRRRKPEKDNRWQRQVQVAPV 697
            |.:|...|.|....||    |  ..:....|.::|:..:..:..||......::...:|:..|.:
 Frog   839 LAIGLLLACLVAALEL----WWNSNRCRQDSPKEDKEVNLEQVHRRLNSLIDEDMAHKQISTASI 899

  Fly   698  697
             Frog   900  899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..426	CDD:380615	49/278 (18%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	77/388 (20%)