Protein Alignment Ir60a and grin2ca

DIOPT Version :9

• Sequence 1: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001352716.1
• Gene: grin2ca / 100003342
• ZFINID: ZDB-GENE-070822-3
• Length: 1400
• Species: Danio rerio
• Alignment Length: 703
• Identity: 119/703 - (16%)
• Similarity: 241/703 - (34%)
• Gaps: 184/703 - (26%)

  Fly    78 LMLVHAFHLSSPADQIQEGFSKLINEAVTNPG----------------PPDREELFQMRVASD-- 124
            ::||:..|     |:.|..||......:..||                |||...:..:.:.:|
Zfish   233 VLLVYCSH-----DEAQYLFSMAREVGLVGPGYIWFIPSLAVGNPNIAPPDSFPVGLISIITDRW 292

  Fly   125 -YNITNGTEDKGELILADNYVIVVDSVDRLKELMKKKIVEMRSWNPGARFLVLFHNATCRNRPLG 188
             .::.|.        :.|...|||..|:..:        :.|.:.|......|        .|:.
Zfish   293 KMSLRNR--------VRDGVAIVVKGVESFR--------KQRGFIPDGHMDCL--------SPIR 333

  Fly   189 VASNIFKDLMEMFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNV------QSVGQCHDGKL- 246
            .|||      ...|.|.:.:.:.|:..::|  .:.|..|.:..|:.:      ..||....|.|
Zfish   334 PASN------GTLYRHMLNVSWENTDFSFN--SDGYLVNPSMIIITLDRGRQWDKVGNYESGILQ 390

  Fly   247 --YP--------------NNAVVKASMQD----YVSGFSPRNCTFFACSSISAPFVEAD------ 285
              ||              |..:..|::::    .|....|...|   |.|.:.|.....
Zfish   391 MRYPVWPRYGTFLEPVSDNRHLTVATLEERPFVIVEAVDPVTGT---CLSNTVPCRRQSNKTETI 452

  Fly   286 ----------CILGLEMRILGFMKNRLKFDVNQTCSLESRGEMDGPAN--WTGLLGKVQNNECDF 338
                      |..|..:.||..:...:||..:  ..|.:.|:......  |.|::|:|.....|.
Zfish   453 VGHTEPYTKLCCKGFCIDILKKLSRNIKFSYD--LYLVTNGKHGKLVRGIWNGMIGEVFYKRADM 515

  Fly   339 VFGGYYPDNEVADHFWGSDTYLQDAHTWYIKMADRRPAWQALVGIFEAYTWI-GFILILIISWLF 402
            ..|....:.|.::....|..:::...:..:..::...:..|.:..:....|: .|::.|.:..:.
Zfish   516 AIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVT 580

  Fly   403 WFTLVMILPEPKYYQQLSLTAINALAVTISIAVQ---------------ERPICETTRLFFMALT 452
            .|  |.....|..|.:..::|.:....|.:|...               |.|...|:::..:...
Zfish   581 VF--VFEYCSPVGYNRSLVSAKDPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWA 643

  Fly   453 LYGLNVVATYTSKMIATFQDPGYLHQLDELTEVVAAGIPFGGHEESRDWFENDDDMW-------I 510
            .:.:..:|:||:.:.|......|:..:..|::               ..|:...|.:       :
Zfish   644 FFAVIFLASYTANLAAFMIQEQYIDTVSGLSD---------------KKFQKPQDQYPPFRFGTV 693

  Fly   511 FNG---YNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPV------- 565
            .||   .||...:.....::  ||:.|:.: .:.:.::::...|   ||   ::.:.|
Zfish   694 PNGSTERNIRSNYPEMHSHM--VKYNQKGV-EDALNSLKTGKLD---AF---IYDAAVLNYMAGK 749

  Fly   566 ------------QMIMKAGFPFLFEMNSIIRLMRDVGIFQKI-DADF-RYNNTYLNRINKMRPQF 616
                        ::....|:....:..|..:...|:.:.|.: |.|. :....:|..|  .|.:.
Zfish   750 DEGCKLVTIGSGKVFATTGYGIALQKESRWKRPIDLALLQFLADGDTQKLQTVWLTGI--CRNEK 812

  Fly   617 PET-AIVLTTEHLKGPFFILVVGSCWAALTFIGELIIHRWRTQ-LVSTSEQQD 667
            .|. :..|..:::.|.|::|:|....:.|.|..|.::: |:.: .|..||:.|
Zfish   813 KEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLY-WKLRHSVRKSERLD 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60a	NP_611901.1	None
grin2ca	NP_001352716.1	PBP1_iGluR_NMDA_NR2	38..398	CDD:107373	39/201 (19%)
		PBP2_iGluR_NMDA_Nr2	409..810	CDD:270436	65/433 (15%)
		NMDAR2_C	847..>938	CDD:313729	5/19 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591634
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830