Protein Alignment KCNS2 and Kcns2

DIOPT Version :10

• Sequence 1: NP_065748.1
• Gene: KCNS2 / 3788
• HGNCID: 6301
• Length: 477
• Species: Homo sapiens
• Sequence 2: NP_076456.1
• Gene: Kcns2 / 66022
• RGDID: 621525
• Length: 477
• Species: Rattus norvegicus
• Alignment Length: 476
• Identity: 468/476 - (98%)
• Similarity: 474/476 - (99%)
• Gaps: 0/476 - (0%)

Human     1 MTGQSLWDVSEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDV 65
            ||.|||||:||.:||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MTRQSLWDLSETDVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDV 65

Human    66 QREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEP 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 QREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEP 130

Human   131 EQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSILSIL 195
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
  Rat   131 EQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQLWLALDNPGYSVLSRVFSVLSIL 195

Human   196 VVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNAL 260
            ||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 VVLGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNAL 260

Human   261 NLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYS 325
            |||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||
  Rat   261 NLIDLMSIVPFYITLVVNLVVESSPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYS 325

Human   326 YKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLT 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 YKEVGLLLLYLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLT 390

Human   391 ASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSL 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 ASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAHKVKSL 455

Human   456 MASLTNMSRSSPSELSLNDSL 476
            |||||||||||||||||:|||
  Rat   456 MASLTNMSRSSPSELSLDDSL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNS2	NP_065748.1	BTB_POZ_KCNS2	18..124	CDD:349734	105/105 (100%)
		Ion_trans	186..421	CDD:459842	231/234 (99%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	374..379		4/4 (100%)
Kcns2	NP_076456.1	BTB_POZ_KCNS2	18..124	CDD:349734	105/105 (100%)
		Ion_trans	186..421	CDD:459842	231/234 (99%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	374..379		4/4 (100%)