DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11406 and mag

DIOPT Version :9

Sequence 1:	NP_001014548.1	Gene:	CG11406 / 37877	FlyBaseID:	FBgn0034990	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_649229.1	Gene:	mag / 40267	FlyBaseID:	FBgn0036996	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	375	Identity:	134/375 - (35%)
Similarity:	193/375 - (51%)	Gaps:	51/375 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 QVHRIETADGYRLSLHRIP-----APQNRWCPQQLRPFLLMHGLLGSAGDFVSGGRGRSLALELH 95
            :.|.:.|.|||.|:|.|||     ..||...|    |.||.|||..::..::|.|...|||..|.
  Fly    44 ETHEVTTQDGYVLTLFRIPYSHKLKNQNEKRP----PILLQHGLFSNSDCWLSSGPDNSLAYLLA 104

  Fly    96 ARCFDVWLANARGTTHSRGHRTLQTSDARFWRFSWHEIGIYDLPAIVDYVLARTNRRQLHYVGHS 160
            ...:||||.||||..:||.:..:..:..:||.|.|||||..|:||::||:||.|...|:||.|||
  Fly   105 DAGYDVWLGNARGNIYSRNNIIISLNSHKFWHFDWHEIGTIDIPAMIDYILADTGFDQIHYAGHS 169

  Fly   161 QGTTVLLVLLSQRPEYNARFANAALLAPVAFLQHLSSPPLRLLASDSSMATLLLNKLGL------ 219
            |||||.||:||:||||||...:..||||.||.:|.:|              .:.|.||.
  Fly   170 QGTTVYLVMLSERPEYNALIKSGHLLAPCAFFEHGTS--------------FIFNALGPLVGTPG 220

  Fly   220 ---------HELLPASALTQVGGQFFCTASRPTYALCTLFTSVYVGFSD---YPLDRSILPRILE 272
                     .||:|.:.|........|..|.      |:..:.::.|::   ...:.|.:..::|
  Fly   221 GIWNQLLVDTELIPNNNLVNRLVDNSCHLSN------TICNNAFIMFANGGYVNANASSMSVLIE 279

  Fly   273 TTPAGISRGQLQHFGQLINSGKFQQYDYRSPRLNTLRYGRTTPPSYQLANVRLQLQIFHGSRDTL 337
            |.|||.|..|..|:.||..|.||:|||:.:.:.|.| ||:..||.|.|:.:.....::..:.|.|
  Fly   280 THPAGSSSNQGIHYLQLWKSLKFRQYDWGTKKNNEL-YGQDLPPDYDLSKIVAPTHLYSSTNDAL 343

  Fly   338 SSLADVQRLVRELRNSVTQMYQVP--GYNHIDFLFASSAPQVVFQRIIQQ 385
            ....||..||....: :|:.|:||  .:||:||:.|.:..::|...||::
  Fly   344 CGPEDVNTLVENFPH-LTEDYRVPVQSFNHLDFIIAKNMKELVNDPIIER 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11406	NP_001014548.1	Abhydro_lipase	28..85	CDD:282003	20/53 (38%)
		Abhydrolase_1	67..371	CDD:278959	117/323 (36%)
		Abhydrolase_5	67..>203	CDD:289465	67/135 (50%)
		Abhydrolase_5	<315..365	CDD:289465	14/51 (27%)
mag	NP_649229.1	Abhydro_lipase	34..94	CDD:282003	20/53 (38%)
		MhpC	56..366	CDD:223669	119/335 (36%)
		Abhydrolase_5	76..>197	CDD:289465	61/120 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439412
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900