Protein Alignment CG3356 and herc5.2

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: XP_005160175.1
• Gene: herc5.2 / 794323
• ZFINID: ZDB-GENE-090311-16
• Length: 987
• Species: Danio rerio
• Alignment Length: 595
• Identity: 149/595 - (25%)
• Similarity: 243/595 - (40%)
• Gaps: 107/595 - (17%)

  Fly   548 MLFGRLLPTLHDVEFVE-NKLL----LQVHSTINHVRLMPFSIAEIIQM--SKTLKDISMGLVEL 605
            :|...|:..|...:..| ||.|    ||::|          :..|:::|  ||...|....||:|
Zfish   462 LLLPELIKGLEQYQRSELNKALASKILQLNS----------AAREMLEMFWSKLPDDWLKSLVKL 516

  Fly   606 AFPETRSNLANYRKVLGHTEADDKKLRHQKQIWANLLNVVVFVLNQIHTRDLRLGF--CPEDHWT 668
             |.:..::|.:|..|.    |.|..|:|.:    |||.:            |::.:  |...|..
Zfish   517 -FHKESADLIDYMSVC----AMDSDLKHLQ----NLLRI------------LQMAYKVCCSTHRD 560

  Fly   669 VTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFT-----REDFENGPPMSTKQIRSITILREIP 728
            :|..|..:...:||.....:.:..:..:.|..|:.     |:.|          |:::.||.:.|
Zfish   561 ITISDFIIYEISDLLNALQATIDDLADWDPFVDYVYMMKLRDYF----------IKTLEILVKFP 615

  Fly   729 FVVPFNKRVSILQSL----VAASKMRVQGNMQAFLQGPSVLITVRRSHLYEDAYDKLRPDNEPDL 789
            ||..:..:..|...|    :..|..|..||      ....::.:.|..|..|....|| .|....
Zfish   616 FVADYASKRGIFNHLEIKMIRRSSNRFLGN------ATFNVLHINRESLLMDTLKYLR-QNTHSF 673

  Fly   790 RFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDNKLYPNPNVADLFEDY 854
            ....|:.|:.     |.|||..|:..||.|.:.|:....::....|...:.::.||:    ....
Zfish   674 SHLSRVAFIG-----EDGIDMRGLSAEFFSLISKSFLKWDKKILEVHPSSLVWFNPH----HTRG 729

  Fly   855 EKHYYFIGRILGKSIY--ENLLVELPLAEFFLTKLAGKYSDVDIHQLASLDPELYRNLLYLKDYS 917
            .|::|::|.|.|.::|  .::.::.||| .|...|..|.|..|:.:|:.::....:||  ||:..
Zfish   730 NKNFYYLGVICGMALYNRHHINIDFPLA-LFKKLLQQKPSLDDLEELSPVEARSLKNL--LKEDE 791

  Fly   918 GDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKG 982
            ..|..|.|||||...        ||.|.|..|.|...||.:|:.|..|:..|..::.....|.:|
Zfish   792 EVVDLLFLDFTVKGH--------ELVPNGSQIQVNKVNRQKYVDLYVDFVFNKSVKTQFEQFTRG 848

  Fly   983 LSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQ 1047
            .|...|::...||..:|||.|:.|:. ..:.::.::...|.| .|.....|..||.|.....:..
Zfish   849 FSKGCPLDAWTMFHPEELQELLHGSP-QYNWKEFQQSASYEG-CSASDELIKNFWTVFFELSEEH 911

  Fly  1048 RRQLLKFVTSCSRPPLLGF---------KDLDPPFFIQNTGDMERLPTASTCTNLLKLPPFKTVE 1103
            :::.|.|:....|.|..||         :|...|        .:.||.|.||...|.||.:..:.
Zfish   912 KKKFLMFLYGTERVPAGGFSKRRIKISTRDCPDP--------DDHLPKAQTCFGRLVLPKYTDIN 968

  Fly  1104 QMREKLLYAI 1113
            .:|.||.:||
Zfish   969 TLRNKLTHAI 978

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	97/359 (27%)
		HECTc	788..1119	CDD:214523	91/337 (27%)
herc5.2	XP_005160175.1	RCC1_2	120..149	CDD:290274
		RCC1	136..186	CDD:278826
		RCC1	189..238	CDD:278826
		RCC1	242..290	CDD:278826
		RCC1	296..347	CDD:278826
		HECTc	649..985	CDD:294058	97/361 (27%)
		HECTc	678..984	CDD:214523	91/331 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810