Protein Alignment CG3356 and ube3b

DIOPT Version :10

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: NP_001072875.1
• Gene: ube3b / 780337
• XenbaseID: XB-GENE-1010563
• Length: 1072
• Species: Xenopus tropicalis
• Alignment Length: 1194
• Identity: 344/1194 - (28%)
• Similarity: 538/1194 - (45%)
• Gaps: 238/1194 - (19%)

  Fly    31 KAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDGIVEDESLTF--L 93
            ||...|::|..|::::..|:.:|:..|.|:.|.|.::..|:..|.:|.|.:.|.|:..:|:.  :
 Frog    15 KARQAREERKGLKERDRAAIKIQALIRRFLCRCRLQKEIRQEVDDFLEGTEKGSVKANALSIFRI 79

  Fly    94 LRRLNFFYSIREAKDSERLIEVCQQILRQPARLLQHSSPDSLWLLRLCKLLDTCLLQLS------ 152
            .|:|...:.|  ::|..|..::|:.||..    :::.:...:|.:.|....|..||.:.
 Frog    80 SRKLLIIFQI--SQDRMRFEKLCRCILNS----MENDNEPKVWFVSLALSKDLTLLWIKQIKDIL 138

  Fly   153 ---LSHTAQAIP------------LRMLETFT-TVSSVQQYMKDEAV---LFQYMERVFGFLIAR 198
               ..:..|..|            |.||.||| |::......|.|::   :......:.|:|..:
 Frog   139 WYCSEYLKQLKPDILQDSKLITVYLTMLVTFTDTLTWKILKGKGESLRPAMNHICANIMGYLNQK 203

  Fly   199 NYFVRLRRLLDD----KCPPLDGETLHAPSPLAEALLQLLLRPLEVAKRASAGGQMSSMSMAVCR 259
            .::..|:.||.:    ..|.|...||       .||..|.|||:..|:          .|..:.|
 Frog   204 GFYSVLQILLTNGLARSRPSLSKGTL-------TALFSLALRPVVAAQ----------YSDNLLR 251

  Fly   260 NFTRDILATP----HTDPLRYFVLPCFALNVDFPFDLLMRSLYDALESAGPAESDSTSSRRSFLF 320
            :|...|::.|    |...|....|.....|..|...:|..|..|  :.:...|....|.....|.
 Frog   252 SFLIHIMSVPALVSHLSTLTPDRLSVIESNGLFHKFILFLSRED--QCSDVCECLEGSHTLCLLG 314

  Fly   321 YGVETGHKTTRM--------DSIFSSFLLNSLMVLDRRQLATLHQSPLLVIYVRLIAEMMPNILQ 377
            ..:..||.|.::        .|:.:..|......:.:::....|..|:|..:.:.:...:...:.
 Frog   315 NLIHLGHLTEKVLEEEMFHFVSVLTQMLSYCQKYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMP 379

  Fly   378 LPKSTLRGHANAPHRHRDGDDD---SEESEDEDEELPAARTL------DYDMEQTCRTSGELSVK 433
            |....|: |....|..|:...:   .:.:|::|..:|.:::.      :..|:...:.:.:.|..
 Frog   380 LLTKQLQ-HLWGVHMIRNLFREVLSKKLAENQDVSVPVSQSSSSSPQNNLPMKNLFKRAFQKSAS 443

  Fly   434 ERECLLESIAILNETERVDFIVQQLDPHIENTHLIYALCEICHNLMIYNKHAVFEYKLLYTLAFT 498
            .|. :|:.|.    .::||      .|.::.      :|.||               :||.:|.|
 Frog   444 VRH-ILKPIG----GKKVD------SPEVQK------VCNIC---------------VLYQMALT 476

  Fly   499 P------------KFIRAVWFKLAAESTQLGFSAPLTLISKGVVPKHQGVDRTIPLLATFCMLFG 551
            .            .::..:..||.|...:||....|.|..:.:....:...|.:.:|..||....
 Frog   477 TLTQIRLQILTGLTYLDDLLPKLWAFICELGPQGGLKLFLECLSSDTEESRRLLAMLVLFCDCSR 541

  Fly   552 RLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEIIQMSKTL-----KDISMGLVELAFPETR 611
            .|:..|.|:|..|.::              .|.:.|::.:|..|     |.|..||:|.|..||
 Frog   542 HLITILDDIEVYEEQI--------------SFKLEELVTISSFLNSFVFKMIWDGLLENAKGET- 591

  Fly   612 SNLANYRKVLGHTEADDKKLRHQKQIWANLLNVVVFVLNQIHTRDLRLGFCPEDHWTVTRLDLPL 676
                             .:|.|....|          |..::.||.|..|.|||||  .|.||
 Frog   592 -----------------LELFHSVHGW----------LMVLYERDCRRRFAPEDHW--LRKDL-- 625

  Fly   677 DRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENGPPMSTKQIRSITILREIPFVVPFNKRVSILQ 741
             :||.|             ||.: |..|:             |:..:|:.||.|:|...||.:.:
 Frog   626 -KPTLL-------------FQEL-DKERK-------------RAQLLLQYIPHVIPHKNRVLLFR 662

  Fly   742 SLVAASKMRVQGNMQAFLQGPSVL-ITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGLDE 805
            ::|...|.:: |.::.....|.|. ||:|||.:.||.||:||..::..::...|::||:.||:||
 Frog   663 NIVTKEKEKL-GLVETNTASPHVTHITIRRSRMLEDGYDQLRQLSQNAMKGVIRVKFVNDLGVDE 726

  Fly   806 AGIDGGGVFREFLSELIKTAFDPNRGFFMVTTD-NKLYPNPNVADLFEDYEKHYYFIGRILGKSI 869
            ||||..|||:|||.|:||..|||....|..|:. ::|||:| .:.:.|:|.:.:.|:|::|||::
 Frog   727 AGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSSGDRLYPSP-TSYIHENYLQLFEFVGKMLGKAV 790

  Fly   870 YENLLVELPLAEFFLTKLAGK-----YSDVDIHQLASLDPELYRNLLYLKDYSGDVSELNLDFTV 929
            ||.::|::|.|.|||::|.|.     ||.||  :|.|||.|.|:||..:|.|.||:|:|.|..:.
 Frog   791 YEGIVVDVPFASFFLSQLLGHHHSIFYSSVD--ELPSLDSEFYKNLTSIKRYDGDISDLGLTLSY 853

  Fly   930 ASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYM 994
            ....:||....||.|.|:||||||.|:|.|:.|:|.::::.||:....||..|..:::..||:.|
 Frog   854 DEDVMGQLVCHELVPGGKSIPVTNENKISYIHLMAHFRMHTQIKNQTVAFISGFRSIIRPEWIRM 918

  Fly   995 FSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVL-EGFDDMQRRQLLKFVTSC 1058
            ||..|||.||||....|||:|||||..|.|.|...|..|:..|::| ..|...::...|||||||
 Frog   919 FSAPELQRLISGDNAEIDLDDLKKHTVYYGGFHGSHRVIIWLWDILANDFSSEEKAMFLKFVTSC 983

  Fly  1059 SRPPLLGFKDLDPPFFI--------QNTGDM-----------------ERLPTASTCTNLLKLPP 1098
            ||||||||..|.|||.|        |:|||.                 .||||:|||.||||||.
 Frog   984 SRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPN 1048

  Fly  1099 FKTVEQMREKLLYAIQSGAGFELS 1122
            :.....:||||.|||....|||||
 Frog  1049 YSKKGILREKLRYAISMNTGFELS 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	171/385 (44%)
ube3b	NP_001072875.1	IQ	28..50	CDD:197470	6/21 (29%)
		HECTc	686..1070	CDD:238033	171/386 (44%)