Protein Alignment CG3356 and Herc3

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: NP_001348895.1
• Gene: Herc3 / 73998
• MGIID: 1921248
• Length: 1050
• Species: Mus musculus
• Alignment Length: 660
• Identity: 169/660 - (25%)
• Similarity: 271/660 - (41%)
• Gaps: 130/660 - (19%)

  Fly   531 PKHQGVDRTIPLLATFCMLFGRLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEIIQMSKTL 595
            ||..|:|                   |:....:..||:...||.|....|..|....|.|:|.:.
Mouse   453 PKIPGID-------------------LNSTRILFEKLMHSQHSMILEQILNSFESCLIPQLSSSP 498

  Fly   596 KDISMGLVELAFPE------------TRSNLA--------NYRKVLGH--TEADDK--------- 629
            .|:....:.|..||            ....||        |..|||.:  ::|..|
Mouse   499 PDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLETNPSKVLDNWWSQACPKYFMKLVTLY 563

  Fly   630 ------KLRHQKQ-----IWANLLNVVVFVLNQIHTRDLRLGFCPEDHWTVTRLDLPLDRPTD-- 681
                  .||.:|.     ::.|.:...:.:|.:::..:|::.....|.:.:..:...:|...|
Mouse   564 KGAVLYLLRGRKTFLIPVLFNNYMTATLKLLEKLYKVNLKVKHVEYDKFYIPEISSLVDIQEDYL 628

  Fly   682 LPLTHSSRLRGIRPFQPIRDFTREDFENGPPMSTKQIRSITILREIPFVVPFNKRVSILQSLVAA 746
            :...|.|.::. ||                    ..::....|...||:.....:..:||: .|.
Mouse   629 MWFLHQSGMKA-RP--------------------SIMQDAVTLCSYPFIFDAQAKTKMLQT-DAE 671

  Fly   747 SKMRVQ---GNMQ-AFL---------QGPSVLITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFV 798
            .:|:|.   .|:| .|:         :.|.:::.|||:||..||..:|...::.||:...::.|.
Mouse   672 LQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNHLVGDALRELSIHSDIDLKKPLKVIFD 736

  Fly   799 SSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDNKLYPNPNVADLFED--YEKHYYF- 860
            .     |.|:|.|||.:||...|:|...:|..|.|....|:.|.       .|.|  :.:|.:|
Mouse   737 G-----EEGVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLL-------WFSDTCFVEHNWFH 789

  Fly   861 -IGRILGKSIYENLLVEL--PLAEFFLTKLAGKYSDV--DIHQLASLDPELYRNLLYLKDYSG-D 919
             ||...|.:||.:.:|:|  |||      |..|..:|  .:..|..|.|...|:|..|.||.| |
Mouse   790 LIGITCGLAIYNSTVVDLHFPLA------LYKKLLNVKPSLEDLKELSPTEGRSLQELLDYPGED 848

  Fly   920 VSE-LNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGL 983
            :.| ..|:|||...|.|..:..:|.|.|..:.|...||.|::....:|...:.:.....||..|.
Mouse   849 IEETFCLNFTVCRESYGVIEQKKLIPGGDRVAVCKDNRQEFVDAYVNYIFQISVHEWYTAFSSGF 913

  Fly   984 SNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQR 1048
            ..|...:.|.:|...||:.::.| ....|.|:|::...|.|::|..||::..|||....|...::
Mouse   914 LKVCGGKVLELFQPAELRAMMVG-NSNYDWEELEETAVYRGDYSSTHPTVKLFWETFHEFPLEKK 977

  Fly  1049 RQLLKFVTSCSRPPLLGFKDLDPPFFIQNTGDMER-LPTASTCTNLLKLPPFKTVEQMREKLLYA 1112
            ::.|.|:|...|.|:.|...|.  ..||:|...|. ||.|.||.|||.||.:.:.|.|:.:|..|
Mouse   978 KKFLLFLTGSDRIPIYGMASLQ--IIIQSTATGEEYLPVAHTCYNLLDLPKYSSKEIMKARLTQA 1040

  Fly  1113 IQSGAGFELS 1122
            :.:..||.|:
Mouse  1041 LDNYEGFSLA 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	115/364 (32%)
		HECTc	788..1119	CDD:214523	106/341 (31%)
Herc3	NP_001348895.1	ATS1	2..331	CDD:227511
		RCC1	313..377	CDD:366085
		HECTc	702..1048	CDD:238033	115/366 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810