Protein Alignment CG3356 and Ube3b

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: NP_001137366.1
• Gene: Ube3b / 687633
• RGDID: 1583074
• Length: 1070
• Species: Rattus norvegicus
• Alignment Length: 1221
• Identity: 355/1221 - (29%)
• Similarity: 526/1221 - (43%)
• Gaps: 294/1221 - (24%)

  Fly    31 KAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDGIVEDESLTF--L 93
            ||...|::|.|.:::|..||::|:..|||:.|:|..:..|...|.:....:.|..:..:|..  :
  Rat    15 KARQAREERLEQKERERSAVLIQALVRSFLCRRRLHKDVRREIDEFFTADESGSSKRSALCIFKI 79

  Fly    94 LRRLNFFYSIREAKDSERLIEVCQQILRQPARLLQHSSPDS-------------------LWLLR 139
            .|:|.|.  .:..:|:||:.::|:.||         ||.|:                   ||:.:
  Rat    80 ARKLLFI--CKTTEDNERMEKLCRSIL---------SSMDAENEPKVWYVSLALSKDLTLLWIKQ 133

  Fly   140 L-------CKLLDTCLLQLSLSHTAQAIPLRMLETFTTVSSVQQYM-KDEAV---LFQYMERVFG 193
            :       |:||.....::........:.|.||.|||..|:.:... |.|::   |......:.|
  Rat   134 IKSILWYCCELLGQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPALNHICANIMG 198

  Fly   194 FLIARNYF----VRLRRLLDDKCPPLDGETLHAPSPLAEALLQLLLRPLEVAKRASAGGQMSSMS 254
            .|..|.::    |.|.|.|....|.|...||.|...||       |||:..|:          .|
  Rat   199 HLNQRGFYSVLQVLLTRGLARPRPCLSKSTLTAAFTLA-------LRPVVAAQ----------FS 246

  Fly   255 MAVCRNFTRDILATP----HT--------------DPLRYFVL----------PCFALNVDFPFD 291
            .::.|.|...|::.|    |.              |.||.|::          .|.:|.......
  Rat   247 DSLMRPFIIHIMSVPALVAHLSTMAPERLGVLESHDMLRKFIVFLRDRDRCQDACESLEGCHTLC 311

  Fly   292 LLMRSLY------DALESAGPAESDS---------------TSSRRSFLFYGVETGHKTTRMDSI 335
            |:...|:      ..||.    |:|.               .|.::|.|.:    .|......|.
  Rat   312 LMGNLLHLGSLNLKMLEE----ETDGFVSLLTQMLCYCQKYVSQKKSNLTH----WHPVLGWFSQ 368

  Fly   336 FSSFLLNSLMVLDRRQLATLHQSPLLVIYVRLIAEMMPNILQLPKSTLRGHANAPHRHRDGDDDS 400
            ...:.||..|.|..:||..|...||:.|:...|  :...:|:.|
  Rat   369 SVDYGLNDSMYLITKQLQFLWGVPLIRIFFSDI--LSKKLLEPP--------------------- 410

  Fly   401 EESEDEDEELPAARTLDYDMEQTCRTSGELSVKE--RECLLESIAILNETERVDFIVQQLDPHIE 463
                   |.:||       ..|.......|.||.  :....:|.::.|..:.|.      ...::
  Rat   411 -------EPVPA-------QPQPSSPQTVLPVKSLLKRAFQKSASVRNILKPVG------GRRVD 455

  Fly   464 NTHLIYALCEICHNLMIYNKHAV----FEYKLLYTLAFTPKFIRAVWFKLAAESTQLGFSAPLTL 524
            :|. :..:|.||   ::|.....    ...::|..|.:....:..:|    |...:||....|.|
  Rat   456 STE-VRKVCSIC---VLYQTSLTTLTQIRLQILTGLTYLDDLLPKLW----AFICELGPHGGLKL 512

  Fly   525 ISKGVVPKHQGVDRTIPLLATFCMLFGRLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEII 589
            ..:.:........:.:.:|..||.....|:..|.|:|..|.::              .|.:.|::
  Rat   513 FLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQI--------------SFKLEELV 563

  Fly   590 QMSKTL-----KDISMGLVELAFPETRSNLANYRKVLGHTEADDKKLRHQKQIWANLLNVVVFVL 649
            .:|..|     |.|..|:||.|..||   |..::.|.|               |          |
  Rat   564 TISSFLNSFVFKMIWDGIVENAKGET---LELFQSVHG---------------W----------L 600

  Fly   650 NQIHTRDLRLGFCPEDHWTVTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENGPPMS 714
            ..::.||.|..|.|||||  .|.||   :|..|             ||.: |..|:
  Rat   601 MVLYERDCRRRFAPEDHW--LRKDL---KPGVL-------------FQEL-DKDRK--------- 637

  Fly   715 TKQIRSITILREIPFVVPFNKRVSILQSLVAASKMRVQGNMQAFLQGPSVL-ITVRRSHLYEDAY 778
                |:..||..||.|||...||.:.:::|...|.:: |.::.....|.|. ||:|||.:.||.|
  Rat   638 ----RAQLILLHIPHVVPHKNRVLLFRNMVIKEKEKL-GLVETSSASPHVTHITIRRSRMLEDGY 697

  Fly   779 DKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTT-DNKLY 842
            ::||...:..::...|::|||.||:||||||..|||:|||.|:||..|||....|..|: |.:||
  Rat   698 EQLRQLPQHAMKGAIRVKFVSDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLY 762

  Fly   843 PNPNVADLFEDYEKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGK-----YSDVDIHQLASL 902
            |:| .:.:.|:|.:.:.|:|::|||::||.::|::|.|.|||:::.|.     ||.||  :|.||
  Rat   763 PSP-TSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSVFYSSVD--ELPSL 824

  Fly   903 DPELYRNLLYLKDYSGDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYK 967
            |.|.|:||..:|.|.|||::|.|..:.....:||....||.|.|::||||:.|:|.|:.|:|.::
  Rat   825 DSEFYKNLTSIKRYDGDVADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFR 889

  Fly   968 LNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPS 1032
            ::.||:....|...|..:::..||:.|||..|||.||||....|||||||||..|.|.|...|..
  Rat   890 MHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRV 954

  Fly  1033 IVTFWEVL-EGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPPFFI--------QNTGDM------- 1081
            ||..|::| ..|...:|...|||||||||||||||..|.|||.|        |:|||.
  Rat   955 IVWLWDILASDFTPGERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRG 1019

  Fly  1082 ----------ERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGFELS 1122
                      .||||:|||.||||||.:.....:||||.|||....|||||
  Rat  1020 FFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	171/385 (44%)
		HECTc	788..1119	CDD:214523	160/362 (44%)
Ube3b	NP_001137366.1	HECTc	684..1068	CDD:238033	171/386 (44%)
		HECTc	709..1067	CDD:214523	160/360 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1163565at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100865
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720