DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3356 and Wwp2

DIOPT Version :9

Sequence 1:NP_611896.1 Gene:CG3356 / 37876 FlyBaseID:FBgn0034989 Length:1122 Species:Drosophila melanogaster
Sequence 2:NP_080106.1 Gene:Wwp2 / 66894 MGIID:1914144 Length:870 Species:Mus musculus


Alignment Length:370 Identity:120/370 - (32%)
Similarity:189/370 - (51%) Gaps:26/370 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   762 PS-VLITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTA 825
            || |.|:|.|..|:||::.::......|||   |..::...|  |.|:|.||:.||:...|....
Mouse   512 PSHVKISVSRQTLFEDSFQQIMNMKPYDLR---RRLYIIMRG--EEGLDYGGIAREWFFLLSHEV 571

  Fly   826 FDPNRGFFMVTTDNK--LYPNPNVADLFEDYEKHYYFIGRILGKSIYENLLVE----LPLAEFFL 884
            .:|....|.....|.  |..|| .:.:..|:..::.||||.:..::|....::    ||..:..|
Mouse   572 LNPMYCLFEYAGKNNYCLQINP-ASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRML 635

  Fly   885 TKLAGKYSDVDIHQLASLDPELYRNLLYLKDYSGDVSELNLDFTVASSSLGQTQIVELKPQGQSI 949
            .|..      .:..|.|:|||.|.:::::|:.:.:...|.|.|......||:....|||..|::|
Mouse   636 NKRP------TLKDLESIDPEFYNSIVWIKENNLEECGLELFFIQDMEILGKVTTHELKEGGENI 694

  Fly   950 PVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLE 1014
            .||..|:.||:.|:.|::....:.....||..|.:.|.|:|||..|..|||::::.|.: .||:.
Mouse   695 RVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQ-EIDMS 758

  Fly  1015 DLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDL-----DPPFF 1074
            |.:|:..| ..::.....|..||:|::..|:.:|.:||:|||...|.|:.||.:|     ...|.
Mouse   759 DWQKNAIY-RHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFC 822

  Fly  1075 IQNTGDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGF 1119
            |...|....||.:.||.|.|.|||:|:.||::|||||||:...||
Mouse   823 IDRVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGF 867

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3356NP_611896.1 HECTc 766..1120 CDD:238033 117/365 (32%)
HECTc 788..1119 CDD:214523 109/341 (32%)
Wwp2NP_080106.1 C2_E3_ubiquitin_ligase 17..142 CDD:175988
PRK07003 <149..>299 CDD:235906
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 150..300
WW 302..331 CDD:366073
WW 332..361 CDD:366073
WW 407..435 CDD:366073
WW 447..477 CDD:238122
HECTc 516..868 CDD:238033 117/366 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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