Protein Alignment CG3356 and ube3b

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: NP_001108154.1
• Gene: ube3b / 556864
• ZFINID: ZDB-GENE-060526-231
• Length: 1069
• Species: Danio rerio
• Alignment Length: 1206
• Identity: 341/1206 - (28%)
• Similarity: 524/1206 - (43%)
• Gaps: 265/1206 - (21%)

  Fly    31 KAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDGIVEDESLTF--L 93
            ||.:.|::|...::||..|..:|:..|.|:.|.|.::..|:..|.::.....|..:..:|:.  :
Zfish    15 KARVAREERKGHKEKERAATQIQALVRRFLCRCRLQKEIRKEVDDFIAVSDAGPTKRNALSIFKI 79

  Fly    94 LRRLNFFYSIREAKDSE-RLIEVCQQIL------RQP----ARLLQHSSPDSLWLLRL------- 140
            .|:|.|..|    ||.: |..::|:.||      .:|    ..|........|||.::
Zfish    80 ARKLLFILS----KDDKLRFEKLCRIILNSMDVENEPKVWYVSLALSKDLTILWLKQIKDVLWVS 140

  Fly   141 CKLLDTCLLQLSLSHTAQAIPLRMLETFTTVSSVQQYM-KDEAV---LFQYMERVFGFLIARNYF 201
            |:.|......:...:....:.|.||.|||..|:.:... |.||:   |.:..|.:.|.|..:.::
Zfish   141 CEFLKKLKPDILQDNKLVTLYLTMLITFTDTSTWKIIRGKGEALKPALNRICENIMGHLNQKGFY 205

  Fly   202 VRLRRLLDD----KCPPLDGETLHAPSPLAEALLQLLLRPLEVAKRASAGGQMSSMSMAVCRNFT 262
            ..|:.||.:    ..|.|...||       .|:..|.|||:..|          ..|..:.|:|.
Zfish   206 SVLQILLTNGLARSRPSLSKGTL-------TAIFTLSLRPVIAA----------HFSDNLLRSFL 253

  Fly   263 RDILATP----HTDPL--------------RYFVL----------PCFALNVDFPFDLLMRSL-- 297
            ..:::.|    |.:.|              |.|||          .|..|.......||...:
Zfish   254 LHVMSVPAFISHLNTLTPDCMITIQTHDLFRKFVLFLSREEQCLDICVCLEGSHTLCLLGNLIQL 318

  Fly   298 ----YDALE-SAGPAESDST----------SSRRSFLFYGVETGHKTTRMDSIFSSFLLNSLMVL 347
                ...|| .||....|.|          |.::|.|.:    .|......|....:.||..|.|
Zfish   319 GYFNVKVLEQEAGHFVKDLTDMLSYCQRYVSQKKSNLTH----WHPVLGWFSQTVDYGLNESMPL 379

  Fly   348 DRRQLATLHQSPLLVIYVRLIAEMMPNILQLPKSTLRGHANAPHRHRDGDDDSEESEDEDEELPA 412
            ..:||..|...|       :|..:..::|                       |::.|.:|...|.
Zfish   380 VTKQLQCLWGVP-------VICTLFCDVL-----------------------SKKLETQDPTPPP 414

  Fly   413 ARTLDYDMEQTCRTSGELSVKE--RECLLESIAILNETERVDFIVQQLDPHIENTHLIYALCEIC 475
            |       .|.......|.||.  :....:|.::.|       |::.:.....::..:..:|.||
Zfish   415 A-------PQPSSLQNNLPVKNLFKRAFQKSASVRN-------ILKPVGGKRVDSAEVQKVCSIC 465

  Fly   476 HNLMIYNKHAV----FEYKLLYTLAFTPKFIRAVWFKLAAESTQLGFSAPLTLISKGVVPKHQGV 536
               ::|.....    ...::|..|.:..:.:..:|    |...:||....|.|..:.:....:..
Zfish   466 ---VLYQTALTTLTQIRLQILTGLTYLDELLPKLW----AFICELGPQGGLRLFLECLNNDTEES 523

  Fly   537 DRTIPLLATFCMLFGRLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEIIQMSKTLKDISMG 601
            .:.:.:|..||.....|:..|.|:|..|.::              .|.:.|::.:|..|......
Zfish   524 KQLLAMLMLFCDCSRHLITILDDIEVYEEQI--------------SFKMEELVTISSFLNTFVYK 574

  Fly   602 LVELAFPETRSNLANYRKVLGHTEADDKKLRHQKQIWANLLNVVVFVLNQIHTRDLRLGFCPEDH 666
            :|             :..:|.:.:.:...|.|....|          |..::.||.|..|.||||
Zfish   575 MV-------------WDGILENAKGEKLDLFHSVHGW----------LMVLYERDCRRRFTPEDH 616

  Fly   667 WTVTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENGPPMSTKQIRSITILREIPFVV 731
            |  .|.||   :|:.|             ||        :.|.|      :.|:..:|:.||.|:
Zfish   617 W--LRKDL---KPSLL-------------FQ--------ELEKG------KKRAQLLLQYIPHVI 649

  Fly   732 PFNKRVSILQSLVAASKMRVQGNMQAFLQGPSVL-ITVRRSHLYEDAYDKLR--PDNEPDLRFKF 793
            |...||.:.:::|...| ...|.::.....|.|. ||:|||.:.||.||:||  |.|  .::...
Zfish   650 PHKNRVLLFRNIVTKEK-ETLGLVETSSASPHVTHITIRRSRMLEDGYDQLRRLPVN--SIKGVI 711

  Fly   794 RIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDN-KLYPNPNVADLFEDYEKH 857
            |::||:.||:||||||..|||:|||.|:||..|:|....|..|:.| :|||:| .:.:.|::.:.
Zfish   712 RVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNERLYPSP-TSSIHENHLQL 775

  Fly   858 YYFIGRILGKSIYENLLVELPLAEFFLTKLAGK-----YSDVDIHQLASLDPELYRNLLYLKDYS 917
            :.|:|::|||::||.::|::|.|.|||:::.|.     ||.:|  :|.|||.|.|:||..:|.|.
Zfish   776 FEFVGKMLGKAMYEGIVVDVPFASFFLSQVLGHHHSTFYSSID--ELPSLDSEFYKNLTSIKRYD 838

  Fly   918 GDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKG 982
            ||||:|.|..:.....:||....||.|.|:::||||.|:|.|:.|:|.::::.||:....||.:|
Zfish   839 GDVSDLGLTLSYDEEVMGQLVCHELIPGGKTMPVTNENKISYIHLMAHFRMHTQIKEQTAAFIRG 903

  Fly   983 LSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEG-FDDM 1046
            ..:::..|||:|||..|:|.||||....|||:|||||..|.|.|...|..|:..|::|.. |...
Zfish   904 FRSIINPEWLHMFSTPEVQRLISGDNAEIDLDDLKKHTVYYGGFHSSHRVILWLWDILSSDFTPD 968

  Fly  1047 QRRQLLKFVTSCSRPPLLGFKDLDPPFFI--------QNTGDM-----------------ERLPT 1086
            :|...|||||||||||||||..|.|||.|        |:|||.                 .||||
Zfish   969 ERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPT 1033

  Fly  1087 ASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGFELS 1122
            :|||.||||||.:.....:|:||.|||....|||||
Zfish  1034 SSTCFNLLKLPNYSKKSILRDKLRYAISMNTGFELS 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	169/387 (44%)
		HECTc	788..1119	CDD:214523	155/362 (43%)
ube3b	NP_001108154.1	IQ	28..50	CDD:197470	8/21 (38%)
		HECTc	683..1067	CDD:238033	169/388 (44%)
		HECTc	708..1066	CDD:214523	155/360 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1163565at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100865
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1831
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750