Protein Alignment CG3356 and smurf1

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: NP_001001943.1
• Gene: smurf1 / 321695
• ZFINID: ZDB-GENE-040426-2744
• Length: 731
• Species: Danio rerio
• Alignment Length: 568
• Identity: 163/568 - (28%)
• Similarity: 251/568 - (44%)
• Gaps: 127/568 - (22%)

  Fly   622 GHTEADDKKLRHQKQIWANLLNVVVFVLNQIH---TRDLRLGFCPEDHWTVTRLDLPLDRPTDLP 683
            |||        |..|             |:.|   :.||..|:  |...||......|...|.:.
Zfish   218 GHT--------HTPQ-------------NRPHGHQSPDLPEGY--EQRTTVQGQVYFLHTQTGVS 259

  Fly   684 LTHSSRLRGIRPFQPIRDFTREDFEN-GPPMSTKQIRSITILREIPFVVPFNKRVSILQSL---V 744
            ..|..|:.        ||......|. ||....::||| |:...|.||...|:........   :
Zfish   260 TWHDPRIP--------RDLNSVSCEELGPLPPGREIRS-TVSGRIYFVDHNNRTTQFTDPRLHHI 315

  Fly   745 AASKMRVQGNMQAF-----------------------------------LQGPSV---LITVRRS 771
            .:...:|:.:.||.                                   ||.|..   .|.|.|.
Zfish   316 MSQHSQVKESSQALPVQMEVGMEEGDGELPVRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSRE 380

  Fly   772 HLYEDAYD---KLRP-DNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGF 832
            .::|::|.   |:|| |.:..|..|||         .|.|:|.|||.||:|..|.....:|..|.
Zfish   381 EIFEESYRQIMKMRPKDLKKRLMVKFR---------GEEGLDYGGVAREWLYLLCHEMLNPYYGL 436

  Fly   833 FMVTTDN--KLYPNPNVADLFEDYEKHYYFIGRILGKSIYENLLVE----LPLAEFFLTKLAGKY 891
            |..:|||  .|..||: :.:..|:..:::|:|||:|.:::....:.    ||    |..:|.||
Zfish   437 FQYSTDNIYTLQINPD-SSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTLP----FYKQLLGK- 495

  Fly   892 SDVDIHQLASLDPELYRNLLYLKDYSGDV-SELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSN 955
             .:.:..|.::||||:::|:::.:  .|: |.|:..|.|..::.|:....||||.|::||||..|
Zfish   496 -PIQLCDLETVDPELHKSLVWILE--NDITSVLDHTFCVEHNAFGKFLQHELKPNGKNIPVTEEN 557

  Fly   956 RIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLK--- 1017
            :.||::|..:::....|.....|.:||.:.::|...|..|.||||:::|.|.. .|||.|.|
Zfish   558 KKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDNKELELIIGGLG-KIDLNDWKANT 621

  Fly  1018 --KHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLD-------PPF 1073
              |||......      :..||:.:|.||:.:|.:||:|||..:|.||.|||.|.       |..
Zfish   622 RLKHCVADSNI------VKWFWQAVESFDEERRGRLLQFVTGSTRVPLQGFKALQGSTGSAGPRL 680

  Fly  1074 FIQNTGD--MERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGF 1119
            |..:..|  .:.||.|.||.|.:.:||:::.|::.||||.|::...||
Zfish   681 FTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGF 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	127/379 (34%)
		HECTc	788..1119	CDD:214523	116/351 (33%)
smurf1	NP_001001943.1	C2_Smurf-like	14..138	CDD:176028
		WW	234..266	CDD:197736	9/33 (27%)
		WW	280..312	CDD:197736	9/32 (28%)
		HECTc	373..728	CDD:238033	125/379 (33%)
		HECTc	397..728	CDD:214523	117/355 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810