Protein Alignment CG3356 and Trip12

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: XP_038939619.1
• Gene: Trip12 / 316575
• RGDID: 1306607
• Length: 2074
• Species: Rattus norvegicus
• Alignment Length: 1430
• Identity: 297/1430 - (20%)
• Similarity: 482/1430 - (33%)
• Gaps: 486/1430 - (33%)

  Fly    26 DTVIRKAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDGIVEDE-S 89
            ||:::|..         .|..:||:......|...|..  .|.:..:.::  ..|:.|  ||| |
  Rat   798 DTMLKKGN---------AQNTDGAIWQWRDDRGLWHPY--NRIDSRIIEV--AAHQVG--EDEIS 847

  Fly    90 LTFLLR----RLNFFYSIREAKDSERLIEVCQQILRQP--------------------ARLLQHS 130
            |:.|.|    ..|....|.|...:.|.|:      |:|                    |:|::.
  Rat   848 LSTLGRVYTIDFNSMQQINEDTGTARAIQ------RKPNPLANTNTSGYSDLKKDDARAQLMKE- 905

  Fly   131 SPDSLWLLRLCKLLDTCLLQLSLSHTAQAIPLRMLET------FTTVSSVQQYMKDEAV------ 183
              |........|.|...|.::..|....|:..:.|..      |.....::..:|:.||
  Rat   906 --DPELAKSFIKTLFGVLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIAS 968

  Fly   184 --LFQYMERVFGFLIARNYFVRLRRLLDDKCPPL-------DGETLHAPSPLAEALLQLLLRPLE 239
              ..|.::.|.|.|       ::..:|..|.|.:       :| .:|....|||: ..||..|.:
  Rat   969 MLSSQDLKIVVGAL-------QMAEILMQKLPDIFSVYFRREG-VMHQVKHLAES-ESLLTSPPK 1024

  Fly   240 VAKRASAGGQMSSMSMAVCRNFTRDILATPHTDPLRYFVLPCFALNVDFPFDLLMRS-LYDALES 303
            .....|  |.:.|.:.|....      ||..|:.......|....:.|...||..:. |.|.|:.
  Rat  1025 ACTNGS--GSLGSTTPASSGT------ATAATNASADLGSPSLQHSRDDSLDLSPQGRLSDVLKR 1081

  Fly   304 -------------AGPAESDSTSSRRSFLFYGVETGHKTTRMDSIFSSFLLNSLMVLDRRQLATL 355
                         :.|.:.|...::          ....|...|..|||            ||:|
  Rat  1082 KRLPKRGPRRPKYSPPRDDDKVDNQ----------AKSPTTTQSPKSSF------------LASL 1124

  Fly   356 HQSPLLVIYVRLIAEMMPNILQLPKSTLRGHANAPHRHRDGDDDSEE------------------ 402
            :..    .:.||.|:...|.:: |..|......|....:|...::.|
  Rat  1125 NPK----TWGRLSAQSNSNNIE-PARTAGVSGLARAASKDTISNNREKIKGWIKEQAHKFVERYF 1184

  Fly   403 -SEDEDEELPAARTLDYDMEQTCRTSGELSVK---ERECLLESIAILNETERVDFIVQQLDPHIE 463
             ||:.|...||...|    ::.|..:.:|:::   ..|||:|..:|::|::...|.:|
  Rat  1185 SSENMDGSNPALNVL----QRLCAATEQLNLQVDGGAECLVEIRSIVSESDVSSFEIQ------- 1238

  Fly   464 NTHLIYALCEICHNLMIYNKHAVF-EYKLLYTLAFTPK--FIRAVWFKLAAESTQLGFSAPLTLI 525
                                |:.| :..|||..:.:.|  ..|.:..|   ....:.||:||
  Rat  1239 --------------------HSGFVKQLLLYLTSKSEKDAVSREIRLK---RFLHVFFSSPL--- 1277

  Fly   526 SKGVVPKHQGVDRT-----IPLLATF-----CMLFGRLLPT-LHD-------------------V 560
                 |..:.|.|.     .||||..     |:......|. :||                   :
  Rat  1278 -----PGEEPVGRVEPVGHAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGSGGSFSLNRGSQAL 1337

  Fly   561 EFVEN---KLLLQVHSTINH--------VRLMPFSIAEIIQMSKTLKDISMGLVELAFPETRSNL 614
            :|...   |..||.|....:        |::.|.::.:.|:....::.|
  Rat  1338 KFFNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGI---------------- 1386

  Fly   615 ANYRKVL---------GHTEADDKKL----------RHQKQ--IWANLL--NVVVF-VLNQ--IH 653
            ..|.:|.         |..|..|:.|          ||:.|  |..:||  |:.|: .:.|  :.
  Rat  1387 FRYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSVQ 1451

  Fly   654 TRDLRLGFCPEDHWTVTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENG-------- 710
            ..|.|.....|.:        ||.|......||:..      ::|:    |||.|:.
  Rat  1452 AEDERESTDDESN--------PLGRAGIWTKTHTIW------YKPV----REDEESSKDCVGGKR 1498

  Fly   711 ----------PPMSTKQIRSI-------------------TILREIPFVVPFNKRVSILQSLVAA 746
                      .|.:.|:...:                   |....|.|..|....:.:|:.|.|.
  Rat  1499 GRAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPTPPENITFEDPSLDVILLLRVLHAI 1563

  Fly   747 ------------------------SKMRVQGNMQAFLQGPSVLIT-------------------- 767
                                    ||:..:.|.|  ||.|.|::|
  Rat  1564 SRYWYYLYDNAMCKEIIPTSEFINSKLTAKANRQ--LQDPLVIMTGNIPTWLTELGKTCPFFFPF 1626

  Fly   768 -VRRSHLYEDAYDKLRP-----DNEPDL---------------RFKFRIQFVSSLGLDEAGIDGG 811
             .|:...|..|:|:.|.     |..|::               |.|..:.....|...|:.:...
  Rat  1627 DTRQMLFYVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDL 1691

  Fly   812 GVFREFL----SELIKTAFDPNRGFFMVTT-------------DNKLYPNP-----------NVA 848
            |..|..|    ...:.|...|...|:.:.:             :.....||           |:.
  Rat  1692 GSSRAMLEIQYENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQ 1756

  Fly   849 DLF-------------EDYEKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGKYSDVDIHQLA 900
            .||             ...:..:.|:|:::.|:|.:..||:|||...|...:..:.:.:..|.|.
  Rat  1757 GLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLF 1821

  Fly   901 SLDPELYRNLLYLKD---------------------------YSG-DVSELNLDFTVASSSLGQT 937
            .:||.:.|::.:|:|                           .:| .|.:|.||||     |...
  Rat  1822 DIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFT-----LPGF 1881

  Fly   938 QIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQI 1002
            ..:|||..|:.||||..|..|||:|:..:.||..:.|..::||.|..:|.|:..|..|..:||..
  Rat  1882 PNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFESVFPLSHLQYFYPEELDQ 1946

  Fly  1003 LISGAEIPI-DLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGF 1066
            |:.|::... |.:.|.:.|.....::.:..::...:|:|..||:.|:|..|:|||...|.|:.||
  Rat  1947 LLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGF 2011

  Fly  1067 KDLDPPFFI--------QNTGDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSG-AGFELS 1122
            :.|:||..|        :|..|.  ||:..||.|.||||.:.::|.||:|||.|.:.| ..|.||
  Rat  2012 RSLNPPLTIVRKTFESTENPDDF--LPSVMTCVNYLKLPDYSSIEIMRDKLLIAAREGQQSFHLS 2074

  Fly  1123  1122
              Rat  2075  2074

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	115/473 (24%)
		HECTc	788..1119	CDD:214523	107/424 (25%)
Trip12	XP_038939619.1	SRP1	489..>714	CDD:227396
		WWE	814..876	CDD:397111	16/67 (24%)
		HECTc	1672..2072	CDD:238033	106/406 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900