Protein Alignment CG3356 and Hectd3

DIOPT Version :10

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: NP_001386141.1
• Gene: Hectd3 / 313525
• RGDID: 1309823
• Length: 861
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 145/591 - (24%)
• Similarity: 233/591 - (39%)
• Gaps: 124/591 - (20%)

  Fly   605 LAFPETRSNLANYRKVLGHTEADDKKLRHQKQIWANLL-NVVVFVLNQIH--TRDLRLGFCPEDH 666
            |....|..|....|.|:...|.|:.|......|...|: :|.|.....:|  ..::|:..|.:|.
  Rat   296 LTVDTTDDNFMPKRVVVYGGEGDNLKKLSDVNIDETLIGDVCVLEDMTVHLPVIEIRIVECRDDG 360

  Fly   667 WTV------------TRLDLPLDRPTDLPLTHSSRLRGIRP------------FQPIRDFTRE-- 705
            ..|            ..|.|..|......|....||.|..|            |..|.|....
  Rat   361 IDVRLRGVKIKSSRQRELGLNADLFQPASLVRYPRLEGTDPEVLYRRAVLLQRFIKILDSVLHHL 425

  Fly   706 ----DFENGPPMSTKQIRSITIL-REIPFVVPFNKRVSILQSLVAASKMRVQGNMQAFLQGPSVL 765
                |...|.....||::...:| |:.|             |||.......:.:..:|:  |.:.
  Rat   426 VPAWDHTLGTFSEIKQVKQFLLLSRQRP-------------SLVTQCLRDSESSKPSFM--PRLY 475

  Fly   766 ITVR---------------RSHLYEDAYDKLRPDN---EP-DLRFKFRI-QFVSSLGLDEAGIDG 810
            |..|               ::.::...|:.|:|.:   :| |.|:..|. |:.....:.|..||.
  Rat   476 INRRLAMEHRACPSRDPACKNAVFTQVYEGLKPSDKYEKPLDYRWPMRYDQWWECKFIAEGIIDQ 540

  Fly   811 GGVFREFLSELIK-----TAFDPNRGFFMVTTDNK---------LY-PNPNVADLFEDYEKHYYF 860
            ||.||:.|:::.:     :|..|....|.|.|.|:         :| |||:..| |..||    :
  Rat   541 GGGFRDSLADMSEELCPSSADTPVPLPFFVRTANQGNGTGEARDMYVPNPSCRD-FAKYE----W 600

  Fly   861 IGRILGKSIYENLLVELPLAEFFLTKLAGKYSDVD-IHQLASLDPELYRNLLYLKDYSGDVSEL- 923
            ||:::|.::.....:.|.|..|...:|:|:  :|. .....::|..|.:.|..::....:..|.
  Rat   601 IGQLMGAALRGKEFLVLALPGFVWKQLSGE--EVSWSKDFPAVDSVLVKLLEVMEGVDKETFEFK 663

  Fly   924 ---NLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSN 985
               .|.||..   |...|:|||.|.|..|.|...:|:.::||:...:|. :.:....|.:.||..
  Rat   664 FGKELTFTTV---LSDQQVVELIPGGTGIVVGYEDRLRFIQLVQKARLE-ESKEQVAAMQAGLLK 724

  Fly   986 VLPIEWLYMFSNKELQILISG-AEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRR 1049
            |:|...|.:.:.:||:..:.| .|:.:|.  |:|...: .:|.|....:..|||.|..|.:..|.
  Rat   725 VVPQAVLDLLTWQELEKKVCGDPEVTVDA--LRKLTRF-EDFEPSDTRVQYFWEALNNFTNEDRS 786

  Fly  1050 QLLKFVTSCSR--------PPLLGFKDLDPPFFIQNTGDMERLPTASTCTNLLKLPPFKTVEQMR 1106
            :.|:|||..||        |..||::..|            .||.:|||::.|.||.:.:.:...
  Rat   787 RFLRFVTGRSRLPARIYIYPDKLGYETTD------------ALPESSTCSSTLFLPHYASAKVCE 839

  Fly  1107 EKLLYA 1112
            |||.||
  Rat   840 EKLRYA 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	105/396 (27%)
Hectd3	NP_001386141.1	APC10-HECTD3	238..371	CDD:176487	17/74 (23%)
		HECT	579..845	CDD:459880	79/291 (27%)