DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3356 and Bag3

DIOPT Version :9

Sequence 1:	NP_611896.1	Gene:	CG3356 / 37876	FlyBaseID:	FBgn0034989	Length:	1122	Species:	Drosophila melanogaster
Sequence 2:	NP_038891.4	Gene:	Bag3 / 29810	MGIID:	1352493	Length:	577	Species:	Mus musculus

Alignment Length:	131	Identity:	28/131 - (21%)
Similarity:	45/131 - (34%)	Gaps:	31/131 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 GHKTTRMDSIFSSFLLNSLMVLD-------------RRQ--------LATLHQSPLLVIYVRLIA 369
            |.||.:...:...:|...|:.||             ||.        |..|.|..:.|.....:.
Mouse   449 GKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVY 513

  Fly   370 EMMPNILQL--PKSTLRGHANAPHRHRDGDDDSEESED---EDEELPAARTLDYDMEQTCRTSGE 429
            |:.|:.|:.  |...:.|...|     |.|....|::|   |.::|.|......:......::|.
Mouse   514 ELQPSNLEAEQPLQEIMGAVVA-----DKDKKGPENKDPQTESQQLEAKAATPPNPSNPADSAGN 573

  Fly   430 L 430
            |
Mouse   574 L 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033
CG3356	NP_611896.1	HECTc	788..1119	CDD:214523
Bag3	NP_038891.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..81
		WW	23..55	CDD:197736
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	126..207
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	229..427
		BAG	426..503	CDD:214591	12/53 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..577		12/56 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900