DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3356 and Wwtr1

DIOPT Version :9

Sequence 1:	NP_611896.1	Gene:	CG3356 / 37876	FlyBaseID:	FBgn0034989	Length:	1122	Species:	Drosophila melanogaster
Sequence 2:	NP_001020040.1	Gene:	Wwtr1 / 295062	RGDID:	1559609	Length:	395	Species:	Rattus norvegicus

Alignment Length:	209	Identity:	44/209 - (21%)
Similarity:	65/209 - (31%)	Gaps:	74/209 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   586 AEIIQMSKTLKDISMGLVELAFP---ETRSNLANYRKVLGHTE-----ADDKKLRHQKQIWANLL 642
            |.:.|.|..:.|      ||..|   |........|..|.|.|     .|.:|:.:|.....||.
  Rat   111 AHLRQQSYDVTD------ELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKVMNQPLNHVNLH 169

  Fly   643 NVVV---------------FVLNQIHTRDLRLGFCPEDHWTVTRLDLPLDR-PTDL-----PLT- 685
            ..:.               ..:|..|.:.:.....|::|        |... ||.|     .||
  Rat   170 PTITSTSVPQRSMAVSQPNLAMNHQHQQVVATSLSPQNH--------PAQNPPTGLMSVPNALTT 226

  Fly   686 ---HSSRLRGIRPFQPIRDFTREDFE-----------------------NGPPMSTKQIRSITIL 724
               ...:|| ::..|..|:..|...|                       |.|.|:| .:||:|..
  Rat   227 QQQQQQKLR-LQRIQMERERIRMRQEELMRQEAALCRQLPMETETMAPVNTPAMNT-DMRSVTNS 289

  Fly   725 REIPFV--VPFNKR 736
            ...||:  .|::.|
  Rat   290 SSDPFLNGGPYHSR 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033
CG3356	NP_611896.1	HECTc	788..1119	CDD:214523
Wwtr1	NP_001020040.1	WW	125..156	CDD:197736	7/30 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900