Protein Alignment CG3356 and HECW1

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: XP_016867371.1
• Gene: HECW1 / 23072
• HGNCID: 22195
• Length: 1639
• Species: Homo sapiens
• Alignment Length: 614
• Identity: 156/614 - (25%)
• Similarity: 269/614 - (43%)
• Gaps: 108/614 - (17%)

  Fly   562 FVENKLLLQVHSTINHV-------RLMPFSIAEIIQMSKTLKDISMGLVELAFPETRSNLANYRK 619
            |::.::.||.....||:       ||..:|..|..::|:     :.|...||.|
Human  1079 FIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEASEVSR-----NRGASLLARP----------- 1127

  Fly   620 VLGHTEADDKKLRHQKQIWANLLN--VVVFV---------------LNQIHTRDLRLGFCPEDHW 667
              ||:.....:.:||.:......|  :|.|:               |.:.||...::      |:
Human  1128 --GHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHTLREKI------HY 1184

  Fly   668 TVTRLDLPLDR---PTDLPLTHSSRLRGIRPFQPIRDFTREDFENGP-------PMSTKQIRSIT 722
            ..|..:..|::   ..||.:..|.....|..:.|::......:...|       |.::..::..:
Human  1185 IRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQAAFHPGYSFSPRCSPCSSPQNSPGLQRAS 1249

  Fly   723 ILREIPFVVPFNKRVSILQSLVAASKMRVQGNMQAFLQGP-SVLITVRRSHLYEDAYDKLRPDNE 786
            .....|:...|..::....     .|:..:|    |.||| .:.:.:||.||.|..::::...:.
Human  1250 ARAPSPYRRDFEAKLRNFY-----RKLEAKG----FGQGPGKIKLIIRRDHLLEGTFNQVMAYSR 1305

  Fly   787 PDL-RFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDN----KLYPNPN 846
            .:| |.|..:.||.     |.|:|..|..|||...|.:..|:|..|.|..:.::    ::.|
Human  1306 KELQRNKLYVTFVG-----EEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISP--- 1362

  Fly   847 VADLFEDYEKHYYFIGRILGKSIYENLLVELPLAEFF-------LTKLAGKYSDVDIHQLASLDP 904
            ::...|::.:.:.|.|||||.::....|::    .||       |.:|     ..|:..|..||.
Human  1363 MSAFVENHLEWFRFSGRILGLALIHQYLLD----AFFTRPFYKALLRL-----PCDLSDLEYLDE 1418

  Fly   905 ELYRNLLYLKDYSGDVSE-LNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKL 968
            |.:::|.::||  .:::: |:|.|||.....||....|||..|.:..||..|:.||::.:..:::
Human  1419 EFHQSLQWMKD--NNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRV 1481

  Fly   969 NVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISG-AEIPIDLEDLKKHCEYGGEFSPEHPS 1032
            ...:.:...|..:|...|:....:.:|..:||:::|:| ||  |||.|.:.:.||.|.:...|..
Human  1482 ERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAE--IDLNDWRNNTEYRGGYHDGHLV 1544

  Fly  1033 IVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPP-----FFIQNTGDMERLPTASTCTN 1092
            |..||..:|.|::.||.:||:|||..|..|..||..|...     |.|:..|.:..||.|.||.|
Human  1545 IRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFN 1609

  Fly  1093 LLKLPPFKTVEQMREKLLYAIQSGAGFEL 1121
            .|.|||:.:...:.||||.|::..:.|.|
Human  1610 RLDLPPYPSYSMLYEKLLTAVEETSTFGL 1638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	112/372 (30%)
		HECTc	788..1119	CDD:214523	107/349 (31%)
HECW1	XP_016867371.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810