Protein Alignment CG3356 and oxi-1

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: NP_499392.1
• Gene: oxi-1 / 176515
• WormBaseID: WBGene00003898
• Length: 1066
• Species: Caenorhabditis elegans
• Alignment Length: 1262
• Identity: 303/1262 - (24%)
• Similarity: 486/1262 - (38%)
• Gaps: 362/1262 - (28%)

  Fly    26 DTVIR---KAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDGIVED 87
            |.::|   |.|.||::....|::...|..|:.|...::.|::.....:.....:.....|  :|.
 Worm     2 DNILRTLQKNAREREEEETQRRRIELAHKLEPYLIGYLTRKKFHGKIKTFRPTFFNDFND--LEK 64

  Fly    88 ESLT------FLLRRLNFFYSIREAKDSERLIEVCQQIL-------------------------- 120
            .:.|      .|::......:.||.||.:.|..:|:.::
 Worm    65 SNKTLLPVAQMLVKVPRVIENSRENKDIQMLCNICRHLIISIDSPSKEISFVAAFLNKDTIKEAT 129

  Fly   121 -------------------RQPARLLQHS---------SPDSLWLL-RLCKLLDT-----CLLQL 151
                               .:.|.|.|..         |..|.||| |....:.|     |:..:
 Worm   130 SLITSIFSQIPQILCSINGERAAELKQWQCLIHFVIVFSSSSNWLLVRNAPQVQTVLNGLCVKMM 194

  Fly   152 SLSHTAQAIPLRMLETFTTVSSVQQYMKDEAVLFQYMERVFGFLIARNYFVRLRRLLDDKCPPLD 216
            ||.:..:.........|.:|:..:..:..|.|..|     |..|                |.||.
 Worm   195 SLFYEPKGYEQMATSLFVSVNGHKPLINVETVNAQ-----FSIL----------------CKPLK 238

  Fly   217 GETLHAPSPLAEALLQLLLRP----------LEVAK------------RASAGGQMSSMSMAVCR 259
            .|.   |...:..:|::|..|          :|:.|            ||:|....:.|.:.:..
 Worm   239 TEN---PELFSIFVLKVLTCPALLVHLNAQHVELLKTTKIFEKTLHWLRANAEEIETGMDVRLLI 300

  Fly   260 NFTRDILATPHTDPLRYFVLPCFALNVDFPFDLLMRSLYDALESAGPAESDST-------SSRRS 317
            |...:::   |           ||...|   ..|...||:...:.|.:.|..|       .::.|
 Worm   301 NLLANLV---H-----------FAYIND---KTLESKLYEWTWAVGVSLSRCTELTVKHGGTKTS 348

  Fly   318 FLFYGVETGHKTTRMDSIFSSFLLNSLMVLDRRQLATLHQSPLLVIYVRLIAEMMPNILQLPK-- 380
            ..::....||....:|......|.|.|.     ||..|..|       |::..:..||::..|
 Worm   349 LHYWHPVFGHYLLPIDKRTEGALRNVLF-----QLKMLWSS-------RVVRCLFGNIMENTKTA 401

  Fly   381 --STLRGHANAPH---------RHRDGDDDSEESEDEDEELPAARTLDYDMEQTCRTSGELSVKE 434
              |...|..|:..         |...|..||..|..:.|..|...
 Worm   402 SFSVTDGQKNSKDISAAFSKLWRKLGGSTDSASSSSKSESEPPPT-------------------- 446

  Fly   435 RECLLESIAILNETERVDFIVQQLDPHIENTHLIYALCEI---CHNLMIYNKHAVFEYKLLYTLA 496
                                            ||..:|::   ..|.|::.|.     :::..|.
 Worm   447 --------------------------------LIAIVCQVYMTALNTMVHMKG-----EIISGLC 474

  Fly   497 FTPKFIRAVWFKL----------------AAESTQLG-FSAPLTLISKGVVPKHQGVDRTIPLLA 544
            ...:.::.:|..|                ::.:.|.| .||.|..:.:...| |...      |.
 Worm   475 RDDQLLKQLWTYLREWGEKAGGTSGSIFNSSNAEQWGPVSASLQSLKRPSSP-HTAT------LR 532

  Fly   545 TFCMLFGRLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEIIQMSKTLKDISMGLVELAFPE 609
            .|......::..|.:.|..|.:              .|||..|:..:.|.:
 Worm   533 LFVDCAAAIISILDEEEIFEKE--------------TPFSNKELESICKYV-------------- 569

  Fly   610 TRSNLANYRKV----LGHTEADDKKLRHQKQIWANLLNVVVFVLNQIHTRDLRLGFCPED--HWT 668
               |:..:|.:    :..|.|:...|.|...   :||.|       ::.||.|..|...|  .|.
 Worm   570 ---NIFCFRSIWSGAVDETSANTTGLFHSMH---SLLTV-------LYERDSRRSFAANDSKFWL 621

  Fly   669 VTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENGPPMSTKQIRSITILREIPFVVPF 733
            ::.:     :|:.|.:.:..                           |..:.:.::|::..:||.
 Worm   622 ISEV-----KPSSLTIEYEK---------------------------KSGKGVLMMRKMAHLVPI 654

  Fly   734 NKRVSILQSLVAASKMRVQGNMQAFLQGPSV--LITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQ 796
            ..|:.:.:..|...|.||..:    |..|.:  .|||:|:.:.||.::.|.....|.|:...|::
 Worm   655 KDRMLLFRRQVQDDKNRVATS----LNDPQMQTWITVQRNRIIEDGFNHLSKLTIPALKSTIRVK 715

  Fly   797 FVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDNKLYPNPNVADLFEDYEKHYYFI 861
            ||:..||||||||..|||:|||...:|..|||....|..|:...|||:| .:.|.:|:...:.|:
 Worm   716 FVNEQGLDEAGIDQDGVFKEFLELTLKKVFDPQLNLFSTTSTGVLYPSP-TSSLHDDHLALFTFV 779

  Fly   862 GRILGKSIYENLLVELPLAEFFLTKLAGKYSDVDIHQLASLDPELYRNLLYLKDYSGDVSELNLD 926
            ||:|||::||.::|::.||...|..:.|.:......:|:.|||||||:|.::|.|.|::::|:|.
 Worm   780 GRMLGKAVYEGIVVDVQLAPVLLAAVLGSHRLCAFDELSQLDPELYRSLTFVKRYEGEMADLSLT 844

  Fly   927 FTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEW 991
            |:|....:|:...|:|.|.|::|.|||.|:|:|:..:|.:::..:.:..|.||..|:.::|...|
 Worm   845 FSVDEDFMGKISTVDLVPSGRTISVTNENKIDYVHRMAHHRVFRRTQEQCKAFVTGMQSILQPTW 909

  Fly   992 LYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEG-FDDMQRRQLLKFV 1055
            |.:|:..:||.||||....|||.|||::.:|.|.|...|..|...|::||. |...:|:..||||
 Worm   910 LSLFAPNDLQCLISGVNSDIDLADLKRNVQYFGGFHGNHRLIKWLWDILENKFTSEERKLFLKFV 974

  Fly  1056 TSCSRPPLLGFKDLDPPFFI--------QNTGD-----------------MERLPTASTCTNLLK 1095
            |||||||:|||..|:|||.|        |:.||                 ..||||||||.||||
 Worm   975 TSCSRPPVLGFSYLEPPFSIRCVEVSDDQDQGDTLGSVVRGFLALRKGTAATRLPTASTCFNLLK 1039

  Fly  1096 LPPFKTVEQMREKLLYAIQSGAGFELS 1122
            ||.:.....:.|||.|||.:|.|||||
 Worm  1040 LPNYNKKSLLLEKLRYAIHAGTGFELS 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	154/379 (41%)
		HECTc	788..1119	CDD:214523	145/356 (41%)
oxi-1	NP_499392.1	HECTc	684..1064	CDD:238033	154/380 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1163565at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100865
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1831
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750