DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3356 and Magi1

DIOPT Version :9

Sequence 1:	NP_611896.1	Gene:	CG3356 / 37876	FlyBaseID:	FBgn0034989	Length:	1122	Species:	Drosophila melanogaster
Sequence 2:	XP_006505643.1	Gene:	Magi1 / 14924	MGIID:	1203522	Length:	1484	Species:	Mus musculus

Alignment Length:	132	Identity:	35/132 - (26%)
Similarity:	52/132 - (39%)	Gaps:	31/132 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   854 YEKHYYFIGR-----ILGKSIYENLLVELPLAEFFLT-KLAGKYSDVD----IHQLASLDPELYR 908
            ||.:||...:     :.||.|..:.|..|.......| |....|:|:.    :|      ||
Mouse   182 YEGNYYGTPKPPSQPVSGKVITTDALHSLQSGSKQSTPKRTKSYNDMQNAGIVH------PE--- 237

  Fly   909 NLLYLKDYSGDVSELNLDFTVASSSLGQTQIVE--LKPQGQSI---PVTNSNR--IEYLQLIADY 966
                 .:...||.|:|..||..|....:..:.|  |.|...||   |:|:.::  .:||.|.|:.
Mouse   238 -----NEEEEDVPEMNSSFTADSGDQDEHTLQEATLPPVNSSILAAPITDPSQKFPQYLPLSAED 297

  Fly   967 KL 968
            .|
Mouse   298 NL 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	35/132 (27%)
CG3356	NP_611896.1	HECTc	788..1119	CDD:214523	35/132 (27%)
Magi1	XP_006505643.1	PDZ_signaling	15..100	CDD:238492
		GuKc	122..293	CDD:214504	32/124 (26%)
		WW	302..331	CDD:366073
		WW	362..393	CDD:197736
		PDZ	462..548	CDD:214570
		PDZ	633..716	CDD:214570
		MAGI_u5	715..798	CDD:374709
		PDZ_signaling	840..915	CDD:238492
		PDZ_signaling	989..1084	CDD:238492
		PDZ	1145..1227	CDD:214570
		PRK12678	1203..>1452	CDD:237171
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900