Protein Alignment CG3356 and Herc4

DIOPT Version :10

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: XP_061505038.1
• Gene: Herc4 / 1270105
• VectorBaseID: AGAMI1_002839
• Length: 1060
• Species: Anopheles gambiae
• Alignment Length: 751
• Identity: 186/751 - (24%)
• Similarity: 311/751 - (41%)
• Gaps: 146/751 - (19%)

  Fly   442 IAILNETERVDFIVQQLDPHIENTHLIYALCEICHNLMIYNKHAVFEYKLLYTLAFTPKFIRAVW 506
            :::|...|..||.|     :.::|.::....|:...|.........|..::.:       :..::
Mosquito   384 VSLLGGDESADFRV-----YDDSTQILSLSLEMGKELAKIEPEQTVELDVISS-------VETIF 436

  Fly   507 FKLAA--ESTQLGFSAPLTLISKGVVPKHQGVD----------------RTIPLLATFCM---LF 550
            ..||.  .|..|...|.|...|     ||.|||                .:|..|....:   |.
Mosquito   437 KSLACLNGSLLLPNDAHLCCTS-----KHPGVDMGAAEETFDQIRKIERESIRQLIRDSIESDLL 496

  Fly   551 GRLLPTLHDVEFVENKLLLQV-HSTIN--HVRLM--PFSIAEIIQMSKTLKDISMG--------- 601
            |.|..:..|||.:...|||.: |..||  |.:.:  |||.| ::|::|...:|.:|
Mosquito   497 GALTASPADVETLRIYLLLPLYHEFINPKHYQKLHAPFSKA-VLQLAKNAYEIVVGWWANQSREY 560

  Fly   602 --------------LVELAFPETRSNLANYRKVLGHTEADDKKLRHQKQIWA--NLLNVVVFVLN 650
                          ::...||...|       ..|..:...::||:...:.|  ::|.|:.::.:
Mosquito   561 FERMVENCKSVVLYIINFKFPRVES-------PAGAEKPHQQELRYDPHLAAMLDMLAVLYWINH 618

  Fly   651 QIHTRDLRLGFCPEDHWTVTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENGPPMST 715
            |..|:.|     |.:.:.:..:|..:|                         .|:|:...    |
Mosquito   619 QKRTQKL-----PYEQFHINEIDDLID-------------------------IRQDYFRW----T 649

  Fly   716 KQIRSITI-LREIPFVVPFNKRVSILQS-----LVAASKMRVQGNMQAFLQGPS--------VLI 766
            ...:.:|. |...|||...:.::.:||:     :..|.:.....:..:.|..|:        :::
Mosquito   650 TDAKGVTFSLCNYPFVFNASAKMLLLQTDQAMQMYQAMQSAATASWLSMLYSPAANSAACQYIVL 714

  Fly   767 TVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRG 831
            .|.|.::.:|...:|......||:...:|:|..     |...|.|||.:||...|::...||..|
Mosquito   715 NVTRENIVQDTIRELSHYAASDLKKPIKIKFCG-----EEAEDAGGVRKEFFMLLLRDILDPKYG 774

  Fly   832 FFMVTTDNKLYPNPNVADLFEDY----EKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGKYS 892
            .|      |.:...|.....|||    :..:..||.:.|.:||...::.||.......||.|:
Mosquito   775 MF------KSFEESNAIWFTEDYFDSDDSMFALIGILCGLAIYNFTIIALPFPLALYKKLLGE-- 831

  Fly   893 DVDIHQLASLDPELYRNLLYLKDY-SGDVSEL-NLDFTVASSSLGQTQIVELKPQGQSIPVTNSN 955
            :||:..|..|.|.:.|::..:.|| .||:.|: :|.||......|:.|.:.|||.|::|.:|..|
Mosquito   832 EVDMKDLQDLAPTVARSMQSILDYEGGDLEEVFDLCFTTTRDYFGEIQTIPLKPNGENIRLTQGN 896

  Fly   956 RIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHC 1020
            :.|::.|..||..|..:.:....|..|...|.....:.:|...||..::.|.| ..|...|:::.
Mosquito   897 KQEFVNLYIDYVFNKAVEKSFRQFHAGFMRVCGGRVMKLFKAHELMSVVVGNE-EYDWNVLEENA 960

  Fly  1021 EYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPPFFIQNTGDMERLP 1085
            ||...::....:|..||||.......::::.|.|:|.|.|.|::|.|.:  ..|||.|.|.:.||
Mosquito   961 EYKNGYTCGDQTIRWFWEVFHELPLEEKKKFLLFLTGCDRIPIMGMKAI--KIFIQPTPDDKFLP 1023

  Fly  1086 TASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGFEL 1121
            .|.||.|||.||.::|.|:::.|||.|||...||.|
Mosquito  1024 VAHTCFNLLDLPQYQTKEKLKYKLLQAIQQTQGFSL 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	112/359 (31%)
Herc4	XP_061505038.1	None