Protein Alignment CG3356 and Ubr5

DIOPT Version :9

• Sequence 1: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Sequence 2: XP_038936091.1
• Gene: Ubr5 / 117060
• RGDID: 621236
• Length: 2798
• Species: Rattus norvegicus
• Alignment Length: 1152
• Identity: 245/1152 - (21%)
• Similarity: 408/1152 - (35%)
• Gaps: 368/1152 - (31%)

  Fly   160 IPLRMLETFTTVSSVQQYMKDEAV-LFQYMERVFGFLIAR-NYFVRLRRLLDDKCPPLDGETLHA 222
            ||..:..|:....::|.|::::.: .:.:|..:.....|: .|...|....|   |......|||
  Rat  1813 IPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGD---PGHPNHPLHA 1874

  Fly   223 PSPLAE-----ALLQLLLRPLEVAKRA----------SAGGQMSSMSMAVCRNFTRDILATPHTD 272
            ....|.     |..:..||.||..:||          ||.|...:.::::.|:...:     |:|
  Rat  1875 SQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNYALSLMRSHNDE-----HSD 1934

  Fly   273 PLRYFVLP----CFALNVDFPFDLLMRSLYDALESAGPAESDSTSSRRSFLFYGVETGHKTTRMD 333
                 |||    |...:|.:.|..|:                          |.::..::.|.:|
  Rat  1935 -----VLPVLDVCSLKHVAYVFQALI--------------------------YWIKAMNQQTTLD 1968

  Fly   334 SIFSSFLLNSLMVLDRRQLATLHQSPLLVIYVRLIAEMMPNILQLPKSTLRGHANAPHRHRDGDD 398
            :          ..|:|::...|                    |:|      |..|....|.:.||
  Rat  1969 T----------PQLERKRTREL--------------------LEL------GIDNEDSEHENDDD 1997

  Fly   399 DSEE---SEDEDEELPAA--------RTLDYDMEQTCRTSGELSVKERECLLESIAILNETERVD 452
            .|:.   ::.:||.|||.        |..|......|.......|.    |.|:|.:.::.
  Rat  1998 TSQSATLNDKDDESLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVP----LAEAIPLADQP---- 2054

  Fly   453 FIVQQLDPHIENTHL-------IYA--------LCEICHNLMIYNKHAVFEYKLLYTLAFTPKFI 502
               ..|.|:.....|       :|:        |.|:   .|..|...|...|:.|  |...|.:
  Rat  2055 ---HLLQPNARKEDLFGRPSQGLYSSSAGSGKCLVEV---TMDRNCLEVLPTKMSY--AANLKNV 2111

  Fly   503 RAVWFK----------LA--AESTQLGFSA-------PLTLISKGVVPKHQGVDRTIPLLATF-- 546
            ..:..:          ||  |:|::.|.||       ..:|:::..:.:.:|     |.|.:|
  Rat  2112 MNMQNRQKKAGEDQSMLAEEADSSKPGPSAHDVAAQLKSSLLAEIGLTESEG-----PPLTSFRP 2171

  Fly   547 -CMLFGRLLPTLHDVEFVENKLLLQVHSTI--NHVRLMPFSIAEIIQMSKTLKDISMGLVELAFP 608
             |...|.::.  ||:.....:|.|::...:  ..|...|.||                |.||...
  Rat  2172 QCSFMGMVIS--HDMLLGRWRLSLELFGRVFMEDVGAEPGSI----------------LTELGGF 2218

  Fly   609 ETRSNLANYRKVLGHTEADDKKLRHQKQIWANLLNVVV----FVLNQIHTRDLRLGF---CPEDH 666
            |.:.  :.:|:.:       :|||:|:   :..|::.|    .:|.|...|.|...|   |....
  Rat  2219 EVKE--SKFRREM-------EKLRNQQ---SRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTP 2271

  Fly   667 WTVTRLDLPL-DRPTD---------------------LPL----------THSSRLRGIRPFQPI 699
            ..|.|:.:.. |.|.:                     ||.          ||:|.::.:|. :..
  Rat  2272 MAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLDCIQNANKGTHTSLMQRLRN-RGE 2335

  Fly   700 RDFTRE---------------------DFENGPPMSTKQIR--SITILREIPFVVPFNKRVSILQ 741
            ||..||                     ||.....:.|:..|  |.....:.|..:|.::     |
  Rat  2336 RDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPDPLPAHR-----Q 2395

  Fly   742 SLVAASKMRVQGNMQAFLQ---------GPSVLITVRRSHLYEDAYDKLRP-------------- 783
            :|......|||....||..         .|:.|:.:..|.      |.||.
  Rat  2396 ALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASE------DSLRARVEEAMELIVAHGR 2454

  Fly   784 DNEPD-------LRFKFRIQ----------FVSSLGLDEA--GIDGGGVFREFLSELIKTAFDP- 828
            :|..|       |....::|          .|..:.||:.  |.|...:|           :.|
  Rat  2455 ENGADSILDLGLLDSSEKVQENRKRHGSSRSVVDMDLDDTDDGDDNAPLF-----------YQPG 2508

  Fly   829 NRGFFMVTTDNKLYPNPNVADLFEDYEKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGKYSD 893
            .|||:...      |..|.......:..    ||||||..:.:|.|..:.|....:..|.|:  .
  Rat  2509 KRGFYTPR------PGKNTEARLNCFRN----IGRILGLCLLQNELCPITLNRHVIKVLLGR--K 2561

  Fly   894 VDIHQLASLDPELYRNL--LYLKDYSGDV----SELNLDFTV---ASSSLGQTQIVELKPQGQSI 949
            |:.|..|..||.:|.:|  |.|...|.|.    |.::|.|.|   .....||   |||.|.|.:|
  Rat  2562 VNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAVDLCKEEGGGQ---VELIPNGVNI 2623

  Fly   950 PVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLE 1014
            |||..|..||::..|::::.|...:..:|.||||.:|||...|...:.::.::|::|.. .::::
  Rat  2624 PVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCG-EVNVQ 2687

  Fly  1015 DLKKHCEYGGEFSPEHPSIVT----FWEVLEGFDDMQRRQLLKFVTSCSRPPLL--GFKDLD--- 1070
            .|.....:..|.......::.    ||.::|.....:|:.|:.|.||....|..  ||:.:.
  Rat  2688 MLISFTSFNDESGENAEKLLQFKRWFWSIVERMSMTERQDLVYFWTSSPSLPASEEGFQPMPSIT 2752

  Fly  1071 --PPFFIQNTGDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQS 1115
              ||       |.:.||||:||.:.|.:|.:.:.:.:::|||.||::
  Rat  2753 IRPP-------DDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKT 2792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	102/404 (25%)
		HECTc	788..1119	CDD:214523	97/368 (26%)
Ubr5	XP_038936091.1	CUE_UBR5	184..230	CDD:270606
		ZnF_UBR1	1177..1244	CDD:197698
		PolyA	2389..2452	CDD:197769	14/73 (19%)
		HECTc	2500..2795	CDD:214523	89/327 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000