DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cN-IIIB and Nt5c3a

DIOPT Version :9

Sequence 1:	NP_611895.1	Gene:	cN-IIIB / 37875	FlyBaseID:	FBgn0034988	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_006236614.1	Gene:	Nt5c3a / 312373	RGDID:	1312013	Length:	331	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	113/302 - (37%)
Similarity:	188/302 - (62%)	Gaps:	9/302 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FDEKREPTGGRLR-LQDIPALTQDHCRMRDPAEVERIINEFVIGGPERMQIVSDFDYTITKQRTE 66
            |..||: ||.:.: ::.:|...:...|:::|..||.||...:.||..::||::|||.|::: .:.
  Rat    31 FTLKRK-TGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKGGAAKLQIITDFDMTLSR-FSY 93

  Fly    67 DGGAVPSSFGIFNACQSLPENFKAETDKLYHKYRPIEIDPHMPIAEKVQYMIEWWTKSGEL--TS 129
            :|...|:...|.:.|:.:.:..:.:..:|..:|..||:||.:.:.||..||:||:|||..|  ..
  Rat    94 NGKRCPTCHNIIDNCKLVTDECRRKLLQLKEQYYAIEVDPVLTVEEKFPYMVEWYTKSHGLLIEQ 158

  Fly   130 GFPFDQSEIDQIASKYTHALRDRTHEFFADLQRLGIPTLVFSAGLGNSVVSVLRQANVLHPNVKV 194
            |.|  ::::.:|.:.....|::....||..||:.|||..:||||:|:.:..|:|||.|.|.||||
  Rat   159 GIP--KAKLKEIVADSDVMLKEGYENFFGKLQQHGIPVFIFSAGIGDVLEEVIRQAGVYHSNVKV 221

  Fly   195 VSNFLQF-RDGLLDGFQQPMIHTFNKNETVLNETSEYYDLVHTRDHIIVMGDSIGDADMASGVPA 258
            ||||:.| .:|:|.||:..:||.|||::..|..| :|:..:....:||::|||.||..||.||..
  Rat   222 VSNFMDFDENGVLKGFKGELIHVFNKHDGALKNT-DYFSQLKDNSNIILLGDSQGDLRMADGVAN 285

  Fly   259 SSHIMKIGFLFDHVEANMKKYMDTFDIVLVDDQTMDVPRTLL 300
            ..||:|||:|.|.|:..::||||::|||||.:::::|..::|
  Rat   286 VEHILKIGYLNDRVDELLEKYMDSYDIVLVKEESLEVVNSIL 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cN-IIIB	NP_611895.1	HAD-SF-IE	22..303	CDD:273683	107/282 (38%)
Nt5c3a	XP_006236614.1	HAD_like	50..329	CDD:304363	107/282 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343846
Domainoid	1	1.000	200	1.000	Domainoid score	I2946
eggNOG	1	0.900	-	-		E1_KOG3128
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	229	1.000	Inparanoid score	I3375
OMA	1	1.010	-	-		QHG57847
OrthoDB	1	1.010	-	-		D1171042at2759
OrthoFinder	1	1.000	-	-		FOG0003221
OrthoInspector	1	1.000	-	-		otm45029
orthoMCL	1	0.900	-	-		OOG6_103467
Panther	1	1.100	-	-	O	PTHR13045
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2179
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810