DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ocm and Tbx19

DIOPT Version :9

Sequence 1:	NP_001188998.1	Gene:	ocm / 37874	FlyBaseID:	FBgn0266083	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_114394.1	Gene:	Tbx19 / 83993	MGIID:	1891158	Length:	446	Species:	Mus musculus

Alignment Length:	262	Identity:	64/262 - (24%)
Similarity:	89/262 - (33%)	Gaps:	79/262 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1308 NEEILCI-IKWTNFLAAF----ESGFV-----FIWDVQMKTHNFLAATTTNLMPSVCGAIAVVNT 1362
            ||||..: ||:..|..||    |...:     .|.:.|..|::.|.....:....||.| |..|.
Mouse   197 NEEITALKIKYNPFAKAFLDAKERNHLKDVPEAISESQHVTYSHLGGWILSNPDGVCTA-ANSNY 260

  Fly  1363 KFA-----PDP----------------QALPLMARMLMN-----SMRNEKTNRLAVVMQGRQSFW 1401
            ::|     |.|                ||....|.|..|     ::....:|.|. |..|..| |
Mouse   261 QYATPLPLPAPHTHHGCEHYAGLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQ-VFSGPDS-W 323

  Fly  1402 LVKGFLRHM------QGNACTKPTPMTHPLLTKKINVLCSLLVKQRVRENEKKTLGDGSGAPYEV 1460
            .......|.      ..|....|.|..:|.|.                     |:.:|.|.|  |
Mouse   324 TSLSSTPHASILSVPHSNGPINPGPSPYPCLW---------------------TISNGGGGP--V 365

  Fly  1461 LAG-DVSPQTS--LLMKNRSRDLKRKSQADERLLPSGPSMTKSSKPSAGGYPIAASVATSTTSAF 1522
            .:| :|...||  :|:.|.:      ..:...|||:  ..|.|:.....|.|...|:|.||.:|.
Mouse   366 ASGSEVHASTSGTILLGNPA------VTSPSSLLPT--QATTSAGVEVLGEPSLTSIAVSTWTAV 422

  Fly  1523 AS 1524
            ||
Mouse   423 AS 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
Tbx19	NP_114394.1	TBOX	39..221	CDD:214656	10/23 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830