Protein Alignment ocm and TBX5

DIOPT Version :10

• Sequence 1: NP_611894.1
• Gene: ocm / 37874
• FlyBaseID: FBgn0266083
• Length: 2175
• Species: Drosophila melanogaster
• Sequence 2: XP_016875401.1
• Gene: TBX5 / 6910
• HGNCID: 11604
• Length: 534
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 60/331 - (18%)
• Similarity: 107/331 - (32%)
• Gaps: 81/331 - (24%)

  Fly    42 SVSPEMLEKMMATGMNIARLNFSHGSHEYHANTIKNIRE---------AVDNYSKKLGKPFPLAI 97
            ||.....|..||..:.:.....|...|:...|..|...:         .||.|||..|:...|.:
Human    16 SVGISRKELAMAEALQMEYDALSRLRHDKEENRAKQNADPSLISWDEPGVDFYSKPAGRRTDLKL 80

  Fly    98 --ALDTKGPEIR-TGLIEGSGTGEVELKKGEKIQLTTDKEHLEKGTKDKIYVDYVNIVKVVKPGD 159
              .|....|.:. ..|....|.......:|.:    ...:...||:..               ||
Human    81 LRGLSGSDPTLNYNSLSPQEGPPNHSTSQGPQ----PGSDPWPKGSLS---------------GD 126

  Fly   160 HVFVDDGLISLVVESISGDTLTCTVENGGMLGSRKGVNLPGVPV-----DLPAVSEKDKSDLAFG 219
            ::::.||         |...::.:...|.:.||.|.::.|.:|.     |.|.:..:..|..:..
Human   127 YLYIFDG---------SDGGVSSSPGPGDIEGSCKKLSPPPLPPRASIWDTPPLPPRKGSPSSSK 182

  Fly   220 VEQGVDVIFASFIRNAAA------LKEIRTILGEKGKHIKIISKIE-----------NQQGMQNL 267
            :.|..|:...|.:.....      :.|...:||..|:. :::..::           |.:...:.
Human   183 ISQPSDINTFSLVEQLPGKLLEHRILEEEEVLGGGGQG-RLLGSVDYDGINDAITRLNLKSTYDA 246

  Fly   268 DKIIEATDGIMVARGDLGIEIPAEKVFLAQKSMIARCNRAGKPVICATQMLESMIKKPRPTRAEI 332
            :.:.:||.|....||.|...                .:.:||||..:..|...:  .||...:..
Human   247 EMLRDATRGWKEGRGPLDFS----------------KDTSGKPVARSKTMPPQV--PPRTYASRY 293

  Fly   333 SDVANA 338
            .:..||
Human   294 GNRKNA 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_611894.1	MGA_dom	771..821	CDD:464998
		PRK12323	<1933..>2053	CDD:481241
TBX5	XP_016875401.1	T-box_TBX4_5-like	70..254	CDD:410315	33/212 (16%)