DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ocm and tbx20

DIOPT Version :9

Sequence 1:	NP_001188998.1	Gene:	ocm / 37874	FlyBaseID:	FBgn0266083	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001030292.1	Gene:	tbx20 / 619590	XenbaseID:	XB-GENE-487334	Length:	440	Species:	Xenopus tropicalis

Alignment Length:	323	Identity:	70/323 - (21%)
Similarity:	117/323 - (36%)	Gaps:	85/323 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1862 TSSSSSHLPASKSAYPKINESLQELFSSGVPPGGITITKVDSQEKTL-PNETVQVVKNKK----- 1920
            |.|....|.:..:|:     |:..|.|||.|      ...::||.|: |.|  |.|:...
Frog     4 TPSPKPQLSSRANAF-----SIAALMSSGTP------KDKETQESTIKPLE--QFVEKSSCSQPL 55

  Fly  1921 -SIAITGIHKQVTKAASSTATVTAARAPVVKPQSTSVSKVAPPIRPGATTQPKTLVRLYPK---- 1980
             .|:|...|.:.|.:.||..|........|.| |..::|::      .:.:.|   .|:.|
Frog    56 GDISIVDSHGEFTNSPSSLCTEPLIPTTPVIP-SEEMAKIS------CSLETK---ELWDKFHDL 110

  Fly  1981 ----PALAAGRKSLPANAKTPVATPRQS-QPVACDKPPLVSGSTLPALVEPSARKSLPSKPLAAG 2040
                ....:||:..|        |.|.| ..|..|...:|....:|          :.:|.....
Frog   111 GTEMIITKSGRRMFP--------TIRVSFSGVDADAKYIVLMDIVP----------VDNKRYRYA 157

  Fly  2041 EHLRPRQSLPAKVTANPPAAAR----PDAASTSAQ---NLTNVSKAQLAKEEI-CYGIMVAKDLP 2097
            .|   |.|......|:||..||    ||:..|..|   .:.:..|.:|...|: .:|.::...:.
Frog   158 YH---RSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMH 219

  Fly  2098 RFRAKVEGSDFMIKIPEHGVFRFKTFGLAASFLSRHVAKDPKLKQFLPAEWKFHPLEQFNKQV 2160
            :::.:|.    :||..:|          .||.|:   .|..:.:.|:..|..|..:..:..|:
Frog   220 KYQPRVH----IIKKKDH----------TASLLN---LKSEEFRTFIFQETVFTAVTAYQNQL 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
tbx20	NP_001030292.1	T-box	96..282	CDD:366363	42/211 (20%)
tbx20	NP_001030292.1	T-box	98..282		42/209 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100