DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ocm and Tbx20

DIOPT Version :9

Sequence 1:	NP_001188998.1	Gene:	ocm / 37874	FlyBaseID:	FBgn0266083	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_919239.1	Gene:	Tbx20 / 57246	MGIID:	1888496	Length:	445	Species:	Mus musculus

Alignment Length:	333	Identity:	64/333 - (19%)
Similarity:	119/333 - (35%)	Gaps:	100/333 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1862 TSSSSSHLPASKSAYPKINESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVVK---NKKSIA 1923
            |:|....|.:..:|:     |:..|.|||.|           :||.....|::.::   .|.|.|
Mouse     4 TASPKPQLSSRANAF-----SIAALMSSGGP-----------KEKEAAENTIKPLEQFVEKSSCA 52

  Fly  1924 -----ITGI--HKQVTKAASSTATVTAARAPVVKP----QSTSVSKVAPPIRPGATTQPKTLVRL 1977
                 :|.:  |.:......|.::.:....|::..    .|..::|:|      .:.:.|.|...
Mouse    53 QPLGELTSLDAHAEFGGGGGSPSSSSLCTEPLIPTTPIIPSEEMAKIA------CSLETKELWDK 111

  Fly  1978 YPKPA-----LAAGRKSLPANAKTPVATPRQSQPVACDKPPLVSGSTLPALVEPSAR-------K 2030
            :.:..     ..:||:..|        |.|.|          .||      |:|.::       .
Mouse   112 FHELGTEMIITKSGRRMFP--------TIRVS----------FSG------VDPESKYIVLMDIV 152

  Fly  2031 SLPSKPLAAGEHLRPRQSLPAKVTANPPAAAR----PDAASTSAQ---NLTNVSKAQLAKEEI-C 2087
            .:.:|......|   |.|......|:||..||    ||:..|..|   .:.:..|.:|...|: .
Mouse   153 PVDNKRYRYAYH---RSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQ 214

  Fly  2088 YGIMVAKDLPRFRAKVEGSDFMIKIPEHGVFRFKTFGLAASFLSRHVAKDPKLKQFLPAEWKFHP 2152
            :|.::...:.:::.:|.    :||..:|          .||.|:   .|..:.:.|:..|..|..
Mouse   215 HGHIILNSMHKYQPRVH----IIKKKDH----------TASLLN---LKSEEFRTFIFPETVFTA 262

  Fly  2153 LEQFNKQV 2160
            :..:..|:
Mouse   263 VTAYQNQL 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
Tbx20	NP_919239.1	TBOX	98..290	CDD:238106	43/223 (19%)
Tbx20	NP_919239.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..337
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831500
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930