Protein Alignment ocm and TBX20

DIOPT Version :9

• Sequence 1: NP_001188998.1
• Gene: ocm / 37874
• FlyBaseID: FBgn0266083
• Length: 2175
• Species: Drosophila melanogaster
• Sequence 2: NP_001071121.1
• Gene: TBX20 / 57057
• HGNCID: 11598
• Length: 447
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 111/593 - (18%)
• Similarity: 180/593 - (30%)
• Gaps: 205/593 - (34%)

  Fly  1498 TKSSKPSAGGYPIAASVATSTTSAFASSSGKSTPVCTAKT---------NSASTKNKSSATGIRS 1553
            |.|.||.......|.|:|     |..||.|......|..|         .|:..:.....|.:.:
Human     4 TASPKPQLSSRANAFSIA-----ALMSSGGSKEKEATENTIKPLEQFVEKSSCAQPLGELTSLDA 63

  Fly  1554 NIEFRKVNHNDVDELQIPELHQTDHRWVVLDIFDDFSHIFVPSFSDMISLTRIHSVMQVAEERQK 1618
            :.||...:.:.                              ||.|.:.:...|.:...:..|...
Human    64 HGEFGGGSGSS------------------------------PSSSSLCTEPLIPTTPIIPSEEMA 98

  Fly  1619 VVKLQFFPNAPYDAF--------VTPSSKKKIYFGPLSLDMPPPVLVLLQSVD---RKMMLREVY 1672
            .:.........:|.|        :|.|.::          |.|.:.|....||   :.::|.::
Human    99 KIACSLETKELWDKFHELGTEMIITKSGRR----------MFPTIRVSFSGVDPEAKYIVLMDI- 152

  Fly  1673 QREHSIPVQRHRRSMAF----WVLQINGQVHFEIDTESTAKLAAQQKNAIGTPPGLNVLKIPSQL 1733
                 :||...|...|:    |:      |..:.|....|:|.....:..   .|..:||   |:
Human   153 -----VPVDNKRYRYAYHRSSWL------VAGKADPPLPARLYVHPDSPF---TGEQLLK---QM 200

  Fly  1734 SVEIEKNQDEVPPVVVIDSDEEDDDGE-----------RQLVIDEQDDEQAETDVKQEVERTGFT 1787
             |..||        |.:.::|.|..|.           |..:|.::|...:..::|.|..||...
Human   201 -VSFEK--------VKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIF 256

  Fly  1788 IQTL-PSSGALQITISDSAETSSHPAKDVNTCHFSGGFMPFIANVPAKFGETAPTTQFLTPQVQV 1851
            .:|: .:..|.|..:....:..|:|        |:.||.           :::..|......|
Human   257 PETVFTAVTAYQNQLITKLKIDSNP--------FAKGFR-----------DSSRLTDIERESV-- 300

  Fly  1852 TTSQSGPETLTSSSSSHLPASKSAYPKINESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVV 1916
                                         |||.:..|....|    |.....:|..|.:|: |..
Human   301 -----------------------------ESLIQKHSYARSP----IRTYGGEEDVLGDES-QTT 331

  Fly  1917 KNKKSIAITGIHKQVTKAASSTATVTAARAPVVKPQS-----TSVSKVAPPIRPGATTQPKTLVR 1976
            .|:.|...|..:..::...||:::....:    .|||     ||.:.:|.||
Human   332 PNRGSAFTTSDNLSLSSWVSSSSSFPGFQ----HPQSLTALGTSTASIATPI------------- 379

  Fly  1977 LYPKPALAAGRKSLPANAK-----TPVATPRQSQPVACDKPPLVSGSTLPALVEPSARKSLPSKP 2036
              |.|.    :.|||..::     ||.|.....|.         ||.|.|:...|.........|
Human   380 --PHPI----QGSLPPYSRLGMPLTPSAIASSMQG---------SGPTFPSFHMPRYHHYFQQGP 429

  Fly  2037 LAAGEHLR 2044
            .||.:.||
Human   430 YAAIQGLR 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
TBX20	NP_001071121.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..81		5/48 (10%)
		T-box	102..288	CDD:307177	45/241 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..340		6/24 (25%)
		DUF853	<357..>409	CDD:331106	17/83 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930