DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ocm and tbr1a

DIOPT Version :9

Sequence 1:	NP_001188998.1	Gene:	ocm / 37874	FlyBaseID:	FBgn0266083	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_693121.1	Gene:	tbr1a / 564699	ZFINID:	ZDB-GENE-060810-93	Length:	585	Species:	Danio rerio

Alignment Length:	375	Identity:	73/375 - (19%)
Similarity:	115/375 - (30%)	Gaps:	118/375 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1735 VEIEKNQDEVPPVVVIDSDEEDDDGERQLVIDEQDDEQAETDVKQEVERTGFTIQTLPSSGALQI 1799
            :||.||:||         |..|.||.:.....|                |.|...|     |.|.
Zfish   279 IEISKNEDE---------DTSDPDGVQTFTFPE----------------TQFISVT-----AYQN 313

  Fly  1800 TISDSAETSSHPAKDVNTCHFSGGFMPFIANVPAKFGETAPTTQFLTPQVQVTTSQSGPETLTSS 1864
            |.....:...:|        |:.||..   |...|:                  |....:.||.|
Zfish   314 TDITQLKIDHNP--------FAKGFRD---NYDTKY------------------SMDNTDRLTPS 349

  Fly  1865 SSSH---LPASKSAYPK-------INESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVVKNK 1919
            .|.|   ||:|:.|.|.       ::...:..|::|.|..|:..|           .::......
Zfish   350 DSPHSQLLPSSRYAMPSALFQEQFVDSYTKSCFTTGTPERGLEFT-----------NSIMTSNQT 403

  Fly  1920 KSIAITGIHKQVTKAASSTATVTAARAPVVKPQSTSVSKVAPPIRPGATTQPKTLVRLYPKPALA 1984
            :..::|...:....:.|..:.........:...:|:..|..|....|.::..   :..|...|..
Zfish   404 QESSVTSGQRWFVSSPSVPSYEADVDTAALLSYTTAGVKNLPFTSTGGSSNS---LDYYTSTAGW 465

  Fly  1985 AGRKSLPANAKT---------PVATPRQSQP-VACDKPPLVSGSTLPALVE-------------- 2025
            ..|.||...:||         .....|..|| ...|...|:..|:|....|
Zfish   466 DSRGSLENGSKTISNLSGWVLDATLERSMQPNYLPDDRELMERSSLGVSAELRGKDVVDSTWTDT 530

  Fly  2026 PSARKSLPSKPLAAGEHLRPRQSLPAKVTANPPAAARPDAASTSAQNLTN 2075
            .|:.||:.|..|...|. .|:..|          :.|||:...:|:::.|
Zfish   531 QSSIKSVDSSDLRILEE-APKDDL----------SIRPDSEDQAAEDVQN 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
tbr1a	XP_693121.1	TBOX	142..335	CDD:238106	22/96 (23%)
tbr1a	XP_693121.1	T-box_assoc	355..550	CDD:292794	37/209 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574535
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830