DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ocm and Tbx20

DIOPT Version :9

Sequence 1:	NP_001188998.1	Gene:	ocm / 37874	FlyBaseID:	FBgn0266083	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_006242782.1	Gene:	Tbx20 / 315497	RGDID:	1309396	Length:	446	Species:	Rattus norvegicus

Alignment Length:	443	Identity:	91/443 - (20%)
Similarity:	147/443 - (33%)	Gaps:	107/443 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1481 KRKSQADERLLPSGPSMTKSSKPSAGGYPIAASVATSTTSAFASSSGKSTPVCTAKTNSASTKNK 1545
            |.|..|:..:.|....:.|||    ...|:....:....:.|....|.|     ..::|..|:..
  Rat    30 KEKEAAENTIKPLEQFVEKSS----CAQPLGELTSLDAHAEFGGGGGSS-----PSSSSLCTEPL 85

  Fly  1546 SSATGIRSNIEFRKVNHNDVDELQIPELHQTDHRWVVLDIFDDF--SHIFVPSFSDMISLTRIHS 1608
            ...|.|..:.|..|:    ...|:..||      |   |.|.:.  ..|...|...|....|: |
  Rat    86 IPTTPIIPSEEMAKI----ACSLETKEL------W---DKFHELGTEMIITKSGRRMFPTIRV-S 136

  Fly  1609 VMQVAEERQKVVKLQFFP--NAPYD-AF----------VTPSSKKKIYFGPLSLDMPPPVLVLLQ 1660
            ...|..|.:.:|.:...|  |..|. |:          ..|....::|..|.|......:|..:.
  Rat   137 FSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMV 201

  Fly  1661 SVDR-KMMLREVYQREHSIPVQRHRRSMAFWVLQINGQVHFEIDTESTAKLAAQQKNAIGTPPGL 1724
            |.:: |:...|:.|..|.|....|:         ...:||.....:.||.|...:.....|
  Rat   202 SFEKVKLTNNELDQHGHIILNSMHK---------YQPRVHIIKKKDHTASLLNLKSEEFRT---- 253

  Fly  1725 NVLKIPSQLSVEIEKNQDEVPPVVVIDSD---EEDDDGERQLVIDEQDDEQ-------AETDVKQ 1779
              ...|..:...:...|:::...:.|||:   :...|..|...|:.:..|.       |.:.::.
  Rat   254 --FIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRT 316

  Fly  1780 --EVERTGFTIQTLPSSGALQITISDSAETSS------------HP----AKDVNTCHFS----- 1821
              |.:..|...||.|:.|: ..|.||:...||            ||    |...:|...:
  Rat   317 YGEEDVLGEESQTTPNRGS-AFTTSDNLSLSSWVSSSSSFPGFQHPQPLTALGTSTASIATPIPH 380

  Fly  1822 ---GGFMPFIANVPAKFGETAPTTQFLTPQVQVTTSQ-SGPETLTSSSSSHLP 1870
               |...|:     ::.|..      |||....::.| |||    :..|.|:|
  Rat   381 PIQGSLPPY-----SRLGMP------LTPSAIASSMQGSGP----TFPSFHMP 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ocm	NP_001188998.1	DUF4801	771..821	CDD:292677
Tbx20	XP_006242782.1	TBOX	99..291	CDD:238106	43/220 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335237
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930